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Results for “Musculoskeletal Development”

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At least 1,117 records · Page 62Linked to original sources
PubMed1999

Quantitative MR measures of three-dimensional patellar kinematics as a research and diagnostic tool.

PURPOSE: A three-dimensional (3D) study of normal patellar-femoral-tibial (knee) joint kinematics was performed using Cine Phase Contrast Magnetic resonance imaging (Cine-PC MRI) to determine the utility of this technique as a diagnostic tool in defining alterations in patellar tracking. METHODS: Cine-PC MRI was originally developed to measure heart motion and blood flow and has now been adapted to the study of the musculoskeletal system. Thus, for the first time knee joint kinematics can be studied three-dimensionally, noninvasively, and in vivo during dynamic volitional leg extensions under load. Cine-PC MRI provides one anatomic and three orthogonal velocity images (vx, vy, and vz) for each time frame within the motion cycle. Bone displacements are calculated using integration and are then converted into both 3D orientation angles and 2D clinical angles. RESULTS: The 3D patellar tilt and 2D clinical patellar tilt angle were nearly identical, even though these two angles have distinct mathematical definitions. The precision of the 2D clinical patellar tilt angle (N = 3) was approximately 2.4 degrees. CONCLUSIONS: Since the overall subject (N = 18) variability for clinical patellar tilt angle and medial/lateral patellar displacement was low (SD = 2.9 degrees and 3.3 mm, respectively), Cine-PC MRI could prove to be a valuable tool in studying subtle changes in patellar tracking.

Adult↗
PubMed2001

Sensitization, subjective health complaints, and sustained arousal.

The purpose of this presentation is to discuss the possibility that sensitization is a psychobiological mechanism underlying not only multiple chemical sensitivity (MCS), but a much more general cluster of illness, referred to as "subjective health complaints". Sustained arousal, or sustained "stress" responses, may be an important factor for the development of these conditions. Patients with subjective complaints without objective changes are sometimes referred to as having "fashionable diagnoses" or "unexplained symptoms". They may be given diagnoses like MCS, epidemic fatigue, chronic fatigue syndrome, burnout, stress, a variety of intoxications, environmental illness, radiation, multiple chemical hypersensitivity, food intolerance, functional dyspepsia, irritable bowel, myalgic encephalitis, postviral syndrome, yuppie flu, fibromyalgia, or vital exhaustion. One issue is whether this is one general condition or separate entities. Another issue is whether sensitization may be the psychobiological mechanism for most or all of these conditions. Finally, is it likely that sustained arousal may facilitate the development of sensitization in some or many neural circuits? In this review, the main emphasis will be on musculoskeletal pain. This is the most frequent and most expensive condition for sickness compensation and disability. The comorbidity of other complaints, however, will also be taken into account.

Adaptation, Physiological↗
PubMed1984

A family with multiple musculoskeletal abnormalities.

A family with multiple musculoskeletal abnormalities is reported. The disorder is characterised by platyspondyly, abnormality of the upper femoral epiphyses, and the development of precocious osteoarthritis. It is proposed that this family represents an example of autosomal dominantly inherited spondyloepiphyseal dysplasia tarda (SED tarda).

Adolescent↗
PubMed1994

Acute effects of hindlimb unweighting on satellite cells of growing skeletal muscle.

The proliferative behavior of satellite cells in growing rat soleus and extensor digitorum longus muscles was examined at short periods after initiation of hindlimb unweighting. Mitotic activity of satellite cells in both muscles decreased below weight-bearing control levels within 24 h of initiation of hindlimb unweighting. This satellite cell response was > or = 48 h before any atrophic morphological changes that take place in the muscles. Suppression of mitotic activity was most severe in the soleus muscle where continuous infusion of label demonstrated that virtually all mitotic activity was abolished between 3 and 5 days. The results of this study suggest that satellite cell mitotic activity is a sensitive indicator of primary atrophic changes occurring in growing myofibers and may be a predictor of future morphological changes.

Animals↗
PubMed2004

Valgus and varus deformity after wide-local excision, brachytherapy and external beam irradiation in two children with lower extremity synovial cell sarcoma: case report.

