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Results for “Forelimb”

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At least 1,117 records · Page 62Linked to original sources
PubMed1984

Regeneration of surgically created mixed-handed axolotl forelimbs: pattern formation in the dorsal-ventral axis.

The regeneration of surgically created mixed-handed limb stumps is examined in the axolotl. Operations were performed in the lower arm and upper arm regions and grafts were allowed to heal for approximately one month prior to amputation or were amputated immediately. In the lower arm group both anterior and posterior limb halves were inverted, whereas only posterior halves were inverted in the upper arm group. Almost all the limbs regenerated were normal in the anterior-posterior axis, whereas a range of limb types were found when the dorsal-ventral axis was analysed using the metacarpal muscle pattern and epidermal Leydig cell number as positional markers. The carpal and forearm muscle patterns were also analysed in order to assess whether the pattern determined from analysis at the metacarpal level reflected that seen at more proximal levels. The results are discussed in terms of the possible role of cell contribution from the stump to the blastema and the relevance of the study to models of pattern regulation.

Ambystoma↗
PubMed1983

[Activity of afferent neurons after thermal stimulation of the skin of the cat forelimb].

The activity of 97 fibers of dorsal roots of lower cervical and upper thoracic segments of the spinal cord was studied in adult cats. The conduction velocity of afferents from skin receptors in respect to mechanical and temperature sensitivity was measured. All temperature-sensitive units appeared to be mechano-sensitive as well. The level of spontaneous activity and the conduction velocity of the units were defined by temperature sensitivity. The reaction parameters seem to depend on morphological properties of the skin receptors.

Animals↗
PubMed1983

[Localization of temperature-sensitive and non-temperature-sensitive cutaneous receptors in the forelimb of the cat].

87 afferent fibres in dorsal roots of lower cervical and upper thoracal segments of the spinal cord and their responses to thermal and mechanical stimulation of skin receptors were studied in adult cats. Higher conduction velocities and larger fibre diameters were found for receptors located more distally in the forepaw skin. The location of the receptive fields of thermosensitive and nonthermosensitive units is different.

Animals↗
PubMed1980

Increased activities of acid protease and acid phosphatase in denervated forelimb regenerates of the adult newt, Notophthalmus viridescens.

Early bud and palette limb regenerates of the adult newt, Notophthalmus viridescens, were compared with respect to the effect of denervation on the activities of some of their hydrolases in order to determine if these enzymes contribute to the atrophy of denervated regenerates. Results show that denervation increased total activities of acid protease and acid phosphatase by 77-89% and 41-45% respectively at both stages examined. Both membrane-bound and soluble enzymatic forms contributed to the observed increase in the total activity of each hydrolase. Furthermore, the actual levels of each enzyme attained at the two stages following denervation were quite similar to each other. Since each hydrolase responded to denervation in a similar way at both stages examined, it was concluded that resorption of denervated limb regenerates is not primarily due to the increased activity of hydrolases. Denervated early bud regenerates, which are almost completely resorbed following nerve withdrawal, would be expected to show greater levels of hydrolytic activity than denervated palette regenerates, which exhibit only a partial resorption following the same operation.

Acid Phosphatase↗