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At least 1,099 records · Page 61Linked to original sources
PubMed2004

Activity-dependence of the "safe zone" for impingement versus dislocation avoidance.

Presently, the basis for optimal cup positioning to minimize the likelihood of dislocation rests upon subjective clinical impressions. To help elucidate optimal cup positioning more objectively, and to clarify the distinction between impingement avoidance and dislocation avoidance, kinematic and kinetic inputs for seven dislocation-prone activities were applied to finite element models of a contemporary 22-mm modular total hip reconstruction. Twenty-five cup placement positions (combinations of 30, 40, 50, 60, and 70 degrees of abduction with 0, 10, 20, 30, and 40 degrees of anteversion) were chosen to include the conventional 'safe zone' of 30-50 degrees of tilt and 5-25 degrees of anteversion. Activities studied were: rising from a low seat (toilet) and from a normal height chair, leg-crossing while seated, tying a shoe from a seated position, bending at the hip from an erect stance to retrieve an object on the floor (stooping), a standing pivot maneuver, and rolling over in bed. Neck-on-cup impingement occurred during one or more of the dislocation-prone activities at all 25 cup positions. Of the 175 combinations of cup position and kinetic challenge, dislocation and impingement events both occurred for 51 situations, while impingement occurred in 45 instances without dislocation, and dislocation occurred in 10 instances without impingement. Neither dislocation nor impingement was observed in the 69 other combinations of cup position and loading challenge. Kappa statistics showed dislocation and impingement, as outcome measures of activity-dependent challenges, exhibit little more than chance agreement. Therefore, the use of impingement range of motion (ROM) as a predictor of a given cup position's vulnerability to dislocation should be viewed cautiously.

Computer Simulation↗
PubMed2006

Measuring orthopedic implant wear on standard radiographs with a precision in the 10 microm-range.

The aim of this study has been to explore and verify whether the use of a previously designed Analysis-by-Synthesis algorithm is capable to precisely measuring implant wear. The abrasion of polyethylene particles is seen as the main reason for the loosening of prosthetic components in the hip. It lies in the sub-millimeter range, and precision is a crucial point in wear measurement. In the Analysis-by-Synthesis algorithm, the synthetic X-ray image of the implant is matched to its original X-ray projection. This intensity based approach and the use of X-ray images with their inherent high resolution allow principally precise measurements. Wear has been defined based on the estimated implant parameters and under minimization of the impact of the main sources of error. The latter was theoretically studied in a sensitivity analysis. The use of the algorithm was tested in vitro as well as in vivo. In experimental data, the accuracy and the impact of the pelvic position and orientation were studied. The precision was assessed using dual radiographs of 20 patients with total hip replacement. A standard deviation of 49 microm was found.

Equipment Failure Analysis↗
PubMed2005

Current concepts of metal-on-metal hip resurfacing.

The second-generation, metal-on-metal (MOM) bearing for total hip replacements was launched in the 1980s, and resurfacing followed in the mid-1990s. Remaining challenges include long-term bone remodeling of the femoral resurfacing and consideration of adverse MOM wear conditions. Precise understanding of manufacturing variables such as alloy types, bearing diameters, design tolerances, and surface finish is imperative in obtaining clinical consistency and safety in the patient. This review examines femoral fixation, bone remodeling, and wear studies of MOM implants and provides a brief overview of the latest outcome and retrieval data and how these data integrate with the in vitro wear studies.

Arthroplasty, Replacement, Hip↗
PubMed2003

Force track analysis of contemporary hip simulators.

