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[A monitoring system for occupational cancer].

INTRODUCTION: The Italian Occupation and Safety Act (d.lgs 626/94) provided for the establishment of a nationwide occupational cancer registry, under the National Institute for Occupational Health and Safety (ISPESL), with the aim of detecting cancer cases of occupational origin and estimating the influence of occupation in cancer causation. METHODS: Information on cancer cases, drawn from six Italian population-based cancer registries (CRs of Friuli Venezia Giulia Region, Genoa Town and Genoa Province, Macerata Town, Umbria Region, Varese Town, Veneto Region), and on a random sample of population controls selected in each CRs area were linked with data on subjects employed in private enterprises that have been available in electronic form since 1974 at the National Institute for Social Security (INPS). In this way, both for cases and controls, the occupational histories of past employment were collected. A population-based case-control study covering the period 1990-1998 was carried out with the aim of estimating occupational cancer risk in the private sector by site and economic category in each area. Since one of the major drawbacks of this approach is the difficulty in distinguishing true occupational hazards from incidental findings derived from multiple comparisons, an extensive research of occupational literature was carried out, independently of the study results, to compare our results with existing knowledge on occupational risks. RESULTS: Pooled analysis of the most recent incidence data based on 36,379 cases and 29,572 controls was performed; 34 "statistically significant" associations were found for 11 economic categories. Using our literature review, 10 associations were supported by more than 5 publishedpapers, 14 by a number of papers between 1 and 5, and 10 associations had not been previously reported. CONCLUSIONS: This system appears suitable for assessing existing occupational cancer risks and can eventually lead to detecting occupational hazards in many areas of Italy. The system can also provide a list of cases suitable for in-depth search for past occupational exposures.

Adult↗

Activated sludge image analysis system: monitoring settleability and effluent clarity.

A fully automized image analysis procedure is presented for fast and reliable characterization of the activated sludge composition. In previous research, relations between filament abundance and floc shape on the one hand, and the Sludge Volume Index on the other hand were sought. This work aims at demonstrating the use of the image analysis information as an indication for the amount of suspended solids in the effluent.

Automation↗

Possible applications of drug prescription monitoring systems in Italy.

Numerous experiences have already been implemented as regards the use of data concerning drug prescriptions and relative expenditure. This article focuses firstly on how such data are used from an administrative point of view in the Veneto Region, and secondly on the cultural and scientific aspects involved. The supply of feedback to general practitioners (GPs) with drug prescription indicators has made possible to cut down farmaceutical expenditure. Moreover, the analysis of the substances used by the GPs highlights the areas which require special attention in order to improve the quality of prescription.

Budgets↗

Single-mouse urine collection and pH monitoring system.

A glass cage with minimal surface area was designed and used to house mice for 24-hour urine collections. An experiment was performed with a radio-labeled compound excreted in the urine to assess the collection efficiency of the cage. In this experiment 74.2 +/- 6.5% of the excreted radioactivity was recovered in the urine, with 25.8 +/- 6.5% found adhering to the cage surfaces. When a flow-through pH electrode, meter, and recorder were attached, the system provided a continuous pH versus time urination record.

Animals↗

[Epidemiologic aspects of Campylobacter infection in hospitalized children. Evaluation of an national monitoring system].

Among the data collected by the national system for the surveillance of Campylobacter infections, those concerning hospitalized children are described. During 1986 and 1987, 508 cases were reported. Among the 466 strains studied, 74% were C. jejuni strains. There were only four strains of C. fetus. All the isolates except nine were recovered from stools. Diarrhea was the most prominent symptom. Patients were more likely to be males and infants. Infections were more frequent in late summer.

Adolescent↗