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Ehlers-Danlos syndrome (EDS) type IV: review of the literature.

Ehlers-Danlos syndrome (EDS) is a heterogeneous group of connective tissue heritable disorders. EDS type IV is a rare form that presents typical clinical signs, such as easy bruising and haematomas at sites of trauma, skin manifestations (translucent skin with visible veins), and joint hyperlaxity. To illustrate the dermatological features and describe an aggressive periodontitis, a symptom not yet reported in this EDS type, we present a case of a 23-year-old young man. This patient has been suffering from bruised skin, haematomas, and varicose veins in his legs. These lesions, typical of EDS type IV, were associated with trauma followed by slow and difficult cicatrization. Teeth loss and clinical attachment loss in all the remaining teeth, a symptom compatible with a severe destruction of the periodontal support, was reported after orthodontic treatment. The treatment is limited to control the disease and teeth loss. Considering this new clinical symptom associated with EDS type IV, we suggest that the use of orthodontic apparatus should be carefully considered in such patients.

Adult↗

Root lesions in a group of 50-60 year-old Germans related to clinical and social factors.

From a preventive point of view collection of data concerning carious and non-carious cervical tooth defects is definitely important. Consequently, the prevalence and distribution of different root lesions were studied and correlated with behavioral and biological factors in 50- to 60-year-old German individuals (n = 298). Additionally, the data were correlated with characteristics concerning oral health and known risk factors such as gender, educational level, and presence of plaque. An interview included questions on sociodemographic and socioeconomic characteristics, dental and general health status, and various behavioral parameters. During clinical examination data concerning coronal and root lesions, restorations, probing depth, gingival bleeding, and dental plaque were obtained. The participants represented a social middle class population with a high awareness of dental health. Obviously, for the participants, known risk factors for root decay such as gender, educational level and plaque index were of minor importance. Factors correlating with root caries were: (a) number of missing teeth, (b) probing depth, (c) smoking habit, (d) regular dental attendance and (e) the reason for the last dental treatment. Additionally, the prevalence of non cariogenic lesions, primarily resulting from increased but wrongly performed oral self care, seems gradually to relieve carious root destruction.

DMF Index↗

Periodontal disease and diabetes mellitus.

Infections of the tissue surrounding the teeth (periodontitis) are usually caused by anaerobic gram-negative microorganisms. This infection causes destruction of the supporting alveolar bone and can lead to tooth loss. Removal of these microorganisms can slow or arrest the progression of periodontitis. Diabetes patients are at greater risk of developing periodontitis, may not respond as well to periodontal therapy as nondiabetic patients, and may require more aggressive treatment to manage periodontitis. Microorganisms that cause periodontitis and the host response to these may increase insulin resistance in diabetic patients. Treatment of periodontitis could improve glycemic control. A model is presented in which periodontal pathogens may cause increases in proinflammatory cytokines that mediate increases in insulin resistance, resulting in an increase in blood glucose. Following periodontal therapy, this process may be reversed.

Diabetes Complications↗

Occlusal variation in a rural Kentucky community.

Some major theories concerning the etiology of malocclusion and its modern increase in frequency include genetic explanations, such as inbreeding, racial crossing, and accumulation of mutations, as well as such environmental causes as "habits," allergies, and caries causing reduced arch space of premature deciduous tooth loss. Reduction of masticatory stress resulting from modern urbanism is less often considered as an agent. Many examples of acquisition of gross malocclusion in aboriginal peoples immediately following dietary "modernization" contradict the genetic explanations. A rural population from central Kentucky presents several propitious social characteristics for epidemiologic study of occlusion. They have experienced almost no professional dental care, they are highly inbred (but less so during the last 30 years), and their diet included many difficult-to-chew foods until the recent introduction of industry to the area. Occlusion was evaluated according to the criteria of the Treatment Priority Index. The temporal change and correlates of occlusal variation were assessed on wax-bite impressions of thirty-four persons, informant dietary histories, and other information. The older inhabitants raised on more traditional diets show significantly better occlusion. Dietary consistency provides the most powerful explanation for the transition in occlusal variation, through it was not conclusive in these data.

