Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “NETHERLANDS”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,135 records · Page 63Linked to original sources
PubMed1998

[Increase in number of premature births in The Netherlands: comparison of 1983 and 1993. Scientific Guidance Commission of the National Neonatology Registration].

OBJECTIVE: Survey of changes in the number of preterm and very low birth weight infants in the Netherlands in ten years. DESIGN: Descriptive. SETTING: TNO Preventive en Gezondheid, sector Jeugd, Leiden, the Netherlands. METHODS: All infants with a gestational age less than 32 weeks and (or) a birth weight less than 1500 g from the National Neonatal Register born in 1993 were selected, supplemented with data from a questionnaire for hospitals not taking part in the register. The data were compared with those on similar infants from the 'Project on preterm and small for gestational age' infants born in 1983. RESULTS: The total number of preterm and very low birth weight infants increased from 1423 in 1983 to approximately 1882 in 1993. There was also an increase in terms of proportion, from 8.4 per thousand to 9.6 per thousand. The proportion of preterm infants never treated in a neonatal intensive care unit decreased from 40% in 1983 to 14% in 1993, probably due to increased centralization of neonatal intensive care facilities. In the same time mortality decreased for all gestational age categories. CONCLUSION: Both the total number and the survival of preterm and very low birth weight infants increased considerably over a decade. This caused a considerable increase in intensive care days and is therefore an important reason for the increased requirement of neonatal intensive care cots.

Female↗
PubMed1998

[Genetic carrier screening for hemoglobinopathies: the situation in the Netherlands compared with England].

In the Netherlands, in contrast to England, no screening for carriership of haemoglobinopathy (sickle-cell anaemia and thalassaemia) is being carried out. The absolute prevalence is low, but the prevalence in proportion to birth figures is approximately the same in the two countries. The lack of knowledge of the professional groups involved can be rectified by adequate instruction. The question whether screening should be carried out before pregnancy or early prenatally proved not difficult to solve in England. Screening for carriership is technically possible and in England it is also cost-effective. This screening should be performed in the Netherlands, as well.

Adult↗
PubMed1998

[Management of psoriasis in family practice is now in closer agreement with the guidelines of the Netherlands Society of Family Physicians].

OBJECTIVE: To assess changes in incidence of psoriasis and to study changes in the management of psoriasis in general practice after the sending of guidelines on management of psoriasis to general practitioners (GPs) by the NHG. DESIGN: Secondary data analysis. SETTING: Netherlands Institute for Health Care Research (NIVEL), Utrecht, the Netherlands. METHOD: Data on the incidence of psoriasis and its management by general practitioners were collected from a file predating the publication of the NHG guideline 'Psoriasis' in 1994, namely the 'Dutch National Survey of General Practice' (NS; 1987/'88), and from a subsequent file, the 'Registration Network Groningen' (RNG; 1995). RESULTS: In the NS there were 106 new patients with psoriasis (incidence: 1.3/1000/year; 95% confidence interval (95% CI): 1.2-1.4) while in the RNG there were 24 (incidence: 1.2/1000/year; 95% CI: 0.7-1.9). In all, there were 466 psoriasis patients in the NS and 125 in the RNG. The number of referrals to dermatologists was halved in 1995 (7.2%) compared with 1987/'88 (14.4%; p < 0.05). The most frequently prescribed dermatologica in psoriasis was in 1995 corticosteroid group 3 (32.8%; in 1987/'88: 28.5%), but the rise was stronger in corticosteroid group 2 (29.6%; in 1987/'88: 16.0%; p < 0.001) and group 4 (16.0%; in 1987/'88: 8.8%; p < 0.05). CONCLUSION: The incidence of psoriasis in general practice had not changed between 1987/'88 en 1995. Referral pattern and prescription shifted towards the guidelines issued by the NHG.

Adrenal Cortex Hormones↗
PubMed1998

[Increase of surgical day treatment in the Netherlands].

