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PubMed2006

Varying stable nitrogen isotope ratios of different coastal marsh plants and their relationships with wastewater nitrogen and land use in New England, USA.

The stable nitrogen isotope ratios of some biota have been used as indicators of sources of anthropogenic nitrogen. In this study the relationships of the stable nitrogen isotope ratios of marsh plants, Iva frutescens (L.), Phragmites australis (Cav.) Trin ex Steud, Spartina patens (Ait.) Muhl, Spartina alterniflora Loisel, Ulva lactuca (L.), and Enteromorpha intestinalis (L.) with wastewater nitrogen and land development in New England are described. Five of the six plant species (all but U. lactuca) showed significant relationships of increasing delta (15)N values with increasing wastewater nitrogen. There was a significant (P < 0.0001) downward shift in the delta (15)N of S. patens (6.0 +/- 0.48 per thousand) which is mycorrhizal compared with S. alterniflora (8.5 +/- 0.41 per thousand). The downward shift in delta (15)N may be caused by the assimilation of fixed nitrogen in the roots of S. patens. P. australis within sites had wide ranges of delta (15)N values, evidently influenced by the type of shoreline development or buffer at the upland border. In residential areas, the presence of a vegetated buffer (n = 24 locations) significantly (P < 0.001) reduced the delta (15)N (mean = 7.4 +/- 0.43 per thousand) of the P. australis compared to stands where there was no buffer (mean = 10.9 +/- 1.0 per thousand; n = 15). Among the plant species, I. frutescens located near the upland border showed the most significant (R (2) = 0.64; P = 0.006) inverse relationship with the percent agricultural land in the watershed. The delta (15)N of P. australis and I. frustescens is apparently an indicator of local inputs near the upland border, while the delta (15)N of Spartina relates with the integrated, watershed-sea nitrogen inputs.

Ecosystem↗
PubMed2006

Factors moderating children's adjustment to parental separation: findings from a community study in England.

Research findings show that there is marked variability in children's response to parental separation, but few studies identify the sources of this variation. This prospective longitudinal study examines the factors modifying children's adjustment to parental separation in a community sample of 5,635 families in England. Children's behavioral/emotional problems were assessed when children were aged 47 and 81 months; marital quality, maternal depression, socioeconomic circumstances, and demographic variables were assessed prior to the separation from maternal report. Results indicated that 346 mothers separated from their partners in the 3-year period. Preseparation differences were found for measures of family process and parent risk factors, with effect sizes ranging from small to trivial. Parental separation was associated with a significant but modest increase in behavioral/emotional problems, independent of marital quality, maternal depression, socioeconomic circumstances, and demographic variables. Moderation analyses showed that children of cohabiting parents had a greater increase in adjustment problems following parental separation than children of married parents. Further research elucidating the factors that moderate children's adjustment to parental separation is needed to improve our understanding of who may most likely benefit from preventive interventions.

Adaptation, Psychological↗
PubMed1994

Dietary differences in smokers and nonsmokers from two southeastern New England communities.

OBJECTIVE: Previous studies based on 24-hour dietary recall data have shown that smokers tend to consume less healthful diets than nonsmokers. We tested this hypothesis using data from food frequency questionnaires (FFQs) in a group of men and women. DESIGN: Characteristics of smokers and nonsmokers were compared using data collected from a cross-sectional household health survey. SUBJECTS: Adults aged 18 through 64 years from two communities in southeastern New England were randomly selected for the study and interviewed in their homes by trained personnel. The interview included questions on demographic and behavioral characteristics. Height, weight, blood pressure, and serum lipids were measured using standard protocols. The Willett FFQ was completed by 1,608 of 2,531 eligible respondents who made up our study sample. STATISTICAL ANALYSES PERFORMED: Respondents were categorized as current cigarette smokers or nonsmokers. Demographic, behavioral, physiologic, and dietary characteristics were compared between smokers and nonsmokers by analysis of covariance with age as the covariate. RESULTS: Eligible respondents who did not complete the FFQ differed from respondents with respect to age, gender, smoking prevalence, and several other demographic characteristics. Smokers consumed more energy, fat, alcohol, and caffeine than nonsmokers. Smoking status was inversely associated with intake of vitamins A and C, dietary fiber, folate, and iron among women, whereas differences were smaller and not significant among men. Women who smoked consumed fewer servings of fruits and vegetables than nonsmokers, but this trend was not noted in men. The association between diet and smoking was only slightly diminished by multivariate adjustment for age, income, regular exercise, marital status, and working status but most clinically relevant associations remained. The interaction between gender and smoking was not statistically significant for most dietary variables. CONCLUSIONS: These results suggest that health promotion messages targeted to smokers should include dietary instructions, especially for women.