Adolescent↗

Occlusal variation in Chinese immigrants to the United Kingdom and their offspring.

Occlusal variations of immigrant Chinese parents, raised in less developed areas, were compared with their children who were born and bred in the United Kingdom. Of 11 occlusal traits, nine were significantly more variable or less well developed in the offspring. Because genetic factors were unchanged, the deterioration in occlusion in the offspring indicates environmental influences such as dietary consistency, premature deciduous tooth loss from caries and oral respiration.

Adolescent↗

Prevalence and distribution of dental caries in a late medieval population in Finland.

The aim was to document the late medieval material and to compare the results with findings in other medieval populations and present-day Finns. The sample consisted of the remains of 410 individuals and included 4581 permanent and 600 deciduous teeth. Age determination was based on the stage of dental development and on the attrition pattern in the molar region. Scoring the presence and location of caries was done visually with the aid of a dental probe. In the younger age groups, caries was most prevalent in the occlusal fissures, but the proportion of cavities at these sites declined with age, possibly because occlusal attrition progressed more rapidly than did caries. In the permanent dentition, carious lesions were most frequently observed at the cementum-enamel junction, particularly on the approximal surfaces. The prevalence of caries was lower than among modern populations of similar ages. In addition, the relative distribution of caries was strikingly different, with root caries being the most common type.

Adolescent↗

The influences of fear, anxiety, and depression on the patient's adaptive responses to complete dentures. Part II.

The classification system of maladaptability presented in a previous paper was reviewed in the present one. Three major sources that significantly influence patient responses to tooth loss and subsequent dentures were discussed. They are parental influences, the symbolic significances of teeth, and current life circumstances. Each of the maladaptive categories is represented by these histories.

Adaptation, Psychological↗

Veterans Administration Cooperative Dental Implant Study--comparisons between fixed partial dentures supported by blade-vent implants and removable partial dentures. Part II: Comparisons of success rates and periodontal health between two treatment modalities.

Five Veterans Administration centers have participated in a study to determine whether fixed partial dentures (FPDs) supported by blade implants offer an acceptable substitute for mandibular unilateral or bilateral distal-base extension removable partial dentures (RPDs). The study design and methodology have been described in Part I. A total of 232 patients received comprehensive dental care including RPDs for 118 patients and FPDs for 114. Prespecified criteria determined treatment failures. During the 60-month period, treatment failures occurred in 19 FPD patients and 30 RPD patients. Ten FPD failures occurred before and nine after the FPD insertion. Five RPD failures were caused by abutment tooth loss and 25 for not using the RPD while eating. Life table analysis showed 5-year success rates of 84.2% for the FPD and 74% for the RPD. The 17.9% higher FPD success rate in Kennedy class II patients was both statistically and clinically significant. Excluding the 10 early failures, the 5-year FPD success rate was 91.5%. Of the 170 attempted implants, 26 failed, including 12 before the FPD fabrication. Radiographic assessments by a panel of three judges showed no bone deterioration during baseline to 60 months in 29.6%, slight in 25.4%, moderate in 15.9%, marked in 27%, and severe deterioration in 2.1% of the implant posts.

Blade Implantation↗

Predoctoral removable prosthodontics education.

As the 21st century is approached, changes are occurring that directly relate to removable prosthodontics at the undergraduate level. Edentulism will continue to decline, although the need for complete dentures will diminish slowly because of the replacement needs for the existing edentulous population. In the short- to medium-term future, partial edentulism will increase in the older population at the expense of total edentulism. Therefore, the need for removable partial dentures will increase, but subsequently will decline. In the long-term, tooth loss, regardless of etiology, will be reduced. However, the replacement of lost teeth is unlikely to disappear completely as a needed dental service. With 73% of dental schools reporting inadequate or marginal numbers of complete denture patients, Meskin and Entwistle have identified a shortage of patients needing removable prostheses. On the other hand, 50% of the schools report a surplus of removable partial denture patients. Dental school curriculum time related to prosthodontics has declined significantly over the past 20 years. However, over the past 10 years it has risen slightly. Techniques that are taught in dental schools are frequently not being used in practice. Yet the practitioner's interest in removable prosthodontics as it relates to new techniques and materials remains high according to a 1988 survey of Academy of General Dentistry members. Removable prosthodontics was rated first in regards to continuing education courses desired by its members. There are two basic objectives stated in the prologue of the Council on Dental Education Directive on Accreditation Standards. First, faculties are ultimately responsible for the quality of care rendered to the patient population by students.(ABSTRACT TRUNCATED AT 250 WORDS)

Curriculum↗

Comparison of mandibular bone in normal and osteoporotic women.

