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PubMedDate not supplied

Use of the Hickman catheter for the treatment of lower extremity infections.

The authors discuss the use of a cuffed, Silastic catheter, which can be of great value in the reduction of morbidity when dealing with lower extremity infections. When a patient's condition demands the use of long-term antibiotic and/or aminoglyoside therapy, this indwelling central venous catheter can allow easy access to the vascular system and markedly decrease the amount of time the patient has to stay in the hospital. This form of therapy involves the patient in the treatment and displays no mortality and minimal morbidity associated with catheter placement and care.

Anti-Bacterial Agents↗
PubMed1983

The use of the Papineau bone-grafting technique in salvage of the infected total joint implant.

The development of osteomyelitis after first metatarsophalangeal total implant-arthroplasty can be a complication encountered by any foot surgeon. The postoperative course is often long with a guarded to poor prognosis. The authors present a salvage procedure for this surgical complication utilizing aggressive surgical debridement followed by an autogenous bone graft. The technique, as described by Papineau, was developed to shorten hospitalization time and reduce deformity. A case presentation is given to illustrate the successful use of this procedure in the treatment of postoperative osteomyelitis of the foot without systemic antibiotics.

Adult↗
PubMed1976

[Change of pathogen in infections since 1958 (author's transl)].

Infections with proteus, pseudomonas, klebsiella and enterococci have increased significantly in the period of this report. The question of hospital hygiene, especially in intensive care wards, must therefore be given increased attention. Uncritical prophylaxis and treatment with antibiotics must be rejected. Attempts to improve the cellular and humoral defense of patients with reduced resistance would be worth while. To achieve progress, there must be a close co-operation between specialists in infection, hygienists, microbiologists, pharmacologists and immunologists. The activity of the specialists in infection is no longer exclusively confined to the isolated "epidemic ward", but includes advising clinicians in the various departments with regard to control of infection in the widest sense, and consequently a close co-operation with all clinical medical disciplines.

Adult↗
PubMed1977

Studies on quinoline derivatives and related compounds. 5. Synthesis and antimicrobial activity of novel 1-alkoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids.

A series of novel 1-alkoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids was synthesized and screened as antimicrobial agents. The most active compounds in vitro against gram-negative microorganisms and Staphylococcus aureus were 1,4-dihydro-1-methoxy-6,7-methylenedioxy-4-oxo-3-quinolinecarboxylic acid (22), 1,2,6,9-tetrahydro-6-methoxy-9-oxofuro[3,2-f]quinoline-8-carboxylic acid (30, and 2,3,6,9-tetrahydro-6-methoxy-3-methyl -2,9-dioxothiazolo [5,4-f]quinoline-8-carboxylic acid (34). These compounds had antigram-negative activity comparable to that of the corresponding N-ethyl derivatives 1, 2, and 4. Their serum levels and urinary recovery rates in rats, however, were significantly improved relative to the latter compounds (1,2, and 4).

Animals↗
PubMed1986

In vitro and in vivo study of stone formation by Corynebacterium group D2 (Corynebacterium urealyticum).

Corynebacterium group D2 inoculated into normal human urine formed struvite crystals and an increase in pH and ammonium concentration after 24 h of incubation. Zinc disks dipped into a broth culture of this microorganism and inserted into the bladders of rats produced stones with a mean weight of 12.5 mg (ranging from 1 to 57.7 mg) after 12 days. Analysis of the infrared spectrum determined the stones to be composed of struvite. From these results its seems that stone formation by Corynebacterium group D2 may be possible both in vitro and in vivo, which may confirm a previous report involving these bacteria in human clinical encrusted cystitis.

Animals↗
PubMed1964

BACTERIOLOGICAL COMPLICATIONS FROM THE USE OF URETHRAL INSTRUMENTS: PRINCIPLES OF PREVENTION.

Guidance by bacteriologists and changes in theatre and ward disciplines have greatly improved the results of urological surgery in recent years. The most noteworthy successes have been in treatment of chronic retention with renal failure, and in prevention of the bacteraemia which may occur following removal of the post-operative catheter or the passage of an instrument to dilate a stricture. It is hoped that safer urethral instrumentation may also reduce the incidence of chronic pyelonephritis.

Anuria↗
PubMed1987

Subperiosteal and Bezold's abscesses complicating cholesteatoma: a case report.

A case of subperiosteal and Bezold's abscesses that occurred in a 60-year-old man with cholesteatoma has been described and the literature reviewed. Bezold's abscess is rarely seen in the current era of antibiotics. The simultaneous occurrence of a subperiosteal abscess in association with cholesteatoma, particularly in an adult, makes this case even more unusual. Although antibiotics have reduced the complications associated with acute otitis media, rare complications still occur and should be recognized by the otolaryngologist.

Abscess↗
PubMed2003

[Pyomyositis].

Pyomyositis is a bacterial infection of skeletal muscle. It is a rare condition which cannot easily be diagnosed. A fatal case of pyomyositis in a 78-year-old man is presented. The clinical signs and diagnostics of pyomyositis are discussed.

Aged↗