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Results for “YUGOSLAVIA”

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At least 1,099 records · Page 61Linked to original sources
PubMed1993

Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia.

Human colorectal carcinoma tissue sampled from 37 patients, routinely graded into Dukes' stages A, B and C and histologically examined for the level of differentiation, were analyzed for the presence of point mutations in the K-ras oncogene. Seventeen cases out of the 37 analyzed were found to have a mutation in either the 12th or the 13th codon of the K-ras gene, giving an overall frequency of mutation of 46%. The incidence of mutations in Dukes' stages A, B and C was 33, 46 and 58% respectively. Although the frequency of mutation appears to be similar to that reported for the USA population, the spectrum of point mutations in codons 12 and 13 of the K-ras gene in the Yugoslav population appears to differ significantly. G-to-T transversions make up 77% of all mutations present, with the distribution as follows: 18% at the first base and 59% at the second base of codons 12 and 13. G-to-A transitions at the second base is the only other mutation identified, occurring mainly in codon 13 in colorectal tumors of all 3 stages.

Adult↗
PubMed1986

A randomized comparative trial of Nova-T and TCu200Ag in Yugoslavia.

The contraceptive efficacy and clinical performance of Nova-T and TCu200Ag were studied in a randomized comparative study with 819 interval acceptors. The 1- and 2-year gross termination rates were evaluated by means of the life-table method. The 12-month pregnancy rates were 1.0 per 100 women with Nova-T and 3.0 per 100 women with TCu200Ag. The preliminary 2-year rates were 1.7 and 5.5 per 100 respectively (p = 0.037). Rates of expulsion, medical and personal removals were not significantly different for the two devices. Continuation rates for the first year were 89.4 and 90.5 per 100 respectively.

Adult↗
PubMedDate not supplied

Medical relief personnel in complex emergencies: perceptions of effectiveness in the former Yugoslavia.

Humanitarian medical assistance and intervention during the civil war in Bosnia and Croatia was felt by national health workers to be relatively ineffective (2.8 on a 5-point Likert scale), compared to other forms of humanitarian assistance such as medical supplies (4.4/5) and non-medical materials (3.9/5). Bosnian physicians treating civilians noted that the most helpful types of personnel were surgeons and emergency physicians. This study suggests that assessment of personnel needs at the recipient level, in addition to standard relief assessments, is required early in models of complex emergencies. This study supports existing epidemiological models of complex emergencies, especially when high trauma-related mortality and morbidity are likely to occur.

Bosnia and Herzegovina↗
PubMed1980

Multicentre post-infarction trial of propranolol in 49 hospitals in the United Kingdom, Italy, and Yugoslavia.

A multicentre study of survivors of an anterior myocardial infarction is reported. The trial consisted of 720 patients and was a double-blind, placebo-controlled study with propranolol 40 mg three times a day. Trial entry was at two to 14 days (mean 8.5 days) and follow-up at one, three, and in most centres, six and nine months. The trial was designed to detect a 50 per cent reduction in mortality and this was not shown. The non-fatal reinfarction rate was similar in both groups. Subgroup analysis identified several prognostic risk factors for death, none of which interacted with treatment.

Clinical Trials as Topic↗