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At least 1,117 records · Page 62Linked to original sources
PubMed1977

Reversible hematologic sequelae of diabetes mellitus.

Seven patients with diabetes mellitus were hospitalized and their blood sugar concentrations regulated as a result of fasting blood sugar, sugar around meals, urinary sugar, and hemoglobin AIC assays. Erythrocyte half-life as measured by 51 Cr increased in all patients from a mean of 27 days to 31 days, while hemoglobin AIC levels decreased from a mean of 10.1% to 5.6%. Leukocyte adherence increased in all patients from a mean of 28% to 51%. Most striking were the changes observed in platelet function in response to epinephrine. The length of the secondary lag phase of platelet aggregation, after a stimulus with final concentration of 70 muM of epinephrine, increased from a mean of 19 seconds to 65 seconds. Studies in additional patients confirmed an inverse correlation between hemoglobin AIC concentration and the secondary lag phase (r = 0.87, P less than 0.001). These studies found that certain secondary sequelas of diabetes can be corrected by strict carbohydrate control and confirmed that hemoglobin AIC assays provide a useful means of showing the degree of control of glucose metabolism in diabetic patients.

Adolescent↗
PubMed1979

The chronic sequelae of non-A, non-B hepatitis.

Twenty-six of 388 patients (6.7%) followed prospectively after open-heart surgery developed non-A, non-B hepatitis. Of these 26, 12 had an elevated (often fluctuating) serum alanine aminotransferase (SGPT) for greater than 1 year. Liver biopsy, done in eight of 12, showed chronic active hepatitis in six and chronic persistent hepatitis in two; one patient with chronic active hepatitis had early cirrhosis. Anicteric patients with peak SGPT greater then 300 IU/L were at greatest risk of developing chronic hepatitis. Chronic non-A, non-B hepatitis was symptomatically mild and unaccompanied by physical signs or laboratory evidence of autoimmune disease or severe chronic liver disease. In all 12 patients there was spontaneous improvement in serum transaminase over a period of 1 to 3 years, and four patients had sustained normalization of SGPT. Thus chronic active hepatitis is a common sequela of acute non-A, non-B hepatitis but may have a better prognosis than chronic active hepatitis of other causes.

Acute Disease↗
PubMed1996

Ischemic cerebellar infarct in a 5-year-old boy: sequela to minor back trauma.

Minor trauma, a kick to the center of the back during roughhousing with an 8-year-old sibling, produced an ischemic cerebellar infarct in a 5-year-old boy. The boy was brought to medical attention because of vomiting and headache. He also had ataxia. Results of laboratory studies, structural examination, and cerebrospinal fluid analysis were noncontributory. An irregular, low-density region in the left cerebellar hemisphere of unknown cause was seen on computed tomography scans. Magnetic resonance imaging (MRI) revealed an area of signal alteration hyperintense on the T2-weighted image and mildly hyperintense on the proton-density image in the leftward cerebellar hemisphere. The distribution was most compatible with that of an acute superior cerebellar arterial infarction. No other abnormalities were detected. The patient was treated with oral prednisolone, recovered, and had no further episodes or sequelae. The authors recommend that post-traumatic stroke be considered early in the differential diagnosis of a child with the triad of symptoms seen in the patient described. They suggest that glucocorticoid therapy on a short-term basis may have a place in more rapid resolution of symptoms.

Anti-Inflammatory Agents↗
PubMed1999

[Tuberculosis sequelae in Japan].