OBJECTIVE: To assess the quantitative development of day surgery in the Netherlands. DESIGN: Descriptive. SETTING: St. Antonius Hospital, Nieuwegein, the Netherlands. METHOD: Numbers of admissions in the period 1984-1995 were obtained from Dutch data bases of the National Hospital Institution (NZi). From SIG Health Care Information numbers were obtained with regard to seven specified interventions in the years 1991 to 1995, i.e. breast tumour excision, inguinal hernia repair, varicose vein operation, laparoscopic sterilisation, knee arthroscopy, cataract operation and tonsillectomy. The increase if any of the number of interventions in day care was determined by placing the hospitals in the order of decreasing proportions of day care, and subsequently applying the proportions of the 5th and 10th hospitals, respectively, to the whole group. RESULTS: The number of day care admissions rose from 172,000 (9.9% of all admissions) to 649,000 (29.1%). Of all interventions studied, the percentage carried out in day care increased; the percentages varied greatly from one hospital to another. In 1995, the mean number of interventions in daytime was 115,000 (57% of all 201,000 interventions). The shift from interventions during hospitalization to day care would be 42,000 and 51,000 (21% and 25% respectively, of 201,000), respectively; operations performed in day care would then amount to 166,000 (83% of the total number of interventions) and 157,000 (78%). CONCLUSION: Of the interventions studied, the proportion carried out in day care increased to 57%. In view of the intra- and interhospital differences, a considerable increase of day care in the near future is possible.

Adolescent↗
PubMedDate not supplied

Mortality due to unintentional injuries in The Netherlands, 1950-1995.

OBJECTIVE: To detect and explain changing trends in incidence, case fatality rates, and mortality for unintentional injuries in the Netherlands for the years 1950 through 1995. METHODS: Using national registry data, the authors analyzed trends in traffic injuries, occupational injuries, and home and leisure injuries. RESULTS: Between 1950 and 1970, mortality from unintentional injuries rose, reflecting an increasing incidence of injuries. This was followed by a sharp decline in mortality due to a decreasing incidence combined with a rapidly falling case fatality rate. Starting in the second half of the 1980s, the decline in mortality leveled off as the incidence of several injury subclasses once again rose. The observed trends reflect several background factors, including economic fluctuations (influencing exposure), preventive measures (reducing injury risk and injury severity), and improvements in trauma care (lowering the severity-adjusted case fatality rate). CONCLUSIONS: Injury mortality can be reduced through measures that lower injury risk, injury severity, or severity-adjusted case fatality rates. Beginning in the mid-1980s, such compensatory mechanisms have fallen short in the Netherlands. New policies are needed despite the impressive reductions in mortality already reached.

Accidents↗
PubMed1998

[Reciprocity and care of the elderly. An anthropologic comparison between Ghana and the Netherlands].

The author compares the lives of elderly people in Ghana and the Netherlands from the perspective of reciprocity. As a rule, the Ghanaian government does not provide social security for the elderly. Their security is entirely in the hands of their relatives and depends on reciprocity. As a result, some elderly find themselves in a stressful situation, both in material and in emotional terms. A remarkable similarity is that the principle of reciprocity is applied in both societies; in Ghana openly, in the Netherlands in a more subtle and concealed way.

Aged↗
PubMed1998

[A marked increase in the rate of diagnosed prostate cancer in the Netherlands during 1990-1996].

OBJECTIVE: To study the variation of the number of histologically detected adenocarcinomas of the prostate in the Netherlands during the period 1990-1996. DESIGN: Retrospective. SETTING: National study. METHOD: Use was made of data from the National Automated Morbid-Anatomical Record Department (PALGA), Utrecht. The following data were established for each year of the study period: the total number of histological examinations of the prostate, the number of men involved (often several histological examinations of the prostate of the same man in the same year), how often adenocarcinoma was diagnosed by these examinations and how many men were involved, as well as the age of all carcinoma patients. These data were compared with those concerning variation and incidence of cancer of the prostate obtained from the Netherlands. Cancer Registration and the Central Statistics Office. RESULTS: In 7 years a total of 205,525 histological examinations of the prostate were performed in 179,298 men; the diagnosis 'adenocarcinoma of the prostate' was made 52,964 times in 44,182 men. The number of tissue examinations with the diagnosis 'carcinoma of the prostate' increased by 63% (from 5,596 to 9,146), the number of men in whom this diagnosis was made increased by 62% (from 4,710 to 7,614). The relative frequency of prostate carcinoma in relation to all examinations of the prostate increased in 6 years (1991-1996) from 22% to 28%. In that period, the (uncorrected) incidence increased by 50%, while mortality corrected for age remained the same. CONCLUSION: Of the marked increase of the number of detected cases of carcinoma of the prostate in the study period, only a small part could be attributed to demographic changes. Since autopsies have shown that there exists a large 'stock' of subclinical carcinomas, most of the growth can probably be explained by the more intensive diagnostics with prostate-specific antigen and transrectal ultrasonography.

Adenocarcinoma↗
PubMed1998

[Migrane treatment in the Netherlands in the early twentieth century].