In an earlier paper, the authors presented the first verified method of computation of slide tracks in the relative motion between femoral head and acetabular cup of total hip prostheses. The method was applied for gait and for two hip simulator designs, and in a subsequent paper, for another eight designs. In the present paper, the track drawn by the resultant contact force, the so-called force track, was studied in depth. The variations of sliding distance, sliding velocity and direction of sliding during a cycle, all of which are important with respect to wear, were computed for gait and for 11 hip simulator designs. Moreover, the product of the instantaneous load and increment of sliding distance was numerically integrated over a cycle. This integral makes it possible to compare clinical wear rates with those produced by hip simulators in terms of a wear factor. For the majority of contemporary hip simulators, the integral has so far been unknown. The computations revealed considerable differences, which are likely to explain the substantial differences in wear produced by the simulators. With the most common head diameter, 28 mm, the ranges for sliding distance per cycle, mean sliding velocity, total change of direction of sliding and integral were: 19.7-34.3 mm, 19.7-49.0 mm/s, 360-1513 degrees, and 17.4-43.5 Nm, respectively.

Computer Simulation↗
PubMed2002

A study of tissue interface membranes from revision accord knee arthroplasty: the role of T lymphocytes.

Despite four decades of advances in the design of orthopaedic devices aseptic loosening remains a major cause for the revision of total joint arthroplasty. This study used the techniques of immunohistochemistry and reverse transcription polymerase chain reaction to identify the inflammatory cell types, cytokines and chemokines within the interface tissue surrounding failed Accord Knee prostheses. Many T cells were identified within the tissue: however, the classical marker of activation, CD25 was expressed on very few cells. Molecular analysis failed to detect the synthesis of either Th1 or Th2 cytokines. These results suggest that the T cells are being actively recruited to the site of inflammation along the chemokine gradients but are not participating in a classical immune response.

Aged↗
PubMed2002

The incidence of revision of the metal component of total knee arthroplasties in different tibial-insert designs.

Seventy-one revisions of knee arthroplasty due to wear of modular tibial polyethylene inserts undertaken from May 1990 to May 1999 were reviewed. In 38 cases (53.5%), severe damage was noted that necessitated replacement of the metal components. This proportion was less than in a previous study (88.7%). All the cases were further divided into two groups based on the design of the tibial component, one group having mobile bearings and the other fixed. In only 17.7% of the mobile group was there a need to replace metal parts at revision, whereas 83.8% of the fixed group required such replacement, which is much more comparable to the previous study. Therefore, the incidence of revision of the metallic component of a total knee arthroplasty depends greatly on the design of the tibial components.

Aged↗
PubMed2003

In vitro assessment of proximal polyethylene contact surface areas and stresses in mobile bearing knees.

Wear of the polyethylene (PE) insert in total knee arthroplasty remains a significant problem. The generation of biologically active wear particles may ultimately affect implant longevity through osteolysis or premature/catastrophic PE failure. The rate and pattern of wear is influenced by many factors, including component geometry and individual loading conditions, which determine the contact surface area and kinematics of the reconstructed knee. Contact areas and stresses at the proximal femoral-PE insert interface and distal PE-tibial interface contact surface areas were measured in nine mobile bearing total knee designs at 0, 30, 60, 90 and 110 degrees of flexion at 3600 N (5 x body weight) using a standardized test method. Proximal and, to a lesser degree, distal interface contact area footprints decreased significantly with increasing flexion angle based on the conformity of the designs, resulting in a corresponding increase in the mean and peak stresses.

Elasticity↗
PubMed2001

Fractured Whiteside Ortholoc II knee components.

A comprehensive failure analysis was performed on 6 femoral components and 1 tibial component that fractured in service. All were Whiteside Ortholoc II total knee arthroplasty components, manufactured from cast cobalt-chromium-molybdenum alloy and porous coated. Fracture surface analysis revealed fatigue-induced failure in all cases. Most fractures occurred at regions of high stress concentration, such as sharp corners, sintered beads, and thin sections. Metallurgical examination showed significant variation in grain size, interdendritic carbides, and hardness between samples. In some cases, continuous carbide networks and voids were prominent at the bead-substrate interface. Patient weight and surgical placement were identified as contributory factors in component failure. Limitations of cast cobalt-chromium-molybdenum alloy in weight-bearing applications must be emphasized, particularly when important determinants, such as design, metallurgy, and specific clinical factors, are less than optimal.

Aged↗
PubMedDate not supplied

[Experimental analysis of neutral, asymmetric and constraint liners for total hip replacement: investigation of range of motion and protection against joint instability].