Tuberculosis had been the leading cause of death in Japan until 1950, and in these days there were about 3 million patients with active tuberculosis every year. From about 1950 to 1960 surgery was the treatment of choice if there were cavities and the lesions were regional. The number of patients who had thoracoplasties and/or pulmonary resections at national sanatoriums during the period of 1954 to 1961 was about 200,000. Since national sanatoriums had about 25% of the total beds for tuberculosis in Japan at that time, the total number of surgically treated patients would be around four times this number, that is 0.8 to 1.0 million. Many of those who survived suffered later from complications, which included chronic respiratory failures, chronic hepatitis (hepatitis C), liver cirrhosis and/or hepatic cell carcinomas. There are at least 50,000 patients who are under home oxygen therapy (HOT) in Japan, of whom about 30% are those with pulmonary tuberculosis sequelae (TBS). The survival rate after the start of HOT in these patients was found better in those who had surgical treatments than in those who had medical treatments only. Since hypercapnea was more common in the former, better survival rates in the hypercapnic than in the normocapnic patients with TBS as a whole could be due to the fact that more of the surgically treated patients were included in the hypercapnic group. For this reason, it is premature to conclude that hypercapnea is an independent favorable prognostic factor in TBS patients with chronic respiratory failure. Because more than one-forth of thoracoplasties and/or pulmonary resections were done in national sanatoriums, it is the responsibility of those who are now working in national hospitals to treat and support these patients with TBS who developed complications such as respiratory failures, chronic hepatitis, liver cirrhosis, and/or hepatic cell carcinomas.

Chronic Disease↗
PubMed1999

[Home mechanical ventilation as a treatment of the sequelae of tuberculosis surgery].

Nasal intermittent positive-pressure ventilation (NIPPV) has been showed useful for the treatment of chronic respiratory failure in patients with chest wall diseases due to sequelae of tuberculosis. We present a report of a patient with a thoracoplasty and a cavernostomy in situation of chronic respiratory failure. Nasal intermittent positive pressure ventilation improved diurnal hypoxaemia and hypercapnia.

Aged↗
PubMed1976

[Progressive course of the sequelae of closed cranio-cerebral trauma at remote periods (in relation to the test of rehabilitating invalids from the Second World War)].

On the basis of modern knowledge of the clinical picture, pathophysiology and pathomorphology of the residual period of brain injuries and a study of 140 cases, examined in the Central Institute for Expertise of Working Capacity the author discusses some clinical characteristic of the remote sequelae of brain injuries received during the war and the possible variants of their pathogenesis. A comprehensive clinical study of such patients with the use of paraclinical methods (EEG, REG) permitted to establish a cerebro-vascular nature of these disorders with a development of vasopathy, traumatical hypertension, early vascular involution with a transition to early cerebral atherosclerosis. Having this in view the author considers some problems of the causal connections of these disorders with injuries and concussions received at war.

Adolescent↗
PubMed1999

[Burn sequelae in developing countries].

Based on their experience in the reconstruction of burn sequelae acquired over the last decade in India and Africa, the authors try to define a number of elements applicable to every case and in every country: the importance of preparation of missions in the foreign country and in France, concerning material and all team personnel; the particular conditions of anaesthesia-intensive care; surgical criteria of efficacy, rapidity, simplicity and reproducibility. Full-thickness skin grafts and reliable local or regional flaps are the preferred techniques. The authors consider that there is no place for expansion prostheses and microsurgical free flaps in this setting.

Adult↗
PubMed1999

[Controversy regarding the sequelae of minor craniocervical trauma with special reference to neurobiological aspects of cognitive disorders].

This paper focuses primarily on the biomechanical factors which may lead to a substantial brain-tissue lesion following cranio-cervical trauma. Emphasis is placed on pathoanatomical findings and clinical parameters in the assessment of trauma-severity. Results from previous research are highlighted to demonstrate close interrelationship between the severity of a trauma and neurological, psychological, neuropsychological sequelae or lesions visible by neuroimaging. Knowledge of this interrelationship clearly indicates the necessity of proper initial assessment to allow reliable prognosis of outcome and establishment of treatment strategies.

Biomechanical Phenomena↗
PubMed1998

[Neurologic sequelae in severe carbon monoxide poisoning--case report].