The treatment of migraine in the Netherlands underwent important changes in the beginning of the 20th century. Several factors played a role, including the development of analgesics (acetylsalicylic acid, phenacetin, and fampridine++) at the end of the 19th century. The introduction of phenobarbital for the treatment of epilepsy in 1912 resulted in prescription of this drug for migraine, because of the supposed similarities between both afflictions. Although ergotamine had been reported for the treatment of headache at the end of the 19th century and been recommended again during the 1920s, it appeared in the Dutch literature only at the end of the 1930s. Research abroad showed this drug to have vasoconstrictive properties in migraine, again confirming the vasogenic origin of the affliction. This is striking as vasodilating drugs had been prescribed for several years. The non-medical treatment largely remained as previously, notably the prescription of diets. The relation between migraine and anaphylaxis, based on research by the French school, was also investigated in the Netherlands and resulted in the prescription of diets to immunize against the proteins involved.

Analgesics↗
PubMed1976

[Review of the incidence of antibodies to various serological groups of the species Leptospira interrogans in a number of farm animals in the Netherlands (author's transl)].

Report on the results of serological studies on the species Leptospira interrogans in cattle (19,607), swine (6,348), dogs (182) and horses (88) from the Netherlands during the period from 1969 to 1974. Living cultures of the serotypes of pomona, icterohaemorrhagiae, canicola, guidae (Tarassovi serological group), grippotyphosa and sejroe were used as antigen in the micro-agglutination test. The numerical findings showed that antibodies to serotypes of the species Leptospira interrogans were present in 7.67 per cent of the cattle, 22.21 per cent of the pigs, 36.81 per cent of the dogs and 92.05 per cent of the horses studied. Infection with the serotypes of icterohaemorrhagiae and grippotyphosa was most common in cattle and horses, icterohaemorrhagiae and tarassovi were most common in swine and icterohaemorrhagiae and canicola were most common in dogs. The presence of pomona is not a factor in the Netherlands. In view of statistical findings, grippotyphosa infections in cattle may be assumed to result in abortion.

Abortion, Septic↗
PubMed1993

Antimicrobial drug use in hospitals in The Netherlands, Germany and Belgium.

Data on the use of antimicrobial drugs was collected by means of an inquiry to 30 hospitals in Belgium (15 in Dutch sectors and 15 in the French sectors), 21 hospitals in Germany and 20 hospitals in the Netherlands. The use of these drugs was expressed as the number of defined daily doses (DDD) per 100 bed days by the anatomical therapeutical chemical classification system. The total use of antimicrobial agents was significantly (p < 0.001) higher in both parts of Belgium (55.6 and 52.0 DDD per 100 bed days) than in Germany (37.9 DDD) or the Netherlands (34.1 DDD). In particular, amoxicillin-clavulanic acid, the first- and second-generation cephalosporins, aminoglycosides and fluoroquinolones were used more in Belgium than in either of the other countries. At least part of the differences observed in antimicrobial drug use could be explained by differences in written antibiotic policy.

Anti-Infective Agents↗
PubMed2006

Responders and non-responders in a study on medical end-of-life decisions in Denmark, the Netherlands, Sweden and Switzerland.

OBJECTIVES: To determine the direction and magnitude of participation bias in end-of-life research. METHODS: Within the framework of a European survey on medical end-of-life decisions, a non-response study was conducted among physicians in Denmark, the Netherlands, Sweden and Switzerland. People were asked about their attitudes and experiences in the area of medial end-of-life decision. The response rates ranged from 12.8% (Netherlands) to 39.4% (Switzerland). The responders (n = 5403) and the non-responders (n = 866) were compared regarding socio-demographic characteristics, experiences with terminal patients and agreement with attitudes towards "end-of-life decisions". The reasons for non-participation to the study were analyzed. RESULTS: Non-response did not cause socio-demographic distortion, but non-responders had statistically significantly fewer terminal patients than responders. Agreement rates were statistically significantly higher among responders than among non-responders for euthanasia, non-treatment decision and life-preserving statements. Neutral answers were statistically significantly more frequent among non-responders than among responders for life-preserving and euthanasia statements. The most commonly mentioned reason for non-participation was "lack of time". CONCLUSION: Non-participation does cause an overestimation of proponents of life-shortening, as well as of life-preserving end-of-life decisions. Non-responders more often have ambiguous attitudes towards end-of-life decisions than responders.

Adult↗
PubMed1970

Ergonomics around the world: the Netherlands.