This study compared dental findings in normal and osteoporotic women and evaluated the variables that best separated the two groups. The osteoporotic group had less mandibular bone mass and density and a thinner cortex at the gonion than the normal group. The osteoporotic group also had a greater percentage of subjects who were edentulous. In subjects who had natural teeth, there was greater tooth loss. No differences in periodontal measurements were found between osteoporotic and normal groups. Mandibular bone mass and the number of teeth were statistically most effective for separating the populations. However, considerable overlap was found between the osteoporotic and normal groups in all variables.

Aged↗

A retrospective study of the effects of edentulism on the severity rating of tardive dyskinesia.

Edentulism has been reported to be a risk factor in the development of spontaneous orofacial dyskinesia. This study aimed to determine whether edentulism increases the severity rating of tardive dyskinesia in psychiatric subjects treated with neuroleptic medication. The filed Abnormal Involuntary Movement Scale reports of 84 edentulous and 109 dentate outpatients with schizophrenic or schizoaffective disorder were examined retrospectively. To compare dyskinesia ratings in different body areas with dental status and gender, 2 x 2 multivariate analysis of variance was used. Results show that edentulous subjects had significantly higher dyskinesia ratings in the orofacial categories but not in other body areas. Gender had no influence on dyskinesia ratings. These results indicate that tooth loss may considerably increase the severity of tardive dyskinesia, a finding that suggests a possible role of preventive and prosthetic dentistry in the health care of patients at risk for this condition.

Analysis of Variance↗

Periodontal care for community-dwelling older adults.

The prevalence and severity of periodontitis increases with age. Epidemiologic studies have identified several risk variables associated with advancing periodontitis in older adults: namely tobacco smoking, frequency of dental appointments, infection with anaerobic bacteria considered periodontal pathogens, plaque and calculus accumulation, and some socioeconomic variables. Future morbidity from periodontitis might be reduced by minimizing the impact of these risk-associated variables at younger ages. Treatment of periodontal disease in community-dwelling older adults should be aimed at (1) targeting care to their overall health, functional, and esthetic needs; (2) strategic planning for maximal health and patient satisfaction; (3) documentation of past susceptibility and current risk; (4) control of principal risk factors; (4) investing time in patient education and informed consent; and (5) planning ahead for a potentially catastrophic decline in health. Periodontal treatment needs should be met in an integrated treatment plan that considers the overall prognosis for the dentition and individual teeth and the most efficacious prosthodontic options. Frequent recall for supportive periodontal care is essential. Several medical, physical, and societal impediments to provision of optimal care for older adults should be sought and minimized by the practitioner. Population dynamics and health-oriented activism among older adults are increasing the demand for essential and elective periodontal and prosthodontic services, which are met by implant-supported prostheses. Over the next few decades, as the incidence of tooth loss declines and our knowledge of the pathogenesis of periodontitis and biology of tissue regeneration increases, there will likely be a renewed emphasis on the preservation of the natural periodontium.

Aged↗

Extensive idiopathic apical root resorption. A case report.

Multiple idiopathic external apical root resorption is an unusual phenomenon. A brief review of cases in the literature is presented as well as a report of a patient with severe resorption. No significant systemic, dental, or familial findings could be identified as a possible cause. Careful chronologic radiographic documentation showed that roots with normal length began to resorb several years earlier, and the resorption continued over a defined period of time, terminating spontaneously before tooth loss or obvious pulp damage. Because the pathogenesis is generally unknown, no specific treatment modalities exist at present.

Adult↗

Does gingivitis lead to periodontitis in young adults?