The symptoms and clinical course of severe acute poisoning with carbon monoxide in 22-years-old man is described. To evaluate neurological sequelae, magnetic resonance imaging (MRI) repeatedly was performed. In initial examination, at week 7 after intoxication, MRI showed bilateral abnormalities of the amygdaloid nucleus, caudate nucleus and in globus pallidus at right. Haemorrhagic lesion of internal capsule was shown 10 days later. In the next examinations regression in basal ganglia was observed, but slight atrophy of brain was stated. Neuropsychological examinations performed simultaneously, allowed to evaluate the dynamics of central nervous system disfunction.

Adult↗
PubMed1999

[Central apnea with consciousness impairment due to Listeria rhombencephalitis sequelae].

Listeria neuromeningitis presents as febrile rhombencephalitis in half the patients, often with persistent sequelae such as cranial nerve palsy. We report the case of a man who developed central apnea with simultaneous consciousness impairment subsequent to an infectious disease. Magnetic resonance imaging showed low signal intensities in T1 and T2, particularly in the medulla. Neither acidosis, hypoxia nor hypercapnea stimulated the respiratory centers during episodes of apnea; ventilation started again only with strong voluntary stimulation. Pons and medulla lesions of the reticular formation were probable as well as lesions of the automatic respiratory system and could explain the central origin of the apnea in this patient.

Cerebral Palsy↗
PubMed1998

[Complications and sequelae of the purulent, bacterial meningoencephalitis in the material from the 1st Clinic of Infectious Diseases of Silesian Medical Academy in Bytom in the years 1991-1997].

From 1991 to 1997 at the I Clinic of Infectious Diseases of Silesian Medical Academy in Bytom 123 patients with purulent, bacterial meningoencephalitis were treated. Mortality in the analysed group was 28.5% (35 cases). In the course of disease various complications were observed: seizures (43.1% cases), ischaemic stroke (2.4% cases), brain abscess (4.1%). Permanent consequences subsequent to the disease were found in 16.3% cases: deafness and partial deafness, psychic disorders, paresis and paralysis, epilepsy and cranial nerves paralysis. Bacterial infections of the central nervous system are still danger diseases producing high lethality, complications and subsequent neurological sequelae.

Abscess↗
PubMed1999

[Prospective 12-year follow-up study of clinical and hemodynamic sequelae of deep venous thromboses in patients with low risk (Zurich Study)].

No prospective study of the long-term sequelae of more than 10 years after acute deep vein thrombosis exists so far. Therefore, 28 patients with DVT were included in a prospective study to evaluate the natural history of postthrombotic syndrome. Clinical and hemodynamic examinations were performed at the time of admission; after 3, 6 and 12 months; after the 2nd, 3rd, 4th, 5th; and finally after the 12th year. All patients received unfractionated heparin initially and oral anticoagulants subsequently. After 12 years, 64% of the patients exhibited normal findings. Mild skin changes were found in 28%, marked trophic changes in 5%, and only 1 venous ulcer occurred. Regular use of compression stockings was reported by 54% of the patients with multilevel disease. Although mean maximum venous outflow was significantly reduced from the acute event to 2 years later (p < 0.003) compared with the contralateral leg, a significant (p < 0.05) improvement was observed 6 months later. Recanalization of calf vein thrombosis was detected by Doppler sonography after 3 months. 64% of the multilevel thromboses were recanalized completely or in part after 1 year; in 69%, valvular incompetence was found. In conclusion, in contrast to earlier reports, this prospective study up to 12 years after DVT demonstrates a low incidence of PTS by administration of initially unfractionated heparin, oral anticoagulation and compression therapy. However, the adverse clinical event rate (mortality 14%) and recurrency rate of 24% show that the prognosis after DVT does not appear favorable even in low-risk patients.

Adult↗
PubMed1999

Health sequelae of breastfeeding for the mother.