This article, the third in a series, deals with ergonomics in the Netherlands. The membership of the Netherlands Ergonomics Society is discussed and ergonomics groups within industry are detailed with some of the work carried out. Four institutes which have ergonomics interests are given; also the available sources of education in the field.

Journal Article↗
PubMed1997

Genotypic diversity of Campylobacter lari isolated from mussels and oysters in The Netherlands.

In order to gain insight into the epidemiology of Campylobacter lari infection in The Netherlands due to the consumption of raw mussels and oysters, batches of these shellfish were screened for the presence of Campylobacter spp. during a 6 month period in 1993-1994. Apparently, 41 out of 59 batches of mussels and 11 out of 41 batches of oysters were colonized with Campylobacter spp. A subset of the isolates was further characterized by additional phenotypic tests, numerical analysis of electrophoretic protein patterns, and genotyping by random amplification of polymorphic DNA (RAPD). Protein electrophoretic analysis of 39 Campylobacter spp. cultured from 24 batches of mussels and oysters, revealed that all isolates, except two, were C. lari. Two strains with an aberrant protein pattern were identified as C. coli and C. hyointestinalis, respectively. Nalidixic acid susceptible campylobacters (NASC) and urease-positive thermophylic campylobacters (UPTC) did not form separate clusters and should be considered biovars only. Several strains were both urease positive and nalidixic acid susceptible, which represents a new biovar within C. lari. The results of RAPD demonstrated the presence of 3 distinct genetic variants, implying that even within a single batch of shell fish, relatively extensive DNA polymorphisms can be found. It is therefore apparent that this complex group of C. lari is characterized by a high degree of genetic diversity, implying the presence of a heterogenous population of C. lari in crustacean organisms living in marine waters in a restricted area in The Netherlands.

Animals↗
PubMed1999

Workload, capacity for coping and psychological and physical outcomes amongst home helps in the Netherlands.

Owing to many developments and changes in home care in the Netherlands, a national study was carried out. One of the aims was to examine the differences between the six categories of home help in the Netherlands regarding workload, pressure of work and capacity for coping. A total of 474 home helps from six categories participated in the study. A structured questionnaire, based on the components of the research model, was used, which consisted of existing scales regarding workload (organizational and job characteristics, working conditions), psychological and physical outcomes (job satisfaction, burnout, health) and capacity for coping (social support, leadership style, coping strategies). Workload, specifically organizational and job characteristics are scored low by alpha helps and, to a lesser degree, by A home helps. The higher categories of home help experienced relatively bad working conditions. Home helps, except for alpha helps, are, on the whole, quite satisfied with their work, which is one of the psychological and physical outcomes. The higher categories of home help (C, D and E carers) experienced high feelings of emotional exhaustion. Health, absenteeism and back problems did not differ significantly amongst home helps. When looking at capacity for coping, traditional home helps (A to E) received more social support. The subordinate categories of home help dealt less actively with their problems and sought less social support than the other categories. Alpha helps are not employed by the organization and this might cause low organizational and job characteristics, and little social support. Their satisfaction scores suggest that they would like to see their low organizational involvement changed. The higher categories of home help, who carry out many psychosocial tasks, have higher emotional and mental workload and high burnout scores. B, C and D carers, who perform personal care and have to adhere to strict planning, experience extreme time pressure and a high physical workload.

Journal Article↗
PubMed2004

Feasibility of central co-ordinated EMA/CO for gestational trophoblastic disease in the Netherlands.

OBJECTIVE: In the Netherlands, high risk gestational trophoblastic disease (GTD) patients are treated in different referral hospitals with a national working party on trophoblastic tumours having a co-ordinating function. Our purpose was to evaluate whether this policy is a satisfactory alternative to complete centralisation. DESIGN: A retrospective study of all etoposide, methotrexate, actomycin D, cyclophosphamide and vincristine (EMA/CO)-treated women in the Netherlands between 1986 and 1997. Data regarding risk factors, treatment results and toxicity were collected. SETTING: Ten hospitals; 2 general, 6 academical and 2 oncology centres. POPULATION: Fifty EMA/CO-treated women registered by the central registration unit of the Dutch Working Party on Trophoblastic Disease. METHODS: Patients files and quarterly reports of the Dutch Working Party. MAIN OUTCOME MEASURES: Cure rate and consistency of treatment in different hospitals. RESULTS: EMA/CO treatment was administered in 10 different hospitals. All patients were discussed during the meetings of the Dutch Working Party and overall, 86% of patients were cured. Consistency in treatment was good. CONCLUSIONS: Cure rates were comparable with results of single institution series. We conclude that treatment of high risk GTD patients in different referral hospitals with concentration of expertise in a working party is a good alternative to centralisation of treatment in GTD specialised hospitals.