Adult↗
PubMed1975

Results of pulmonary arterial banding in infancy. Survey of 5 years' experience in the New England Regional Infant Cardiac Program.

The results of pulmonary arterial banding in 238 infants, 12 percent of the infants admitted to the New England Regional Infant Cardiac Program, is reviewed. Overall survival to age 1 year was 63 percent. Survival was least likely (37 percent) in those who required banding within the 1st month of life. Additional surgery decreased the survival rate in those operated on after 1 month of age. Infants with anomalies for which no corrective surgical procedure is available (23 of 238) have only a 30 percent chance of survival. Those with lesions correctable within the 1st year (133 of 238) have a 74 percent survival rate; 52 percent (82 of 238) of those for whom a curative operation is available after the 1st year survive. These pulmonary arterial banding data coupled with results of primary correction should provide the data base required for an intelligent decision in respect to appropriate surgical treatment of infants with critical heart disease.

Heart Defects, Congenital↗
PubMed1990

Facial clefting in Kuwait and England: a comparative study.

A retrospective study of all new cases of facial clefts seen between January 1985 and December 1987 was carried out at the lbn Sina Hospital, Kuwait, and West Midlands Regional Plastic and Jaw Surgery Unit at Wordsley Hospital, Stourbridge, England; 234 arab children in Kuwait and 181 white Caucasian children in the West Midlands were studied. Despite vast differences in racial characteristics, environment and customs the pattern of clefting was very similar in the two groups. The incidence of clefts was calculated for the two regions and this demonstrated an increase in the incidence of cleft lip and palate (CL/P and CP) in the West Midlands since the last study was reported from this region in 1953.

Cleft Lip↗
PubMedDate not supplied

A field investigation of subclinical mastitis in sheep in southern England.

The prevalence, aetiology and epidemiological features of subclinical mastitis were investigated in 358 lowland ewes in seven flocks in southern England. Milk samples (2092) were collected at 3-weekly intervals; those which were both bacteriologically and Whiteside test positive were deemed to have originated from glands with subclinical mastitis. The period prevalence of subclinical mastitis was 11.7% and the prevalence remained relatively constant over the course of lactation (5.5-7.0%). The predominant bacterial isolates from 48 glands with subclinical mastitis were streptococci (42%), coagulase-negative staphylococci (33%), Pasteurella haemolytica (17%) and Staphylococcus aureus (8%). Coagulase-negative staphylococci were the predominant isolates (53%) from samples which did not show a positive Whiteside test result. The prevalence of subclinical mastitis increased with age of ewe but was not influenced by the presence of teat lesions. There was a significant association between the development of clinical mastitis (26 glands) and antecedent subclinical mastitis caused by the same organism (10 glands).

Animals↗
PubMed1980

The role of returned migrants in England's poorest region.

"Work on the growing international phenomenon of return migration requires a base of comparative knowledge on the less conspicuous process of inter-regional return migration. Three questionnaire studies in the North-East of England identified about one-quarter of respondents as 'returned migrants' to that region. This group [is] attracted to work in new factories, but their economic status has not been markedly improved by geographic mobility."

Demography↗
PubMed1989

Preventability of death from penetrating injury in England and Wales.

