Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “PAINT”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,099 records · Page 61Linked to original sources
PubMed2002

Bone marrow hypoplasia and intestinal crypt cell necrosis associated with fenbendazole administration in five painted storks.

Five painted storks were treated with fenbendazole for 5 days for internal parasitism. Four birds died following treatment. Profound heteropenia was a consistent finding in all samples evaluated; additionally, the 1 surviving bird had progressive anemia. Consistent necropsy findings in the 4 birds that died were small intestinal crypt cell necrosis and severe bone marrow depletion and necrosis. Fenbendazole has been associated with bone marrow hypoplasia and enteric damage in mammals and other species of birds. The dosages of fenbendazole used in birds are often substantially higher than those recommended for mammals, which may contribute to bone marrow hypoplasia and intestinal crypt cell necrosis associated with fenbendazole administration in birds.

Animals↗
PubMed1993

Visual preferences of preschool children for abstract and realistic paintings.

40 children ages 2 or 3 years were asked to express preferences for 9 abstract and 9 realistic paintings on two separate occasions. Children showed no clear preferences and these were stable over occasions. Their drawings were classified in the scribble stage. These results were consistent with downward extensions of aesthetic preference theories. Implications for the usual environments of young children were discussed.

Art↗
PubMed1980

Herpesvirus-like infection in a painted turtle (Chrysemys picta).

A painted turtle (Chrysemys picta) which died in captivity had marked necrosis in the liver and lungs with numerous intranuclear inclusion bodies in hepatocytes and respiratory epithelial cells. Electron microscopy revealed herpesvirus-like particles in cells in affected tissues.

Animals↗
PubMedDate not supplied

Induction of cell-mediated immunity in the mouse: circumstantial evidence for highly immunogenic antigen in the regional lymph nodes following skin painting with contact sensitizing agents.

This paper describes an investigation of why contact sensitizing agents cause strong cell-mediated immunity. Contact sensitivity was induced in mice by painting the skin with 4-ethoxymethylene-2-phenyloxazolone (oxazolone), and measured by the increase of ear thickness following challenge six days later. Reactivity was transferred by taking the regional lymph node cells from mice 18 h after immunization and injecting them into the footpads of recipients. This "18-h transfer" has several characteristics. As few as 2 X 10(4) cells were effective. The donor lymph node cells were best taken one to three days after immunization, were less effective on day 4 and virtually inactive by day 7. The recipients developed contact sensitivity when challenged on day 4, but lacked sensitivity when challenged on days 1 and 2 after transfer. The transferred cells were still active after treatment with anti-theta serum and complement. They also resisted 2,000 R in vitro, mitomycin, vinblastine, and inhibitors of protein synthesis such as emetine, cycloheximide and puromycin. The transfer was prevented by treatment with trypsin, freeze-thawing, and heating at 56 C. Plasma membranes were also immunogenic. The evidence suggests that the "18-h transfer" is a special type of active immunization, not due to ordinary free oxazolone, and that the agent is present within the lymph node in a free oxazolone, and that the agent is present within the lymph node in a specially immunogenic location or form.

Animals↗
PubMed1996

NTP Comparative Initiation/Promotion Skin Paint Studies of B6C3F1 Mice, Swiss (CD-1(R)) Mice, and SENCAR Mice.

