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At least 1,117 records · Page 62Linked to original sources
PubMedDate not supplied

[The so-called angiodysplasias of the digestive system].

The chapter on angiodysplasias of the gastrointestinal tract raises numerous, still problematic, issues: classification of the disorder (its clinical presentation and classification) its anatomo-pathological identification diagnosis of its nature and localization treatment of patients with acute massive bleeding long-term outcomes The possibility that an angiodysplasia underlies a bleeding event, even serious, makes this a timely topic. The exiguity of the lesion responsible for bleeding entails noteworthy diagnostic difficulties. By contrast, the relative rarity of such events, as well as of pertinent evidence in literature, do not allow a better understanding of the disease or, above all, its management. Nevertheless, it is important to bear the disorder in mind when faced with massive bleeding of unknown origin.

Angiodysplasia↗
PubMedDate not supplied

[13 cases of angiodysplasia of the digestive system].

OBJECTIVE: This clinical study assesses the diagnostic and therapeutic problems entailed in so-called gastrointestinal angiodysplasias. Summary back ground data: the topic presents numerous, still unresolved, issues: classification (its clinical presentation and classification); anatomo-pathological identification; diagnosis and localization; treatment of patients with acute massive bleeding; long-term outcomes. MATERIALS AND METHODS: Thirteen patients, equally distributed between both sexes an with a mean age of 54 years (range = 23-75), were observed and operated over a nearly 20 year period. All patients had acute massive bleeding localized to the stomach, duodenum, ileum, colon and rectum. Diagnosis and localization were previously obtained in nine patients, mostly using selective angiography. With the exception of two rectal localizations treated with embolization, all patients underwent surgical resection. In two cases operated on without previous diagnosis, (rebleeding occurred). CONCLUSION: The data available in the literature are broadly substantiated, even if the mean age reported seems somewhat lower (54 yrs). Localizations were detected in nearly all segments of the gastrointestinal tract, and the indication to surgical resection possibly after detection of the angiodysplasia and source of bleeding is confirmed. The best diagnostic technique is selective angiography.

Adult↗
PubMed2002

[Value of interventional video-endoscopy in the assessment of cancer of the upper airways and digestive system].

INTRODUCTION: The aim of our study was to evaluate the video fiberoscope with operator canal (FOC) in he diagnosis of head and neck carcinoma compared to direct laryngoscopy (DL). METHODOLOGY: From August 2000 to May 2001, 82 patients were included in a prospective study. They were examined for pharyngolaryngeal cancer with the FOC, DL and a CAT-SCAN. The compared elements were the visualization of the different regions of the pharyngolarynx. A three dimensional description of the lesion, the presence of secondary localisations as well as the anatomo pathological results were obtained with FOC and DL. RESULTS: Although the pharyngolarynx is less well visualized in FOC than in DL (p = 0.04), no statistically significant difference was found between the two methods in terms of visual diagnosis and assessment of the extent of the lesion. The sensitivity of the biopsies made with FOC is lower than those performed with DL (66% FOC, 97% DL). Moreover, we have noted that FOC is highly reliant on the experience and ability of the surgeon. CONCLUSION: DL remains the most reliable technique for the exploration and diagnosis of the pharyngolarynx. If it is not possible to perform a DL or if it is not indicated (trismus, contra-indication to general anaesthesia) FOC should be considered as the examination of choice.

Adolescent↗
PubMedDate not supplied

[Treatment of aggressive primary lymphomas of the digestive system by intensive chemotherapy. Experience of the Study Group on Lymphomas in Adults with the LNH-84 protocol].