A total of 1000 deaths from injury in England and Wales have been reviewed to establish the incidence and pattern of penetrating injury and the adequacy of its management. Of the 1000 deaths, 71 (7.1 per cent) were due to penetrating injury. There were 32 knife wounds and 30 firearm injuries. Most of the latter were suicides. Only 17 patients (24 per cent) reached hospital alive. Of these cases, 10 had extracranial injury and all 10 deaths were considered to have been potentially preventable when reviewed by four external assessors. One of seven patients with cranial injury was considered to have been a potentially preventable death. The median age of the 11 cases of potentially preventable death was 37 years (range: 7-61 years). Of these, three did not have any surgery for surgically treatable injuries. Seven patients underwent operation and difficulty was encountered in six of these. It appears from our figures that whilst penetrating injury is an uncommon cause of death, it is poorly managed. The implications of this finding for systems of injury care in the United Kingdom are discussed.

Adolescent↗
PubMed1991

Where are they now? The career paths of graduates from post-registration degrees in nursing in England.

Degree courses for experienced nurses through part-time study are relatively new in Britain. The first course started in 1979, but their number has dramatically increased during the past decade, particularly in England. Due to this increase it is important that analysis of career paths of the graduates should occur. As no suitable questionnaire was found from the literature one was devised. Posting this to all graduates from three courses gave a response from 113 graduates (77.4%). Results showed graduates to be continuing in nursing. They showed life-long motivation to study and felt personal growth from the degree. Movement of graduates predominantly from clinical areas into nurse education was found.

Adult↗
PubMed1993

Ethical dilemmas in long-term care settings; interviews with nurses in Sweden and England.

With the aim of investigating ethical dilemmas arising in long-term care settings, nurses were interviewed at hospitals in southern Sweden and southern England. The interviews confirmed the occurrence of conflicts in caring for the elderly, and conflicts in the staff-patient-relative constellation. The content of the interviews was analysed with regard to prevailing principles of patient autonomy and the ranking order of preferences among those involved.

Conflict, Psychological↗
PubMed1995

The role of the continence adviser in England and Wales.

Continence advice in England and Wales is a relatively new specialism within nursing and, over the past 20 years, the number of continence advisers has grown substantially. There are, however, no formal qualifications for the role and the service has grown up in a piecemeal fashion. A study carried out by the Social Policy Research Unit of the University of York sought to answer basic quantitative questions about: (1) the number of continence advisers in post, their professional backgrounds and so on; (2) the structures within which continence advisers work; and (3) the nature of their current practice; as well as more attitudinal and developmental questions about the history and future development of continence advisers' work.

England↗
PubMed1982

The genetic contribution to multiple sclerosis. Evidence from North-East England.

A study of 206 patients with multiple sclerosis in the north-east of England and their families shows no evidence of monogenic involvement in the disorder. Much more likely is a multifactorial etiology in which the genetic component is polygenic. On this model the heritability is calculated at 52.1% or 40.9% if age variation in incidence is allowed for. The genetic component is present but no more then moderate in extent.

Adult↗
PubMed1975

Opportunist mycobacterial pulmonary infection and occupational dust exposure: an investigation in England and Wales.

This paper reports a study in England and Wales in which the industrial and non-industrial dust exposures and smoking habits of those whose pulmonary disease was due to opportunist mycobacterial infection were compared with a control group of similar age and same sex whose infection was with M. tuberculosis. Of 70 males, 53 were found to be infected with M. kansasi, 9 with M. xenopi, 6 with M. intracellulare and 2 with other opportunist mycobacteria. Only 8 females were found, of whom, 5 were infected with M. kansasi, and 3 with M. intracellulare, Those infected with M. kansasi were on average 6.5 years younger than those infected with other opportunist mycobacteria. There was no evidence of differences between patients infected with M. kansasi and their controls in various indices of past exposure to dust. A significantly higher proportion of patients infected with M. kansasi gave a history of current dust exposure at the time of diagnosis than patients infected with M. tuberculosis. There was an apparent association between infection with M. kansasi and exposure to the dusts of the metal grinding trades, but no association with a previous history of coal mining. The study suggests that the systematic establishment of the current occupations of all new patients suffering from disease due to M. kansasi should enable the occupations with high risk to be identified.

