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[Contact allergy to olive oil].

Sensitization to olive oils has not yet been reported in the German literature. A 43 year old female developed increasing eczematous reactions after treatment of her leg with a boric acid/zinc oxide preparation in an oil vehicle. When different components of this zinc oxide/oil compound were tested, olive oil proved positive. A patch testing with other vegetable oils gave negative results.

Adult↗

[Contact allergy to dexpanthenol].

A case report is given of a 56-year-old female patient with a postthrombotic leg ulcer and stasis dermatitis, in whom contact dermatitis to a dexpanthenol-containing ointment was first described in 1965. Recent allergy testing confirmed this finding and revealed positive reactions to the pure substance dexpanthenol as well as to two additives. Based on this case history the importance of dexpanthenol as an allergen is discussed.

Drug Eruptions↗

Lower extremity purpura.

Purpura refers to pigmented eruptions that are recognized dermatologically. Their clinical appearance is valuable in identifying an appropriate etiology. The author discusses this entity and reviews differential diagnoses.

Diagnosis, Differential↗

Atrophie blanche in chronic myelogenous leukemia.

Atrophie blanche is a syndrome of painful vasculitic infarctive lesions of the lower extremities that heal leaving characteristic atrophic, porcelain white scars. The syndrome may occur as an idiopathic entity or associated with various hematologic and collagen vascular disorders. We present the first recognized case of atrophie blanche in a patient with chronic myelogenous leukemia. This presentation may be part of the expanding spectrum of nonspecific cutaneous manifestations of leukemia (leukemids).

Aged↗

The role of patch testing in stasis dermatitis.

Stasis dermatitis, a chronic varicose inflammation of the skin of the lower legs, frequently is complicated by the development of contact hypersensitivity. This retrospective study of forty-six patients with stasis dermatitis found a 60.9 percent incidence of at least one significantly positive patch test reaction. The two allergens that elicited positive reactions most commonly were neomycin and epoxy resin. These results and those of other authors reinforce our contention that patch testing should be a part of the routine work-up of patients with stasis dermatitis.

Dermatitis, Contact↗