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At least 1,135 records · Page 63Linked to original sources
PubMed1987

[Preoperative embolization with gelfoam powder for intracranial meningioma causing unusual peritumoral hemorrhage--with reference to the mechanism of hemorrhage].

Preoperative embolization for intracranial meningioma has been performed at many institutions and its effectiveness has been well recognized. The complications of embolization such as facial pain, fever and facial nerve palsy, et al, were mild and temporary except embolus migration into intracranial vessels, but a peritumoral hemorrhage due to preoperative embolization was extremely rare. Recently we have experienced such an unusual complication, then we describe this complication here and discuss the mechanism of hemorrhage briefly. A 73-year-old female who had the left falx meningioma underwent preoperative embolization with gelfoam powder through the transfemoral route. About 10 hours later, she developed disturbance of consciousness and right hemiplegia. At that time, CT scan showed peritumoral hemorrhage and an increase in midline shift. An emergency craniotomy was performed and total removal of the falx meningioma (Simpson grade II) and evacuation of the hematoma were done. The postoperative course was uneventful. We conclude that gelfoam powder (average particle size 40-60 mu) is a useful material for preoperative embolization but may at times cause peritumoral hemorrhage.

Aged↗
PubMed1985

Percutaneous transcatheter embolization for arterial trauma.

With increasing technologic advances in interventional radiology, the vascular surgeon should be well versed in the indications, limitations, complications, and results of percutaneous transcatheter embolization for arterial trauma. Three hundred twenty-eight angiographically determined arterial injuries occurred in 242 patients from 1977 to 1984 in a major city hospital trauma center and were studied prospectively. Transcatheter embolizations performed for 107 arterial injuries in 100 patients were successful in 82.2% of injuries. Gelfoam, minicoils, microcoils, intimal dissections, or a combination of modalities was utilized. Anterior and posterior element pelvic fractures associated with hypotension and transfusion of 6 units or more of blood required embolization in 28 patients. Bleeding was controlled in 85.7% of patients. Percutaneous transcatheter embolization was also effective in controlling 84.2% of arteriovenous fistulas, 88.9% of penetrating neck arterial injuries, and 73.3% of postoperative intra-abdominal hemorrhage. Therapeutic transcatheter embolization is a valuable adjunct to the vascular surgeon dealing with the spectrum of vascular trauma.

Arteries↗
PubMed1985

[Conservative therapy of upper gastrointestinal hemorrhage (prospective, randomized, controlled)].

In this prospective study for pharmacotherapy of non varicial upper gastrointestinal haemorrhage eight therapy groups were examined. The efficacy of the most important drugs for ulcus disease was considered. The drugs were used alone and in combination. The results indicated no favourable effect of one preparation (Cimetidine, Pirenzepine, Ranitidine). Significant benefit for the long time healing rate was noted among the combination therapies, especially with Sucralfate, which was not used alone.

Aluminum↗
PubMed1985

Embolization of renal carcinoma. Comparison between the early results of Gelfoam and absolute ethanol embolization.

In a series 49 embolizations of 30 renal carcinomas, of which 21 were later nephrectomized, the early results of embolization with Gelfoam or absolute ethanol were compared. Embolization with absolute ethanol, using Citanest renal anaesthesia and a balloon occlusion catheter was significantly (p less than 0.001) more effective, and also caused significantly (p less than 0.05) less nausea or vomiting and almost significantly (p less than 0.10) less pain, compared with Gelfoam embolization.

Aged↗
PubMed1986

[Significance of temporary injection into the lining of the vocal cords in the treatment of paralytic dysphonia].

We report on our clinical experience with the so-called temporary injection of the vocal cords by means of gelatin paste (Gelfoam) application, performed on 24 patients. In a fairly high percentage of patients we noted a long-lasting positive result in respect of vocal performance, despite persisting vocal cord paresis. It is believed that in such cases the relatively slow absorption of the gelatin paste creates favourable conditions for spontaneous phonatory compensation.

Follow-Up Studies↗
PubMed1985

Transcatheter embolization of the dorsal pancreatic artery to control massive postoperative bleeding.

We report a severely traumatized patient who developed massive bleeding through surgical drains in the postoperative period. Superselective dorsal pancreatic arteriography demonstrated extravasation of contrast material in the pancreatic bed. Embolization with Gel-foam particles successfully controlled this severe bleeding. Transcatheter embolization is the procedure of choice for controlling pancreatic bleeding in acutely traumatized patients.

Abdominal Injuries↗
PubMed1985

Preoperative Gelfoam embolization of supratentorial meningiomas.

Intracranial meningiomas are often highly vascular and a successful outcome depends upon surgical resection. Preoperative embolization of supratentorial meningiomas, which have a major blood supply from the external carotid artery, has been advocated to reduce intraoperative bleeding and thus facilitate surgical extirpation. The authors carried out transfemoral, Gelfoam embolization preoperatively in eight patients with supratentorial meningiomas. In seven of the cases, post-embolization, contrast-enhanced, computerized tomography was carried out. Areas of low-density tumour necrosis were identified in five. In three of the eight patients, post-embolization angiography demonstrated elimination of the tumour blush and in the other five, the blush was reduced in intensity. Histologic evidence of tumour embolization was identified in each case to a varying degree. Preoperative embolization resulted in an identifiable radiologic change in the majority of these tumours, but the authors could not determine, in this small series, whether intraoperative bleeding was reduced.

Adult↗
PubMedDate not supplied

Localization of therapeutic gelatin emboli using radiolabeling--an experimental study.

Transcatheter embolization has recently gained widespread acceptance in the treatment of a variety of conditions. To clarify the localization of therapeutic gelatin particles, we have described a simple and safe technique of labeling gelatin particles with 99mTc using stannous chloride solution. This technique provides satisfactory labeling efficiency and allows excellent scintigraphic images of therapeutic gelatin emboli, thus making it possible to clarify the localization of the injected embolic material in vivo.

Animals↗
PubMed1973

In vitro characteristics of human glioblastomas maintained in organ culture systems. Light microscopy observations.

Light microscopy observations are described on five human glioblastomas grown in organ culture systems, using either a three-dimensional sponge foam matrix technic or a Millipore filter platform technic. Many cultures were successfully maintained for more than 2 months; one was maintained for 137 days. Invasion of the sponge foam matrix by glioma cells was invariably demonstrated. Mitotic figures were seen up to 122 days after explantation. All tumors showed the development of well-differentiated astrocytes; they often showed increased glial fibrillogenesis in the later stages of culture. Oligodendroglia were also demonstrated in one case. The in vivo features of pseudopalisading and endothelial proliferation were not seen. On the contrary, the vascular stroma of several explants showed a marked tendency to undergo sclerosis, with thickening, hyalinization and gradual obliteration of the vascular lumens. The cultural behavior of the explants with this technic was compared with that of sister cultures grown on collagen-coated coverslips. The organ culture technics revealed some important differences in growth characteristics. In contrast to what was seen in collagen-coated coverslip cultures, fibroblastic proliferation was inhibited, and the marked anaplastic cellular features that were sometimes manifest after 4 to 6 weeks on coated coverslips were not seen in the organ cultures.

Adult↗