AIM: Recurrent dislocation after total hip replacement is a severe complication, which requires specific treatment and implants. The purpose of the present study was to compare a constraint liner with an elevated rim and standard liner regarding their range of motion and dislocation stability. METHOD: With a test device, range of motion until impingement (ROM (Imp)) and dislocation (ROM (Lux)) were experimentally analyzed using the above-mentioned insert types of a commercial total hip system. On the basis of movement combinations associated with dislocation, the ROM was determined. Further measuring parameter was the resisting moment against subluxation of the femoral head. RESULTS: The constraint liners showed clear restriction of the movements "internal rotation combined with 90 degrees flexion and 0 degrees adduction" and "external rotation with 10 degrees extension and 15 degrees adduction" of up to 20 degrees compared to the neutral liner. ROM (Imp) was only decreased by about 8 degrees with the elevated-rim liner. The constraint liners revealed the highest resisting moments in subluxation, however, at adequate orientation in the acetabular cup the elevated-rim liners provided a higher ROM (Lux) of up to 12 degrees. Both designs were superior to the neutral liner at retroversion and steep cup position regarding resisting moment and ROM (Lux). CONCLUSION: In case of insufficient soft tissue tension the use of constraint liners may increase the dislocation stability, however, in contrast to elevated-rim liners the impingement-free movement interval is clearly reduced. Thus, material damage and high shear stress in the bone interface can result. Therefore, constraint liners should only be used in exceptional cases.

Equipment Failure Analysis↗
PubMed2005

Assessing wear of the acetabular cup using computed tomography: an ex vivo study.

PURPOSE: To validate a clinically useful method for measuring acetabular cup wear using computed tomography (CT). MATERIAL AND METHODS: Eight uncemented acetabular cups were scanned twice ex vivo using CT. The linear penetration depth of the femoral component head into the cup and the thickness of the remaining polyethylene liner were measured in the CT volumes using dedicated software. Two independent examiners twice assessed each volume. The CT measurements were compared to direct measurements using a coordinate measuring device and micrometer measurements. RESULTS: Accuracy of wear measurements expressed as penetration depth was +/-0.6 and +/- 1.0 mm for the two examiners, respectively, with no significant differences between examiners, trials, and CT scans. Accuracy of measurements of remaining polyethylene was +/- 1.3 and +/- 1.0 mm, respectively, for the two examiners. Systematic differences between examiners were found, but no significant differences between trials and CT scans. These differences were due to different interpretations of metal artifacts in the volumes. CONCLUSION: The proposed CT method for evaluating wear as head penetration depth allows for reliable wear detection at a clinically relevant level. Measurements of remaining polyethylene on CT volumes are not as reliable as wear measurements owing to metal artifacts.

Device Removal↗
PubMed2006

A method of quantification of stress shielding in the proximal femur using hierarchical computational modeling.

Stress shielding is a biomechanical phenomenon causing adaptive changes in bone strength and stiffness around metallic implants, which potentially lead to implant loosening. Accordingly, there is a need for standard, objective engineering measures of the "stress shielding" performances of an implant that can be employed in the process of computer-aided implant design. To provide and test such measures, we developed hierarchical computational models of adaptation of the trabecular microarchitecture at different sites in the proximal femur, in response to insertion of orthopaedic screws and in response to hypothetical reductions in hip joint and gluteal muscle forces. By identifying similar bone adaptation outcomes from the two scenarios, we were able to quantify the stress shielding caused by screws in terms of analogous hypothetical reductions in hip joint and gluteal muscle forces. Specifically, we developed planar lattice models of trabecular microstructures at five regions of interest (ROI) in the proximal femur. The homeostatic and abnormal loading conditions for the lattices were determined from a finite element model of the femur at the continuum scale and fed to an iterative algorithm simulating the adaptation of each lattice to these loads. When screws were inserted to the femur model, maximal simulated bone loss (17% decrease in apparent density, 10% decrease in thickness of trabeculae) was at the greater trochanter and this effect was equivalent to the effect of 50% reduction in gluteal force and normal hip joint force. We conclude that stress shielding performances can be quantified for different screw designs using model-predicted hypothetical musculoskeletal load fractions that would cause a similar pattern and extent of bone loss to that caused by the implants.

