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Results for “DERMATITIS, CONTACT”

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At least 1,135 records · Page 63Linked to original sources
PubMed2003

Corticotropin-releasing factor receptor type 1 is involved in the stress-induced exacerbation of chronic contact dermatitis in rats.

Cutaneous diseases such as psoriasis and atopic dermatitis are worsened by psychic stress. We attempted to clarify the involvement of the corticotropin-releasing factor (CRF) receptor (CRFR) in stress-induced exacerbation of chronic contact dermatitis in rats. Male Wistar rats, in which chronic contact dermatitis had been induced by 2,4,6-trinitro-1-chlorobenzene (TNCB), were exposed to a 1-h period of electric foot-shock following intraperitoneal administration of CRA1000, a selective CRFR type 1 (CRFR1) antagonist, or vehicle everyday for 9 days. Histological examination of the skin showed that the epidermis significantly thickened and the number of mast cells in the dermis significantly increased by repeated exposure to stress, and that these changes were blocked by CRA1000. These results suggest that CRFR1 is involved in the stress-induced exacerbation of chronic contact dermatitis.

Animals↗
PubMed2006

Skin care in occupational contact dermatitis of the hands.

A survey of patients attending an occupational dermatology clinic with suspected occupational contact dermatitis affecting the hands was undertaken to determine if optimal skin care treatment had been instituted prior to referral for patch testing. Appropriate treatment for contact dermatitis of the hands was defined as concurrent use of a soap substitute, use of a lipid-rich moisturizer, and if appropriate, use of a topical corticosteroid in an ointment vehicle. Patients were asked about the use of a particular soap substitute, the name and type of any moisturizer used and the name and type of topical corticosteroids currently used. The products were examined where possible. Only one-third of all patients were using the complete package at the time of their clinic appointment. Nearly all of these patients had seen a dermatologist prior to this appointment. Of the group of patients with work-related diseases who reported having seen a dermatologist prior to the clinic appointment, only 38% were using the complete skin care routine.

Administration, Cutaneous↗
PubMed1999

Allergic contact dermatitis caused by dialkyl thioureas in a patient with sleep apnea.

Allergic contact dermatitis of the scalp is relatively uncommon. This is a case report of a patient with chronic scalp dermatitis in the distribution of his continuous positive airway pressure (CPAP) mask neoprene rubber strap. Our objective was to identify any relevant contact allergens. Patch testing to the North American Contact Dermatitis Group (NACDG) Standard Allergens, a series of supplemental rubber allergens, and a sample of the neoprene from the patient's mask strap was performed. Relevant allergies to dialkyl thioureas, and the neoprene rubber portion of the CPAP mask strap were identified. Replacement with a cloth strap resulted in clearing of the dermatitis.

Dermatitis, Allergic Contact↗
PubMed1986

Contact dermatitis in hairdressers.

18 cases of hand dermatitis in hairdressers seen over a 5-year period are reviewed. The diagnoses in these patients are discussed with reference to other studies of hand dermatitis in hairdressers. Contact allergy due to paraphenylenediamine and related hair dyes was the presenting complaint in younger hairdressers, while formaldehyde allergy occurred in those who were older. The prognosis in the former group of workers with respect to continued employment in the trade tended to be poorer than the latter. Follow-up revealed that hand dermatitis often resulted in the worker not continuing to work in the hairdressing trade.

Adult↗
PubMed2001

Allergic contact dermatitis and its relationship to carcinogenicity.

The relationship between allergic contact dermatitis (ACD) and carcinogenicity was investigated using a recently developed and validated simulation approach. The analyses indicated that while there are electrophilic and non-electrophilic components to ACD, these were not identical to those operating in carcinogenicity. Accordingly, with respect to carcinogenicity prediction, the results of ACD do not improve the results based upon mutagenicity testing alone, the latter being a surrogate for potential electrophilicity.

Animals↗
PubMed1984

Allergic contact dermatitis to a colophony derivative.

5 patients developed acute allergic contact dermatitis to a wood rosin present in the adhesive of tapes used to approximate the edges of incisions. The exposure history consistently included application after an orthopedic procedure with subsequent occlusion under a cast for 3 weeks.

Adolescent↗
PubMed1986

Contact dermatitis to antituberculosis drugs.

The literature has been reviewed for contact dermatitis occurring to antituberculosis agents. Of the 12 known drugs, 6 (isoniazid, rifampicin, ethambutol, para-aminosalicylic acid, streptomycin and kanamycin) have been documented by patch test to cause this type of dermatitis in certain individuals. Cross sensitization has been observed to contribute significantly to the allergic reactions noted from isoniazid, streptomycin, and kanamycin. Hyposensitization has also been discussed in this review.

Aminosalicylic Acid↗