New multidrug regimen with indigenous drugs and dapsone in the treatment of lepromatous leprosy (preliminary report).
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Animals↗
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A rapid test for bacillary resistance to dapsone.
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Clofazimine↗
The killing of Mycobacterium leprae in mice by various dietary concentrations of dapsone and rifampicin.
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Animals↗
[Dynamics of establishing resistance of M. leprae to dapsone and rifampicin in Martinique].
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Adult↗
Effect of clofazimine and dapsone on rifampicin (Lositril) pharmacokinetics in multibacillary and paucibacillary leprosy cases.
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Adolescent↗
[Do existing preclinical studies with dapsone support its use in short-term chemotherapy of tuberculosis in economically developed countries?].
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Animals↗
Diabetogenic effect of dapsone.
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Dapsone↗
Oily injections of dapsone; an acceptable form of treatment?
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Adolescent↗
In vitro study of the effect of dapsone on the components of the peripheral nerve in organised nerve culture model.
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Animals↗
Therapeutic effects of adding rimactane (rifampicin) 450 milligrams daily or 1200 milligrams once monthly in a single dose to dapsone 50 milligrams daily in patients with lepromatous leprosy.
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Adolescent↗
[A case of disseminated miliary lupus of the face treated with dapsone].
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Adult↗
Blood dapsone levels in leprosy patients treated with acedapsone.
The metabolism of the repository drug acedapsone (DADDS,4,4'-diacetyldiaminodiphenyl sulfone) was studied in 15 individuals receiving 225 mg of DADDS, intramuscularly for a period of 75 days. Plasma levels of DDS were determined on the 2nd, 7th, 15th, 30th, 60th and 75th day after administration of the drug by spectrophoto-fluorometric technique. The mean peak levels of DDS (85.36 ng/ml) were noticed on 7th day followed by a gradual decrease in DDS concentration. The mean half-life level (44.53 ng/ml) of DDS were observed around the 15th day. The mean DDS level for the entire period of observation after one dose was 41.95 ng/ml. On the 75th day, the DDS level reached the minimum value of 14.76 ng/ml which was still about 5 times more than the minimal inhibitory concentration (MIC) level of DDS against M. leprae (3 ng/ml). The results are discussed.
Acedapsone↗
The dapsone syndrome. A case report.
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Adult↗
On urine spot test for dapsone intake.
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Dapsone↗
Do leprosy patients in Papua New Guinea take their dapsone?
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Dapsone↗
Dapsone in the treatment of presumed brown recluse spider bite of the eyelid.
Brown recluse spider bites occur commonly in the Southern United States but eyelid bites are rare. Management of eyelid bites is difficult because the initial spider bite is frequently unnoticed, surgical and medical treatments are ineffective, and even a small area of necrosis affects the appearance and function of the eyelid.
Adult↗