In 1983, an ad hoc panel on chemical carcinogenesis testing and evaluation recommended additional methods that should be used by the National Toxicology Program (NTP) for the detection and evaluation of chemical carcinogens. One recommendation was that there should be an increased emphasis on short-term tests to detect agents that do not exert genetic effects such as some promoting agents. Initiation/promotion models have been used routinely to identify chemicals with promoting potential and to study tumorigenesis. In one model, a topical subcarcinogenic dose of a chemical is first applied to the back of the skin (initiation) followed by repeated topical applications of one or more chemicals (promotion) and the skin is monitored for tumor development. Mouse skin has been shown to be more responsive (i.e., develops tumors using this protocol) than other commonly used laboratory rodent models. However, not all mouse strains are equally sensitive. The skin tumor response of the B6C3F1 mouse using the initiation/promotion protocol was not known. Since the B6C3F1 mouse is commonly used in NTP carcinogenesis studies and much is known of its biology and response to chemical carcinogens, known initiators and promoters were used to compare the tumor response sensitivity of B6C3F1 mouse skin to that of two often-used responsive strains, Swiss (CD-1(R)) and SENCAR mice. The combination of 7,12- dimethylbenz(a)anthracene (DMBA) initiation and 12-O-tetradecanoylphorbol-13- acetate (TPA) promotion was selected because this pair is routinely used to study tumorigenesis. However, DMBA requires metabolic activation to achieve initiation and it was possible that the B6C3F1 mouse metabolism might not make this conversion (DiGiovanni and Juchau, 1980). Therefore, a second study was conducted using N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), a direct acting carcinogen, as the initiator. MNNG is not used as frequently for mouse skin studies as is DMBA. In addition to the promoter TPA, benzoyl peroxide (BPO), a non-phorbol ester and known promoter after DMBA initiation, was also used (Slaga et al., 1981). Each initiating chemical was used in combination with each promoting chemical as described on the study design table below. Additional groups of male and female mice of each strain were treated with repeated applications of acetone (vehicle control), repeated applications of promoter (TPA or BPO) without prior initiation treatment (promoter reference controls), or a single application of the initiator (DMBA or MNNG) followed by repeated applications of acetone (initiator controls). All three strains of mice demonstrated sensitivity by developing skin tumors after topical application of the chemicals under study (DMBA, MNNG, TPA, and BPO). The most sensitive of the three strains appeared to be SENCAR mice, in the sense that lower doses of the test chemical were generally required to produce effects equivalent to those in the other two strains. Skin tumors also tended to develop earlier and with greater multiplicity in SENCAR mice than in the other two strains. By these criteria, the overall sensitivity of Swiss (CD-1(R)) mice was intermediate, and B6C3F1 mice showed the least overall sensitivity to dermal carcinogenicity. In response to recommendations regarding specific short-term tests and also on the skin tumor response sensitivity of various initiators and promoters, SENCAR mice would be the most acceptable strain to use for such studies. Though the B6C3F1 mice were less responsive in the skin initiation/promotion protocol, promotion data from this strain may, at times, be of more use in explaining mechanisms of tumor development (e.g. when there is a strain specific response observed in 2-year carcinogenicity studies or effects on melanocytes are suspected). See the full report or study abstract for table of Study Design for the 1-Year Comparative Initiation/Promotion Skin Paint Studies. The 1-year complete carcinogen studies used repeated applications of low concentrations of the carcinogens DMBA and MNNG. The skin tumor response in aln all three strains under these conditions was more similar than in the initiation and promotion studies. There was a high incidence of skin tumors in all three strains with both carcinogens. More B6C3F1, and SENCAR mice developed skin tumors and averaged more tumors per mouse than did Swiss (CD-1®) mice. Skin tumors developed earlier in SENCAR mice than in B6C3F1 and Swiss (CD-1®) mice. Although B6C3F1 mice exhibited the lowest overall sensitivity to the initiation/promotion protocol when compared to Swiss (CD-1®) and SENCAR mice, the response of B6C3F1 mice was similar to Swiss (CD-1®) and SENCAR mice for complete carcinogen studies.

Journal Article↗
PubMed2002

Efficacy of a novel, nontray, paint-on 18% carbamide peroxide whitening gel.

A double-blind, 3-week, randomized, placebo-controlled, parallel-group clinical trial was conducted to evaluate the tooth-whitening efficacy of a novel nontray, "paint-on" liquid whitening gel containing 18% carbamide peroxide (Colgate Simply White Clear Whitening Gel). Efficacy was based on measured Vita tooth-shade scores collected at baseline and after 2 and 3 weeks of product use. Eighty healthy volunteers were balanced into 2 groups based on gender, age, and shade scores (A3 or higher). The duration of product usage was 30 minutes, twice daily, for 3 weeks. Results from this clinical study showed that subjects' teeth in the liquid whitening gel-treated group exhibited an overall mean 3.84-shade improvement and a 3.5-shade difference compared with teeth in the placebo gel group (statistically significant, P < .05) after 3 weeks. Furthermore, this improvement exceeds the minimum requirement to claim "clinical efficacy" as established by the "Guidelines for the Acceptance of Peroxide-Containing Oral Hygiene Products," published by the American Dental Association in 1994. Therefore, it can be concluded that Colgate Simply White Clear Whitening Gel significantly whitens teeth.

Adolescent↗
PubMed2001

A low-level X chromosome mosaicism in mares, detected by chromosome painting.

Fluorescence in situ hybridization with the use of the equine X whole chromosome painting probe was carried out on chromosome spreads originating from three mares with poor reproductive performance (infertility, miscarriage or stillbirth). The numbers of analysed spreads were high (105, 300 and 480) and in all three mares a low frequency of mosaicism was identified. The mares had the following karyotypes: 64,XX/63,X/65,XXX (93.6%/5.7%/0.7%), 64,XX/63,X (98.9%/1.1%) and 64,XX/63,X (94.3%/5.7%). The incidence and importance of the low percentage X chromosome mosaicism are discussed.

Journal Article↗
PubMed2005

Use of Corel Photo-Paint for chromosome karyotyping: an inexpensive, semiautomatic approach.

Karyotyping has become an important component of cytogenetic analysis. Both manual and automatic karyotyping procedures are in use all over the world, but both have drawbacks. Manual karyotyping is inexpensive, but highly time-consuming and labor-intensive. Automatic karyotyping, on the other hand, saves time but is expensive and also does not always provide consistent or reliable results. Thus, in order to cope with these problems, a semiautomatic approach for karyotyping was developed. In this technique, a commonly used graphics software program, Corel Photo-Paint, is used for karyotyping. With this technique one can cut, paste, move, rotate, and arrange the chromosomes to form a karyotype. In addition, one can increase the resolution and sharpness of chromosome bands, which facilitates the classification of chromosomes. The comparative advantages of this semiautomatic approach are discussed in detail.