Adult↗
PubMed1976

Bacteriophage typing of Mycobacterium tuberculosis strains isolated in South East England.

The species Mycobacterium tuberculosis may be subdivided by its susceptibility to lysis by bacteriophages. In this study 300 strains have been typed with six phages to determine the prevalence of various phage types in South East England. The distribution of the phage types is considered in relation to the patients' racial origins and the clinical presentation of disease, whether pulmonary or extrapulmonary. The technical aspects of phage typing are described and modifications of existing techniques are discussed.

Bacteriophage Typing↗
PubMed1979

Infections with Mycobacterium malmoense in England and Wales.

Mycobacterium malmoense has been isolated from 11 patients in England and Wales. It was thought to be the cause of pulmonary disease in 9 of them and cervical adenitis in 2. The cultural and biochemical characters of the species are described and its position in relation to the avium-intracellulare complex and the non-chromogenicum-terrae-triviale complex determined by matching coefficients using 88 characters. Brief details are given of the 11 cases.

Aged↗
PubMed1981

A study of bovine strains of Mycobacterium tuberculosis isolated from humans in South-East England, 1977-1979.

Bovine strains of Mycobacterium tuberculosis were isolated from 137 of 5021 cases of tuberculosis (2.7%) occurring in South East England during the years 1977 to 1979. These were divisible into 'classical' and 'Afro-Asian' bovine strains according to their susceptibility to pyrazinamide. Classical strains were the predominant type among the Europeans and Afro-Asian types were commoner in immigrants. Bovine strains caused a high incidence of extrapulmonary disease in both ethnic groups and there was a significant relationship between renal disease and 'classical' strains. The age and sex distributions of bovine strains were similar to those of human strains in both ethnic groups. It was considered that these bovine strains were transmitted from human to human by the pulmonary route.

Adolescent↗
PubMed1984

Changes in tuberculosis notification rates in ethnic groups in England between 1971 and 1978/79.

Between special surveys in 1971 and 1978/79 the estimated annual tuberculosis notification rate for males in England fell from 30.5 per 100 000 to 22.6 per 100 000 (a decline of 3.8% per year). For females the rate fell from 18.4 per 100 000 to 15.8 per 100 000 (1.9% per year). In each survey the lowest rates were those for the white ethnic group born in the United Kingdom. The highest rates, some more than 50 times as great, occurred in immigrants from the Indian sub-continent (Indian or Pakistani/Bangladeshi). The rates for immigrants from the West Indies were 3 to 4 times as great as than those for the white group. The most rapid reductions in rate between the surveys, of about 10% per year, occurred in West Indian immigrants of both sexes and in Pakistani/Bangladeshi male immigrants. The rate for Pakistani/Bangladeshi females fell by 6.5% per year. For whites born in the U.K. the annual rate of decline was 5.1% in each sex. There was very little change for Indian immigrants of either sex. Between the surveys, continued immigration of groups from the Indian subcontinent with high notification rates considerably slowed the decline in notification rate for the whole population. The steep downward trend in notification rate for the white ethnic group may be expected to continue, but changes in the other ethnic groups are more difficult to assess because they are influenced by so many uncertain factors. In addition, the trends in the non-white ethnic groups born in the United Kingdom cannot yet be ascertained, but will become of increasing importance.

Bangladesh↗
PubMed1985

Mycobacterium malmoense in the north-east of England.

We report a 6 year experience (1979-1984) of isolating Mycobacterium malmoense in the north-east of England. Eleven subjects were involved of whom 10 had active infection--9 pulmonary, one cervical adenitis. The 11 new isolates represent 0.7% of all new mycobacterial isolates during this period and 10% of new non-tuberculous isolates. In all but 2 cases there was pre-existing pulmonary disease and/or a recognised predisposing factor to mycobacterial infection. The organisms were generally insensitive to isoniazid but sensitive to both rifampicin and ethionamide. The results of chemotherapy are described.

Adult↗