Adult↗
PubMed1999

Human papillomavirus in malignant cervical lesions in Surinam, a high-risk country, compared to the Netherlands, a low-risk country.

In various countries epidemiologic studies show an association between human papillomavirus (HPV) and cancer of the uterine cervix. We determined the presence of HPV and the distribution of the different HPV genotypes in cervical carcinomas from Surinam, a high-incidence country. The results were compared to the Netherlands where the incidence is five times lower. One hundred thirty cervical carcinomas from patients in Surinam were randomly selected and compared to an unselected group of 128 cervical carcinomas from caucasoid Dutch patients. Presence of HPV and distribution of HPV genotypes was determined in DNA extracted from paraffin-embedded specimens by polymerase chain reaction and sequence analysis. HPV DNA was detected in 82% of the Surinamese cervical cancer patients and in 87% of the Dutch patients. Thirteen different HPV genotypes were detected in the Surinamese group, and nine different HPV genotypes were detected in the Dutch group. Among the HPV-positive samples, HPV 16 was present in 68% in the Netherlands compared to only 49% in Surinam, where less common genotypes such as HPV 35, 45, and 58 were more prevalent. The results show a strong association between HPV and cervical cancer in both groups. However, the observed significant variation in distribution of the genotypes in the two populations with a large difference in cervical carcinoma incidence is important to the general understanding of the etiology of cervical cancer and to the development of HPV vaccination strategies.

Journal Article↗
PubMed2001

Cardiovascular risk factors and 10-year all-cause mortality in elderly European male populations; the FINE study. Finland, Italy, Netherlands, Elderly.

BACKGROUND: This study aims to examine cardiovascular risk factors in relation to all-cause mortality in elderly populations of different European countries. METHODS: Men aged 65--84 years from defined administrative areas were enrolled in Finland (rural areas of east and west Finland; n=716), in the Netherlands (the town of Zutphen; n=887), and in Italy (the rural areas of Crevalcore and Montegiorgio; n=682). Ten-year all-cause mortality was studied in relation to measurements taken at entry: age, systolic blood pressure, HDL- and non-HDL-cholesterol, body mass index, heart rate and smoking habits. Univariate and multivariate analyses were performed with all-cause mortality as the end-point. RESULTS: Ten-year death rates from all causes were higher in Finland (574 per 1000), lower in the Netherlands (475 per 1000), and Italy (466 per 1000). Age, heart rate and smoking in all three countries were independently associated with 10-year all-cause mortality. Non-HDL-cholesterol was not related with all-cause mortality. The observed associations between HDL-cholesterol, systolic blood pressure, body mass index and all-cause mortality were dependent on the in- or exclusions of early death. CONCLUSION: In these elderly men only age, smoking habits and heart rate were consistently associated with all-cause mortality.

Age Factors↗
PubMed2001

Energy restriction in childhood and adolescence and risk of prostate cancer: results from the Netherlands Cohort Study.

This study investigated the association between prostate cancer risk and energy restriction during childhood. The authors examined the hypothesis among 58,279 men aged 55-69 years enrolled in the Netherlands Cohort Study on Diet and Cancer. Information on diet and risk factors was collected by questionnaire in 1986. Additional information was collected on residence during the Dutch Hunger Winter (1944-1945) and the World War II years (1940-1944) and father's employment status during the economic depression of 1932-1940, used as indicators of exposure. A case-cohort approach was used. After 7.3 years of follow-up (through December 1993), 903 prostate cancer cases were available for analysis. Analyses were carried out for all prostate cancer cases. The prostate cancer rate ratio for men who had lived in a western Netherlands city in 1944-1945 was 1.15 (95% confidence interval (CI): 0.80, 1.31), and the rate ratio for men who had lived in a western rural area in 1944-1945 was 1.30 (95% CI: 0.97, 1.73). Residence during the war years (1940-1944) and father's employment in 1932-1940 showed no relation to prostate cancer risk. In subgroup analyses in which exposure before, during, and after the adolescent growth spurt was evaluated, the same pattern as that of the overall data was shown. The authors found no evidence for the hypothesis that energy restriction early in life decreases prostate cancer risk later in life.

Aged↗