Studies on radioactive iodination of fluorescein isothiocyanate.
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A rapid, reproducible method for the production of specifically labeled anti-Dirofilaria immitis microfilaria (MFF) globulins (MAG) has been devised. These labeled antibodies have made the detection of D immitis in serum possible by a fluorescent-antibody technique.
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A number of (N-aryl-dithiocarbamino)-alkanecarbonic acids bearing halogen substituents and related compounds are described which may be considered potential isothicyanate forming substances. The in vitro fungistatic activity of these compounds was investigated and the results obtained compared with those of captan and thiram. It was demonstrated that the halogen substituted (N-aryl)-dithiocarbamino)-alkanecarbonic acids exert an intensive fungistatic effect with a wide spectrum of activity and that the most active of them are equal to captan and thiram.