Arthroplasty, Replacement, Hip↗
PubMed1998

Porosity reduction in acrylic cement is clinically irrelevant.

Evidence from studies on migration raises serious doubts regarding the part played by fatigue failure of acrylic bone cement in the genesis of aseptic loosening of the components of total hip arthroplasties. Moreover, the viscoelastic properties of cement raise serious doubts concerning the relevance of conventional laboratory fatigue studies to the in vivo behavior of acrylic cement. It is not surprising that there is considerable clinical evidence that reduction of porosity in acrylic cement is of no relevance to the long term outcomes of total hip arthroplasty. These matters remain controversial, and randomized prospective trials would be necessary to settle the issues. For various reasons, such trials are unlikely to be performed.

Arthroplasty, Replacement, Hip↗
PubMed2003

Stem fixation in revision total knee arthroplasty: a comparative analysis.

Methods of stem fixation are a controversial aspect of revision TKA. We sought to determine which technique was superior by reviewing 475 revision TKAs done between 1986 and 2000. Of these 475 revisions, 286 major component revisions were done using 484 extended stems for fixation. Patients who died, patients who had less than 2 years follow up, or patients who had diaphyseal engaging stems were excluded from the study. The final data set included 113 revision TKAs with 202 metaphyseal engaging stems. Of the 202 stems, 107 were cemented whereas 95 were press-fit metaphyseal engaging stems. One hundred one of these were femoral stems and 101 were tibial stems. Using a modified Knee Society radiographic scoring system, 100 (93%) of the 107 implants with cemented stems were considered stable, seven (7%) were categorized as possibly loose requiring close followup, and none were loose. Of the 95 implants placed with cementless stems, only 67 (71%) were categorized as stable. Eighteen (19%) were possibly loose requiring close followup and 10 (10%) were loose (two tibial and eight femoral implants). We currently would urge caution in using cementless metaphyseal engaging stems for fixation in revision TKA.

Aged↗
PubMed2004

Oxidized zirconium femoral components reduce polyethylene wear in a knee wear simulator.

Polyethylene wear remains a major problem that can jeopardize the long-term durability of prostheses used in total knee arthroplasty. Oxidized zirconium is a material that combines the strength of a metal with the wear properties of a ceramic. This study evaluated the wear rates of polyethylene inserts against oxidized zirconium femoral components. Three oxidized zirconium femoral components and three Co-Cr femoral components of identical geometry used in total knee arthroplasty were articulated against standard tibial components with modular tibial inserts made of noncross-linked ultra-high molecular weight polyethylene. Gravimetric and volumetric polyethylene wear rates were calculated after 5 million gait cycles on an AMTI knee wear simulator. Oxidized zirconium reduced polyethylene wear by 42% compared with Co-Cr alloy. This study shows that oxidized zirconium can reduce polyethylene wear substantially when used for fixed-bearing total knee arthroplasty.

Biocompatible Materials↗
PubMed2004

Fatigue crack propagation resistance of highly crosslinked polyethylene.

A higher degree of cross-linking has been shown to improve wear properties of ultra-high molecular weight polyethylene in laboratory studies. However, cross-linking can also affect the mechanical properties of ultra-high molecular weight polyethylene. Fatigue crack propagation resistance was determined for electron beam cross-linked ultra-high molecular weight polyethylene and compared with gamma irradiation cross-linked and noncross-linked polyethylene fatigue specimens. Crosslinking was done with different dosages of irradiation followed by melting. For one irradiation dose (50 kGy) extrusion and molding processes were compared. A fracture mechanics approach was used to determine how the degree of cross-linking affects resistance to crack propagation in ultra-high molecular weight polyethylene. Fatigue crack propagation resistance was reduced in proportion to the irradiation dose. The type of irradiation (gamma or electron beam) or manufacturing method (extrusion or molding) did not affect fatigue crack propagation resistance. The reduced fatigue strength of highly cross-linked ultra-high molecular weight polyethylene could lead to mechanical failure in conditions that are associated with cyclic local tensile stresses.