It has been assumed that poor oral hygiene predisposes to gingivitis with progression to periodontitis and tooth loss. However, a high prevalence of gingivitis occurs in some populations in which severe periodontitis is rare. To assess whether gingivitis is a reliable predictor of periodontitis, we compared the periodontal health of tea pickers and university students aged between 18 and 30 in Indonesia. Oral hygiene and gingival health was significantly better in students than in tea pickers. However, the prevalence and the severity of chronic periodontitis were similar in the two groups. Our findings suggest that gingivitis is a poor predictor of periodontitis in subjects younger than 30 years. Attempts to prevent periodontitis in young adults through antigingivitis measures such as plaque control may be unsuccessful.

Adolescent↗

Morbidity associated with incompletely erupted third molars in the line of mandibular fractures.

A retrospective analysis of 105 mandibular fractures associated with incompletely erupted third molars was undertaken. It was found that there was no difference in the rates of complication if the teeth were retained or extracted, or if an open or closed reduction was performed. The combination of tooth retention with open reduction, however, shows a trend toward being the treatment most prone to postoperative complications.

Fracture Fixation↗

Chronic adult periodontitis and burst progression may reflect local neutrophil defects due to perivascular hyaline deposits.

Chronic adult periodontitis (CAP) is a common disease of the supporting tissues of teeth, and is a major cause of tooth loss. This disease is distinguished from more rare rapidly progressing forms of periodontitis, in which a variety of neutrophilic polymorphonuclear leukocyte (PMN) defects have been identified. PMN dysfunctions have, however, not been observed in CAP. In CAP, destructive episodes of the disease occur sporadically and independently in different parts of the mouth. In this paper, it is proposed that CAP is due to highly localized defects in PMN function. Impaired PMN function is suggested as resulting in the formation of a virulent bacterial plaque, which is capable of initiating periodontal pocket formation. A previously reported perivascular hyaline material may account for localized PMN defects, by reducing the number of PMNs entering affected sites. The proposed model may explain both the presence of CAP in otherwise normal patients, and the sporadic pattern of tissue destruction seen in this disease.

Adult↗

Loading effects on rat craniomandibular morphology: a system for gravity studies.

Gravity effects on muscle and bone are a major impediment to long-term space travel. We introduce a model for studying these effects, the craniomandibular system. Some advantages of this system include: (1) craniomandibular morphology is determined by epigenetic factors including gravity, (2) relatively light forces can significantly alter its morphology, and (3) soft diet and tooth loss produce effects that are similar to those produced in lower limbs by weightlessness. In the study, implants made either of gold (experimental group) or lightweight acrylic (controls) were attached to adult rats' mandibles. After 13 weeks, the animals' skulls and mandibles were dissected. Pair-wise comparisons indicated that the experimental animals showed significantly shortened and narrowed cranial bases, and significant changes in the posterior zygomatic arch region. These results indicate that simulated macrogravity influences bone remodeling in the adult craniomandibular system.

Acrylic Resins↗

Influence of orthodontic derotation and extrusion on pulpal and periodontal condition of autotransplanted immature third molars.

The aim of this study was to determine the influence of orthodontic treatment on the pulpal and periodontal condition of 91 transplanted immature third molars. In patients with atrophy of the alveolar process or unfavorable root morphology, transplants had to be placed in extreme rotated or infraoccluded positions. After 3 to 6 months, these transplants were derotated (45 degrees to 90 degrees) to a correct position in the dental arch (derotation group; n = 28) or extruded to the occlusal plane (extrusion group; n = 21). Finally, approximal spaces were closed in both groups. A sample of 42 transplanted third molars with no orthodontic treatment need served as the control group. All transplants were followed clinically and radiologically for a mean period of 4.0 years. With respect to pulpal and periodontal conditions, no significant differences were observed between the control and the extrusion group. In contrast, compared with the control group, transplants in the derotation group had a significantly poorer pulpal and periodontal condition. In the derotated transplants, a significant correlation was detected between pulp necrosis and orthodontic treatment of multi-rooted transplants. This study indicates that orthodontic extrusion and minor lateral movements of autotransplanted immature third molars, as well as rotation of single-rooted third-molar transplants, represent no additional risk to transplant survival. In contrast, rotation of multi-rooted transplants seems to initiate later severance of the vascular and nerval supply to the pulp.

Adolescent↗