Breastfeeding is known to demand use of maternal nutrient stores, but few comment on the positive health benefits of breastfeeding for the mother. Breastfeeding reduces the risk of postpartum blood loss by increasing the rate of uterine contraction, lowers the risk of postpartum blood loss by increasing the rate of uttering contraction, lowers the risk of postpartum blood loss by increasing the rate of uterine contraction, lowers the risk of premenopausal breast cancer and also reduces the risk of ovarian cancer, reduces lifetime menstrual blood loss, may reduce rate or severity of infections, may reduce the risk of spinal and hip fracture after menopause, and may support bonding with the infant as well as an improved sense of self-esteem and success with mothering. This article reviews the literature on short- and long-term sequelae of breastfeeding for women.

Breast Feeding↗
PubMedDate not supplied

Sequelae and prognosis of intruded primary incisors: a retrospective study.

PURPOSE: This study was designed to assess the sequelae and prognosis of intruded primary incisors. METHODS: Of 196 children who visited the emergency clinic due to intrusion of 310 maxillary primary incisors, 110 children (172 teeth) were available for follow-up examination (study group). Eighty-six children (138 teeth) did not show for the follow-up examination (non-respondents group). Male/female ratio was 1.7:1. Age range of children at time of injury was 12-72 months (mean 28). Follow-up time ranged between 0 and 59 months (mean 27). RESULTS: Fifty-seven percent of all teeth were completely intruded. In 80%, the root was pushed labially. All but two ankylosed teeth re-erupted, and 37% of these re-erupted into an ectopic position. Completely intruded incisors re-erupted into an ectopic position in a higher percentage (45%) than partially intruded teeth (30%). Fifty-two percent of the teeth presented pulp canal obliteration (PCO). Sixty-four percent of the completely intruded incisors presented PCO compared to 40% of partially intruded teeth. Arrest of dentin apposition was found in 15% of the teeth, and was not affected by the degree of intrusion. Twenty-three teeth were extracted shortly after the injury due to suspect of contact with the developing permanent successor (19 teeth) and severe caries (4 teeth). Sixty-eight percent of the intruded teeth survived more than 36 months after the injury. Twenty-three percent were extracted due to periodontal breakdown and 5% due to repeated trauma. Antibiotic therapy did not have any effect on the survival rate. CONCLUSION: The majority of intruded primary incisors may re-erupt and survive with no complications after more than 36 months post trauma even in cases of complete intrusion and fracture of the labial bone plate.

Age Distribution↗
PubMedDate not supplied

[Amputation of the lower extremities in angiopathies and reamputation as a sequelae of postoperative complications].

In the period from January 1985 till January 1995 in the Clinic of Traumatology and Orthopedics of Military Medical Academy were treated 305 patients with 317 primary amputations of the lower extremities that were performed as the sequelae of ischemia and necrosis on the basis of occlusive changes, arteriosclerosis and diabetes. Out of the total number of operated patients, 210 were with diabetes mellitus. The amputations were performed at the level of: foot in 102 (32.17%), lower leg in 145 (45.74%) and upper leg in 70 patients (22.09%). Reamputations were performed in 52 patients (16.4%): at the level of foot in 22 (6.94%), lower leg in 17 (5.36%) and upper leg in 13 patients (4.10%). Tourniquet was used during the surgery of primary amputation in 56 patients.

Adult↗
PubMed1999

[Surgical methods in the treatment of patients with sequelae of hip joint injuries].

The article analyzes results of treatment of 64 patients with sequelae of traumas of the hip joint. They showed that arthrodesis of the hip joint was indicated in treatment of young patients with severe posttraumatic coxarthrosis, destruction of the cotyloid cavity or the femur head including those after fighting injuries of the joint, purulent complications after traumas or preceding operations. Intertrochanteric osteotomy of the femur is reasonable in treatment of young patients with the initial stages of coxarthrosis and preserved amplitude of movement of the joint. Endoprosthesis of the hip joint is the operation of choice in patients older than 40-45 years with posttraumatic coxarthrosis and aseptic necrosis of the femur head, as well as in patients with the recurrent pain syndrome after intertrochanteric osteotomy.

Adolescent↗