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At least 1,135 records · Page 63Linked to original sources
PubMed2005

Sequence of protein expression of bone sialoprotein and osteopontin at the developing interface between repair cementum and dentin in human deciduous teeth.

Experimental periodontal regeneration studies have revealed the weak binding of repair cementum to the root surface, whereas attachment of cementum to dentin preconditioned by odontoclasts appears to be superior. The aim of this study has been, therefore, to analyze the structural and partial biochemical nature of the interface that develops between resorbed dentin and repair cementum by using human deciduous teeth as a model. Aldehyde-fixed and decalcified tooth samples were embedded in acrylic or epoxy resins and sectioned for light and transmission electron microscopy. Antibodies against bone sialoprotein (BSP) and osteopontin (OPN), two noncollagenous proteins accumulating at hard tissue interfaces in bone and teeth, were used for protein A-gold immunocytochemistry. Light microscopy revealed a gradually increasing staining intensity of the external dentin matrix starting after the withdrawal of the odontoclast. Labeling for both BSP and OPN was first detected among the exposed collagen fibrils and in the intratubular dentin matrix when odontoclasts had withdrawn but mesenchymal cells were present. Subsequently, collagen fibrils of the repair cementum were deposited concomitantly with the appearance of labeling for BSP and OPN over the intratubular, intertubular, and peritubular dentin matrix. Labeled mineralization foci indicated the advancing mineralization front, and the collagenous repair matrix became integrated in an electron-dense organic material that showed labeling for BSP and OPN. Thus, no distinct planar interfacial matrix layer lies between the resorbed dentin and the repair cementum. The results suggest that odontoclasts precondition the dentin matrix such that the repair cementum becomes firmly attached.

Adolescent↗
PubMedDate not supplied

Caries experience and caries increments at 10 years of age.

The aim of the study was to examine the caries experience of 10-year-olds as measured with dmft/DMFT, to explain how caries increases by the age of 10 years, and which factors would explain caries increments. The setting was a representative population sample of first-born children in southwestern Finland. Dental health at 10 years of age was found to be good in 45%, fairly good in 40% and poor in 15% of the children. The caries index remained stable in 23% of carious children from 7 to 10 years of age. Daily consumption of sweets at the age of 3 years (OR 2.7; 95% CI 1.5-4.8; p < 0.001) was associated with a caries increment between 7 and 10 years of age (both deciduous and permanent teeth). This daily consumption of sweets and a child's late bedtime (OR 1.9; 95% CI 1.1--3.1; p = 0.023) were explanatory factors in the permanent teeth alone. In the deciduous teeth, mother's previous caries and child's earlier tooth brushing habits were explanatory factors of caries. As hypothesized, all five significant factors remaining in the final logistic regression analysis were family-related. Parental ability to care for and educate a child could be seen in dental health still at the age of 10 years. The family-related factors which were associated with caries should be emphasized much more comprehensively in everyday dental health care practice.

Age Factors↗
PubMed1989

Spacing in the human deciduous dentition in relation to tooth size and dental arch size.

Dental casts of 243 preschool children, 129 males and 114 females, aged 2.5-5.5 years, were analysed for the presence of interdental spaces, mesiodistal crown diameters, intercanine width, intermolar width and arch length (circumference). The prevalence of primate spaces (diastemata mesial to the upper canines and distal to the lowers) varied from 65 to 90% by arch and sex; it was lowest in the lower arch especially in females, and highest in the upper. These prevalences did not increase with age; however, other spaces which usually occur between incisors may develop towards the end of the deciduous dentition, commonly in arches with primate spaces. Generally, spacing of the deciduous anterior teeth was significantly related to mesiodistal crown diameter and intercanine arch width. The crowns were significantly broader and the arches significantly narrower in cases with no spaces than in those where spaces existed. As the genetic programming for tooth size also normally affects arch size, greater discrepancies between mesiodistal crown diameters of the deciduous anterior teeth and their permanent successors are probably associated with more deciduous arch spacing.

Age Factors↗