Ninety-one patients with primary gastrointestinal lymphoma included in the LNH-84 multicentric regimen were analyzed to determine the efficacy and the toxicity of intensive combination chemotherapy and of surgical debulking. All these patients had aggressive histological subtypes: 56 patients had localize disease, stage IE or IIE, and 35 patients had stage IV disease; 40 patients had bulky disease. Specific sites included stomach (43 cases), small bowel (35), ileo-cecum (13), colon (10), and rectum (6). Although 71 patients (78%) had an attempted surgical resection, only 28 (31%) had complete tumor excision. Patients were treated with 3 or 4 cycles of ACVB chemotherapy followed by sequential consolidation. Nine patients died during chemotherapy. With a median follow-up of 3 years, 10 patients have relapsed and predicted 4-year survival of the entire group is 62%. In stage IE or IIE patients, survival and disease-free survival are similar in patients who underwent complete resection or incomplete or no surgical resection prior to the administration of chemotherapy. Prognostic factors predicting for survival were similar to the entire group of patients treated with the LNH-84 regimen. Aggressive gastrointestinal lymphoma patients treated with intensive chemotherapy have outcome and prognostic factors comparable to those of other similarly staged aggressive lymphoma patients. Surgical resection prior to the administration of combination chemotherapy did not influence survival or disease-free survival in patients with localized disease.

Adolescent↗
PubMedDate not supplied

[The Mediterranean diet and occurrence of malignant tumors of the digestive system in the Croatian islands].

The aim of this study was to compare the age-standardised incidence rates of gastric bowel and pancreatic cancer between two regions of the Republic of Croatia: (1) five middle Dalmatian islands (Brac, Hvar, Korcula, Vis and Lastovo) with "Mediterranean" nutrition; (2) the control population of Koprivnicko-krizevacka County (KKC) with "continental" nutrition. The characterisation of nutrition habits in the two study regions revealed very significant differences. The newly registered cases of gastric, bowel and pancreatic cancer between 1986 and 1995 were retrieved from the Cancer Registry of Croatia. The resulting incidence rates were standardised to the standard world population using the method of direct standardisation. Age-standardised incidence rates in the islands in comparison to the control KKC population per 100,000 inhabitants were 17.2 vs. 39.4 (p < 0.001) in males with gastric cancer, 9.1 vs. 16.5 (p < 0.01) in females with gastric cancer, 34.5 vs. 31.4 (p > 0.05) in males with bowel cancer, 18.3 vs. 20.3 (p > 0.05) in females with bowel cancer, 5.5 vs. 9.0 (p < 0.05) in males with pancreatic cancer and 2.7 vs. 5.0 in females with pancreatic cancer (p < 0.05). Standardised incidence rates of gastric and pancreatic cancer in the island populations were significantly lower from the standardized Croatian average. The study showed that "Mediterranean" type of diet could have a protective effect against gastric and pancreatic cancer.

Croatia↗
PubMed1992

[Occurrence of Clostridium difficile in the digestive system of dogs].

This study was aimed at seeking strains of Clostridium difficile in feces and investigation of influence of antibiotics application on frequency of isolation and detection of toxing in vivo produced by this microorganism. Samples of feces were obtained from experimental dogs consisting of two groups. To groups I belonged 150 healthy dogs. Group II consisted of samples of feces received from four dogs before and after application of various antibiotics. Clostridium difficile was not isolated from group I dogs. From dogs belonging to group II, 28 strains were isolated. Production of toxing and classification to serological groups of the isolated strains were performed. Presence of this microorganism in feces of dogs is evident only after multiple application of antibiotics. Results of these studies suggest that dogs may constitute a reservoir of Clostridium difficile.

Animals↗
PubMedDate not supplied

[The somatostatin analog SMA (201-995) as adjuvant treatment in patients with external fistulae of the digestive system].

Six patients with gastrointestinal fistulae treated with a potent inhibitor of gastrointestinal hormones, the somatostatin analogue SMS 201-995 are reported. All patients had severe intraabdominal diseases and underwent a mean of 3.5 surgery procedures during their hospital stay. When the patients were analyzed individually a mean reduction of 42.5% (P < 0.050 of basal fistulae output was observed after treatment. In three patients the fistulae closed after seven and ten days of treatment with the analogue; the other three patients died after a protracted hospital stay which included multiple admissions to the Intensive Care Unit. When the output of all fistulae treated where analyzed together it showed a tendency to decrease, but it didn't reach statistical significance.

Adult↗