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PubMed2007

Palmitoylation: policing protein stability and traffic.

Palmitate modifies both peripheral and integral membrane proteins and its addition can be permanent or transient, which makes it unique among the lipid modifications of proteins. The presence of palmitate on a protein affects how the protein interacts with lipids and proteins in a membrane compartment, and the reversibility of palmitoylation allows different modes of trafficking between membrane compartments. Here, we review recent studies that have provided insights into the mechanisms that mediate the functional consequences of this versatile modification.

Acylation↗
PubMed1995

Letters from California--the safety police.

I am sure many people imagine the United States of America as the land of the free, where people can do what they want unfettered by unnecessary rules, regulations and taxation. Unfortunately, the truth is very different and there are as many rules and regulations in the USA as almost anywhere else, and in some cases they are more complex since regulations come from both the federal government and the state government. Both may pass similar laws which differ in small degrees so there may be considerable areas of overlap but also considerable differences between the federal and state regulations. For dentists, a particular area of concern in recent years has been the agency known as OSHA, the Office of Safety and Health Administration.

California↗
PubMed2002

Supporting and policing mothers: an analysis of the disciplinary practices of health visiting.

AIM: This paper draws on the notion of disciplinary power developed by Michel Foucault to discuss whether the professional practices inherent in British health visiting can be understood in terms of support or surveillance. BACKGROUND: The notion of disciplinary power embedded within Foucault's writings has been widely applied to the sociological analysis of health care professions. While a number of studies have focused on nursing practice, there has been little empirical work developing these ideas in the context of British health visiting. METHODS: A qualitative approach using interviews with 24 health visitors and 16 women who had experienced domestic violence was used. For reasons of confidentiality, the women were not matched to the health visitors. Data analysis was continuous with data collection and led to identification of a number of categories. The theoretical framework of feminist poststructuralism underpinned the analysis. FINDINGS: The women who participated in this research described their engagement in a number of disciplinary practices. These included the discursive production of themselves as good mothers, subjects and objects of the health visiting gaze, as well as their practices of resistance to health visiting work. Analysis of the health visitors' interview data provided further evidence concerning the exercise of disciplinary power in their everyday work of providing support and health care to women and children. CONCLUSIONS: The paper highlights tensions within the health visitor's role between welfare and surveillance, as well as differences between lay and professional perspectives.

Community Health Nursing↗