Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Computer Programs And Programming”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,135 records · Page 63Linked to original sources
PubMed1990

MORFOREL, a computer program for two-dimensional analysis of micrographs of biological specimens, with emphasis on immunogold preparations.

The program is a tool for accelerating analysis of tissue components (profiles) as seen in micrographs, including electron micrographs with immunoreactive substances labelled with gold particles. Required equipment is a computer with digitizer and printer. From coordinates sampled around the profiles, area, perimeter and form factor are calculated; particles in profiles, when wanted, are counted to obtain particle densities. MORFOREL permits basic statistical calculations on primary data or on composite expressions based on them. Expressions can be saved on disk and retrieved. Primary and calculated data are readily output in a format readable by common commercial packages.

Cerebral Cortex↗
PubMed1985

Analysis of radioligand binding experiments. A collection of computer programs for the IBM PC.

It is now well accepted that graphic methods are a poor choice of analytical technique for analyzing radioligand binding data given the complexity of some radioligand-binding sites interactions; this is true not only for studies performed at equilibrium but also for those examining kinetic properties of the radioligand. As a consequence the computer plays an important role in all forms of radioligand binding experiments because it reduces the labor-intensive calculations associated with such experiments and it allows the use of more appropriate weighted nonlinear curve-fitting techniques that more accurately describe the radioligand-binding site interaction. This paper describes a collection of four programs (KINETIC, EBDA, LIGAND, and LOWRY) that can be used to analyze most forms of radioligand binding experiments. The programs have been adapted for use on an IBM PC, which is a popular, inexpensive microcomputer and which is well suited to the analysis of radioligand binding data.

Animals↗
PubMed1987

A simple computer program for generating person-time data in cohort studies involving time-related factors.

The use of grouped data methods, such as standardized rate ratios and Poisson regression, for the analysis of cohort studies has a number of attractive features. This approach, however, has not been widely used in the past because of the difficulty of generating person-time data required for the computation of rates, particularly when stratification on time-related factors is involved. This paper presents a simple Statistical Analysis System (SAS) program for the generation of such data in a form that can be read directly by GLIM and used in a Poisson regression analysis. In addition to its simplicity, the program has the advantage of considerable flexibility and involves no restrictions on the number of time-related factors or the number of levels of each factor. Furthermore, it can be modified easily for multiple disease outcomes and for analyses of the latency period, or empirical induction time.

Humans↗
PubMed1982

Iterative weighted regression analysis of logit responses: a computer program for analysis of bioassays and immunoassays.

A program, WRANL, is described for the analysis of immunoassays or bioassays which have a logistic dose-response relationship. Responses are transformed to logits and iterative weighted regression analysis is used to obtain log dose-logit response lines for all preparations compared in an assay. Potency estimates of preparations relative to the standard preparation are available for both unweighted and weighted regression analyses together with detailed analysis of variance, estimates of slope and other relevant parameters. The general comparisons of dose-response relationships produced by the program are a feature of particular interest. However, an option which suppresses the more general output is available if the program is to be used for analysis of a 'screening' assay comparing single dilutions or doses of test samples with a standard curve. Data input is designed to permit immediate running of the program by junior personnel. Data output is designed to facilitate record keeping.

Biological Assay↗