Journal Article↗
PubMed1990

Reassessment of two apparent deletions of chromosome 16p to an ins(11;16) and a t(1;16) by chromosome painting.

Two apparent deletions of the short arm of chromosome 16 were studied by in situ hybridisation using biotinylated DNA from a chromosome 16 specific cosmid library (chromosome painting). One abnormality was delineated as a t(1;16)(p36;p12) and the other as a ins(11;16)(q13;p13.13p13.3). Apparently unbalanced de novo abnormalities detected by classical cytogenetic procedures should be interpreted with caution. In situ hybridization using DNA from chromosome specific libraries provides the appropriate technology to delineate such abnormalities.

Adult↗
PubMed1990

Allergic contact dermatitis to colophony included in the formulation of flexible collodion BP, the vehicle of a salicylic and lactic acid wart paint.

The authors describe two cases of allergic contact dermatitis to colophony included in the formulation of flexible collodion BP, the vehicle of a wart paint. Patch and repeated open application tests confirmed absence of contact allergy to other constituents. The patients were known to be allergic to various adhesive plasters. The use of flexible collodion USP, which does not contain colophony, is highly advisable whenever possible.

Adult↗
PubMedDate not supplied

A nonparametric comparison of monomolecular growth curves: application to western painted turtle data.

Intractable distributional assumptions are generated in parametric analyses comparing groups of subjects described by nonlinear growth models. The distributional situation becomes more complex when pointwise mean curves best describe group growth (instead of curves based on mean parameters). An interval specific randomization test is developed to handle monomolecular growth models. The need for the technique was motivated by a study describing longitudinal growth data from the annuli on abdominal scutes of groups of western painted turtles. The analyses indicate that female turtles grow larger than male through the first seven years of life. The analytical procedures developed for these turtles are useful in the description and analyses of many other growth processes.

Animals↗
PubMed1988

Liquid nitrogen and salicylic/lactic acid paint in the treatment of cutaneous warts in general practice.

Patients with common hand warts and simple plantar warts attending a general practice wart clinic in Northern Ireland were assigned to one of three treatment groups - liquid nitrogen applied weekly, daily application of wart paint (lactic acid one part, salicylic acid one part, collodion four parts), or a combination of the two. Combination therapy cured 87% of common hand warts over a six week period, and was significantly more effective than either agent used separately (P<0.05). The results for simple plantar warts were disappointing and no treatment regimen proved to be significantly better than any other. These treatments were cheap, compliance and tolerance were good, and the six month recurrence rate was minimal. Given the likelihood that warts will multiply if left untreated we would recommend early active treatment for this condition.

Adolescent↗
PubMed1979

The production of contact sensitivity by the injection into the footpads of recipients of the lymph node cells from mice 1 day after painting the skin with contact sensitizing agent: requirement for matching at the major histocompatibility complex between donor and recipient mice.

Donor mice were painted on the skin of the abdomen with the contact sensitizing agent, oxazolone. One day later 2-5 x 10(6) cells from the regional lymph nodes were injected into the footpads of recipient mice. Contact sensitivity was detected 6 days later by challenging the ears of the recipients and measuring the increase of thickness at 24 h. Good contact sensitivity was obtained when CBA cells were injected into CBA mice and BALB/c cells injected into BALB/c mice; the injection of BALB/c (H-2d) cells into CBA (H-2k) mice and vice versa failed to give rise to contact sensitivity. Hybrid F1 cells gave intermediate responses. The contact sensitivity caused by the injection of small numbers of lymph node cells into the footpad is interpreted as a mode of active immunization and the present results show that this only occurs when there is genetic matching at the major histocompatibility complex between the donor and the recipient mouse.

Animals↗
PubMed1981

[Microbial settlement of paint- and building-materials in the sphere of drinking water. 8. Communication: Experimental examination of epoxy resin in laboratory tests (author's transl)].

Different observations in potable water reservoirs with epoxy resins induced us to investigate some paintings. Commercial products of known and unknown constituents were tested. Some commercial products recommended for the use in potable water sphere produced microbial slime while others didn't. Solvents, accelerators and even both of the building compounds of the epoxy resin, if they are not used in the stoichiometric mixing ratio, may produce microbial slime. The temperature of preparation has an important influence on the slime formation.

Bacteria↗
PubMed1981

Tumors of the anal region induced in mice painted with methylazoxymethanol acetate.

The carcinogenicity of methylazoxymethanol acetate (MAM acetate) was examined in 91 BALB/c mice by painting it on the anal region. Carcinomas and adenomas of the perianal sebaceous gland were induced in 23 of 24 male (96%) and 16 of 30 female (53%) mice and keratoacanthoma developed in one of 24 male mice within 30 weeks after treatment with MAM acetate. Vascular tumors of the liver and fat issue of the abdominal cavity also developed in 16 of 24 male (67%) and 3 of 30 female (10%) mice treated with this drug. Microscopic adenocarcinomas were found in the rectal mucosa of 3 of 24 male mice adjacent to the anorectal junction. The sex difference in the incidence of tumors is briefly discussed.

Adenoma↗