A portrait in history. Thomas Hodgkin.
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Jean-Martin Charcot was one of the most celebrated French physicians of the 19th century. A masterful teacher and a captivating lecturer, Charcot created the foundations of neurology as an independent discipline, and transformed the Salpêtrière hospital, in Paris, into one of the world's greatest teaching centers for clinical neurologic research. His name is attached to the distinct pathologic entity, Charcot's joint disease, that he so meticulously described. This article reviews the highlights of Charcot's career and his clinicoanatomic studies of patients with tabetic arthropathies.
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Adamantiades-Behçet disease is a multifocal entity which was first described by Hippocrates 500 years BC. The disease is characterised by relapsing oral aphthae, genital ulcers and iritis, while 24-40% of cases present with arterial or venous thromboses, arterial aneurysms or varices. In rare cases, due to invasion of different systems, the clinical picture varies, making timely diagnosis difficult. The disease is common all over the world but is more frequent in Japan, Korea, China and the Middle East. The first description in contemporary times was made by the Greek ophthalmologist Benedict Adamantiades in 1931, and the disease was described for the second time, independently, by the Turkish dermatologist Hulusi Behçet in 1937.
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