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[Liver transplantation in a case of angiosarcoma and thorotrast fibrosis (author's transl)].

After a short survey of the development of liver transplantation on the basis of three liver transplants performed in this department, a case of angiosarcoma due to thorotrast fibrosis is reported. The problems cocerning surgical technique have been overcome at this time. However the questions concerning immunology, procurement of organs and organ preservation are predominant. Critically observed, liver transplantation has not yet emerged from the stage of clinical experimentation today.

Hemangiosarcoma↗

[Thorotrastoma--late damage following thorotrast arteriography].

We report two cases of cervical thorotrastoma. Thorotrast is no longer used as a radiographic contrast agent, so that the rare thorotrastoma is often forgotten in the differential diagnosis of hypopharyngeal tumours. Surgical treatment of a thorotrastoma is not recommenced.

Aged↗

Thorotrastomas.

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Adult↗

[Focal nodular hyperplasia-like lesion of the liver associated with thorotrast liver disease--report of a case].

A 66-year-old man with Thorotrast liver disease underwent a partial hepatectomy for a small tumor of the liver, which was demonstrated by digital subtraction angiography. The resected specimen was grossly a sharply circumscribed, gray-yellow nodule, 7.5 mm in diameter. Microscopically, the nodule was an ill-defined hepatic cell mass, which was divided by fine fibrous septa irregularly and incompletely. Central veins and Glisson's capsules were not observed inside the nodule. Bile duct proliferation and infiltration of lymphocytes were found in the fibrous septa. There were Thorotrast depositions within the fibrous tissues around the nodule. Because a typical fibrous boundary and central scar were not found, we have termed this condition a focal nodular hyperplasia-like lesion. A relationship between focal nodular, hyperplasia as a precancerous state and Thorotrast liver disease was suggested.

Aged↗