BACKGROUND: Limb-salvage is a primary objective in the management of extremity soft-tissue sarcoma in adults and children. Wide-local excision combined with radiation therapy is effective in achieving local tumor control with acceptable morbidity and good functional outcomes for most patients. CASE PRESENTATION: Two cases of deformity after wide-local excision, brachytherapy and external beam irradiation for lower-extremity synovial cell sarcoma are presented and discussed to highlight contributing factors, time course of radiation effects and orthopedic management. In an effort to spare normal tissues from the long-term effects of radiation therapy, more focal irradiation techniques have been applied to patients with musculoskeletal tumors including brachytherapy and conformal radiation therapy. As illustrated in this report, the use of these techniques results in the asymmetric irradiation of growth plates and contributes to the development of valgus or varus deformity and leg-length discrepancies. CONCLUSIONS: Despite good functional outcomes, progressive deformity in both patients required epiphysiodesis more than 3 years after initial management. There is a dearth of information related to the effects of radiation therapy on the musculoskeletal system in children. Because limb-sparing approaches are to be highlighted in the next generation of cooperative group protocols for children with musculoskeletal tumors, documentation of the effects of surgery and radiation therapy will lead to improved decision making in the selection of the best treatment approach and in the follow-up of these patients.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed2004

[Work ability among nursing workers at the emergency service of a university hospital].

In a couple of years, the demographic and epidemiologic transition observed in Brazil will put this country in a worldwide position of prominence in relation to the aged population. Furthermore, the need for economic adaptation and consequent changes in Brazilian social security will result in workers staying in the labor market for a larger period of time, thus influencing their functional ability. This study aimed to evaluate work ability among nursing workers at the Emergency Service of a University Hospital. Study participants were fifty-four workers (40 women and 14 men), whose ages ranged from 23 to 53 years (average age 37.3 years). We used the Work Ability Index (WAI), an instrument developed in Finland, which presented an average value of 42.0. The most mentioned diseases with medical diagnosis were musculoskeletal, cardiovascular, respiratory and neurological. We consider that health promotion at work is one of the fundamental aspects for maintaining work ability.

Adult↗
PubMed1992

Leg length inequality. Implications for running injury prevention.

Leg length inequality is a relatively common musculoskeletal malalignment related to structural, postural and environmental factors. The inequality is a plausible aetiological factor in the development of a variety of overuse injuries because it alters the magnitude and distribution of mechanical stress within the body. Leg length inequality has been linked with lower extremity stress fractures, low back pain, hip pain and vertebral disk problems of runners. The appropriateness of using inshoe lifts to reduce or eliminate the inequality has not been rigorously evaluated. Further research is needed to quantify the biomechanical effects of leg length inequality as it interacts with other factors related to running injury.

Athletic Injuries↗
PubMedDate not supplied

Dynamic duo.

Working in the community as manual handling nurse specialists, Linda Rankin and Emily Millar have run education programmes for parents and carers of mobility-impaired children as well as staff. Last week they were named Northern Ireland nurses of the year.

Awards and Prizes↗
PubMed1984

Muscularity as a function of species, sex and age in small mammals.

The size of individual skeletal muscles in mammals is well known to change with the degree of mechanical loading imposed on the muscle. Less clear has been the effect of changes in loading of the whole organism on size of the total skeletal musculature. Pitts and coworkers have provided valuable insights by dissection and weighing of the skeletal musculature of animals subjected to various chronic centrifugation, exercise and dietary regimens, and their recent findings are reported at this meeting. However, questions remain. Independently, our laboratory several years ago embarked on a systematic definition of body composition and energy metabolism changes as a function of sex and age in 5 species of small laboratory mammals, the mouse, hamster, rat, guinea pig and rabbit. Six animals of each sex were examined in 8 age cohorts ranging from 1 to 24 months for each of the 5 species.

Aging↗
PubMed2004

[Noise-induced hearing loss--factors affecting worker's decision to submit a disability claim].

Noise-induced hearing loss is recognized worldwide as a prevalent work-related morbidity and is the most common compensated occupational disease in Israel. Despite extended legislation, hearing conservation programs, surveillance and biological monitoring (by audiometry) of work sites and workers, the burden of this injury remains high. As a rule, afflicted workers refrain from filing compensation claims and do so only at later stages when both subjective and objective evidence of advanced hearing loss is present. We have evaluated the determinants that seem to influence the decision of an individual worker to file a claim. We found that the major determinants are subjective perception of the level of hearing disability and clinical symptoms such as: tinnitus (OR = 3.3 with CI 95% = 2.1 5.2), verbal communication disturbances (OR = 2.7, 95% CI = 1.9-3.8), complaints of dizziness (OR = 1.9, 95% CI = 1.4-2.5), severity of hearing impairment (by audiometry with OR = 1.04, 955 CI = 1.02-1.06) and musculoskeletal complaints (OR = 1.6, 95% CI = 1.2-2.2). These findings attest to the relatively late stage in the development of noise-induced hearing loss at which workers file a claim for compensation and rehabilitation. In order to alleviate the burden of this injury in the future and encourage workers to approach the National Insurance Institute at an earlier stage, we suggest several ways of intervention and improving the awareness of all parties concerned.

Audiometry↗