Case-Control Studies↗
PubMed2006

The basis for a second-generation highly cross-linked UHMWPE.

Highly cross-linked ultra-high molecular weight polyethylene (UHMWPE) decreases wear at the hip by more than 50% compared with conventional UHMWPE. However, melted highly cross-linked polyethylene may be susceptible to fatigue cracking, and annealed highly cross-linked polyethylene may be susceptible to in vivo oxidation. The second-generation highly cross-linked UHMWPE (X3 HXPE) uses a sequential irradiation and annealing process. It preserves mechanical strength properties and has the highest survivorship in functional fatigue testing. The free radical content is low, and its performance under accelerated aging is the same as virgin UHMWPE. Hip simulator studies with 32-mm acetabular components demonstrated 97% wear reduction compared with conventional UHMWPE, and 62% compared with a clinically successful first-generation annealed highly cross-linked polyethylene. The crystallinity, density, and tensile strength of the X3 HXPE material was unchanged by oxidative challenge. X3 HXPE material articulating on cobalt-chromium alloy yields a volumetric wear rate very similar to that of metal-on-metal articulations, but eliminates the concerns of metal ion release. Wear particles generated from the X3 HXPE were the same size as those produced from conventional UHMWPE. Preliminary results suggest X3 HXPE can be used for cups larger than 36 mm.

Equipment Failure Analysis↗
PubMed2006

A biomechanical assessment of infra-laminar hooks as an alternative to supra-laminar hooks in thoracolumbar fixation.

STUDY DESIGN: Biomechanical study, using human cadaveric spines, of two types of posterior fixation in the thoracolumbar spine. OBJECTIVES: To compare fixation in the thoracolumbar spine using pedicle screws combined with infra-laminar hooks (at both the cranial and caudal ends of the same vertebra) with fixation using pedicle screws alone. SUMMARY OF BACKGROUND DATA: The standard method of using laminar hooks is to place supra-laminar hooks at the level above the vertebra being fixed by the cranial pedicle screws, and infra-laminar hooks at the level of the vertebra receiving the caudal pedicle screws. However, using this method, a single normal motion segment is killed. In the proposed technique, infra-laminar hooks will be used at the same level as the cranial pedicle screws, thus sparing the superior adjacent segment. METHODS: PEDICLE SCREW LOOSENING TEST: Nine vertebrae (T9-L2) had pedicle screws inserted into both pedicles. On one side, the pedicle screw was connected to a fixation rod, while on the other side the pedicle screw was combined with an infra-laminar hook and connected to a rod. The rod on one side was then pushed with increasing force until loosening of the screw. The same test was repeated on the other rod until loosening of the screw. The reverse test (i.e., pulling until loosening) was done in a similar manner on another nine vertebrae. BIOMECHANICAL STIFFNESS TEST: Eight spines (T12-L2) were biomechanically tested in: axial compression, flexion, extension, left and right lateral bending, and left and right axial torsion. This sequence was applied to: 1) the intact spine; 2) after applying pedicle screws and infra-laminar hooks with rods to the destabilized spine; and 3) after removal of the hooks (with the pedicle screw and rods still inserted). From the load-deformation curves obtained, stiffness values were calculated. RESULTS: PEDICLE SCREW LOOSENING TEST: The pedicle screw loosening tests showed that a pedicle screw combined with an infra-laminar hook offers significantly greater fixation strength as compared to a pedicle screw alone. Biomechanical stiffness test. Fixation by pedicle screws combined with infra-laminar hooks, placed on the vertebra fixed by pedicle screws at both the cranial and caudal ends, offered a stiffer construct as compared to fixation by pedicle screws alone. CONCLUSIONS: This method offers a firm construct without sacrificing a normal motion segment.

Bone Screws↗