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Results for “LEIOMYOSARCOMA”

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PubMed1987

[Leiomyosarcoma of the inferior vena cava].

We report a case of a grade II leiomyosarcoma of the suprarenal vena cava in a 56-year-old man. It was discovered during exploratory laparotomy for lower back and abdominal pain associated with intermittent renal failure of 8 months' duration and recent exertional dyspnea. The tumor was completely resected, with reimplantation of the right renal vein. Adjuvant radio- and chemotherapy were administered. The postoperative course was uneventful and the patient has been disease-free during follow-up of 12 months. The difficulties of preoperative diagnosis and surgical treatment of leiomyosarcoma of the inferior vena cava are discussed.

Combined Modality Therapy↗
PubMed1987

[Leiomyosarcoma of the gallbladder].

A case of leiomyosarcoma of the gallbladder in a 55-year-old woman is presented. The definitive diagnosis of leiomyosarcoma according to the histologic structure of the tumor was made by electron-microscopic study. Ultrastructure of this tumor type is characteristic of presence of myofilaments and cytoplasmic vesicles in the cytoplasm.

Female↗
PubMed1986

[A case of prostatic leiomyosarcoma].

A case of a 19-year-old male with leiomyosarcoma of the prostate is reported. He visited our hospital with the chief complaint of urinary retention in December, 1983. Following overall examination, needle biopsy of the prostate gland was performed with the suspicion of sarcoma. Histology of the prostate revealed leiomyosarcoma. Two courses of combined chemotherapy were given, but the tumor continued to enlarge. The patient died in April, 1984, 5 months after the appearance of the first symptom.

Adult↗
PubMed1986

Torsion of leiomyosarcoma of Meckel's diverticulum.

A rare case report of leiomyosarcoma of Meckel's diverticulum, which caused torsion and strangulation of the diverticulum, is presented. The clinical picture was similar to acute appendicitis, which was the working diagnosis when the 42-yr-old Arab woman was sent to surgery. Although rare, leiomyosarcoma is the most common tumor of Meckel's diverticulum, and has to be considered in the differential diagnosis of right lower abdominal pain.

Abdomen, Acute↗
PubMed1985

[Leiomyosarcoma of the small intestine. Apropos of 3 cases].

The authors report three cases of leiomyosarcomas of the small intestine and review the literature on this subject. Leiomyosarcomas of the small intestine are rare tumours, representing 0.2% of all malignant tumours of the gastrointestinal tract. These large, round, hypervascular tumours are derived from smooth muscle cells in the intestinal wall and often develop extra-luminally. The malignant nature is often difficult to confirm on the histological examination. The clinical signs often only appear when the tumour has reached a large volume. It is rare to make the diagnosis pre-operatively, despite the use of a number of investigations. Arteriography is the most reliable examination. Spread of the disease is essentially haematogenous. The malignant tumour invades adjacent organs, causes hepatic metastases and peritoneal seedlings and tends to recur locally. The treatment is essentially surgical and the prognosis varies according to the size of the tumour, its grade, its activity and its degree of extension. The 5-year survival of all forms of the disease varies between 20 and 50%, according to the series.

Aged↗
PubMed1985

Leiomyosarcoma of the prostate in adults.

Three cases of prostatic leiomyosarcoma and a brief review of the literature are presented. The authors emphasize the differences in clinical features, management and prognosis between the sarcomas occurring in childhood and the rarest leiomyosarcoma of elderly patients.

Aged↗
PubMed1985

[Primary leiomyosarcoma of the lung--a case report].

One case of primary leiomyosarcoma of the lung is presented. Leiomyosarcoma of the lung is a rare tumor. Of 83 cases reported in the literatures, 54 were recorded in detail. The incidence of the disease in the male is higher than that in the female. Children, adolescents and young adults may be involved. Its clinical and X-ray manifestations are similar to those of lung cancer. The diagnosis is established by pathologic examination. Direct visualization, biopsy and brushing during bronchoscopy are important methods for preoperative diagnosis. The chance of positive sputum cytology is very small. The pathologic features of this disease are emphasized. It is suggested that surgery be more effective for this tumor than the other lung cancers.

Female↗
PubMed1977

Establishment of a human leiomyosarcoma cell line.

A cell line designated SKN was established from the human uterine leiomyosarcoma of a 52-year-old female. The cell line has grown well and the serial passages were successively carried out 82 times within 12 months. The monolayer cultured cells revealed anaplastic and pleomorphic features, and they multipled rapidly without contact inhibition. Electron microscope studies revealed myoibrils but no virus-like particles, while chromosomal studies showed that all cultured cells were hyperploid, the modal number was 112, and the marker chromosome was present. The cells were transplanted into an immune-depressed hamster cheek pouch and produced a histological leiomyosarcoma resembling the original tumor.

Animals↗
PubMedDate not supplied

[An unusual cause of recurrent pericarditis: esophageal leiomyosarcoma (author's transl)].

A supposed primary and cortico-sensitive pleuropericarditis in a 33-year-old woman with an apparent recovery of 9 months, revealed an esophageal leiomyosarcoma with a fatal issue following tumoral and purulent invasion of the mediastinum with an esophagobronchial fistula. Pericardis of tumoral origin may appear as a benign cryptogenetic affection sensitive to corticotherapy. Acquired esophagotracheobronchial fistulae are usually of neoplastic origin and the prognosis is extremely severe, survival being rarely more than three months. 69 cases of esophageal leiomyosarcoma have been reported in the published literature, but survival was prolonged in some patients treated surgically. Investigations for possible esophageal lesions should be conducted in all cases of pericarditis of unknown origin.

Adult↗
PubMed1983

Pulmonary metastatic leiomyosarcoma coexisting with pulmonary chondroma in Carney's triad.

The diagnosis of Carney's triad requires the coexistence of at least two of three rare disorders, including gastric epithelioid leiomyosarcoma, pulmonary chondroma, and functioning extra-adrenal paraganglioma. Seventeen cases have been reported so far, occurring predominantly in young female patients. We report herein the 18th case of this entity and the first case, to our knowledge, where pulmonary metastases from a gastric leiomyosarcoma coexisted in a patient with benign pulmonary chondromas.

Adult↗
PubMed1984

[Cutaneous leiomyosarcoma].

Primary cutaneous leiomyosarcomas are rare mesenchymal skin tumors with relatively good prognosis and low risk of metastasis if there is no subcutaneous involvement. A 48-year-old patient with a primary cutaneous leiomyosarcoma of ten years duration is described. Therapy and differential diagnosis are discussed.

Breast Neoplasms↗
PubMed1983

Leiomyosarcoma of iliac veins.

Although malignant neoplasm of the venous system is rare, leiomyosarcoma of large veins (predominantly the inferior vena cava) constitutes more than 75% of this condition. Symptoms are subject to tumor location and stenosis or obstruction of the venous system. This report describes the cases of two patients with leiomyosarcoma originating in large veins. Venography is extremely important for diagnosis, however computerized axial tomography with dye enhancement is helpful to depict the neoplastic nature of this condition. Excision and replacement with autogenous vein or artery will provide better long-term patency.

Aged↗
PubMed1983

[A case of renal leiomyosarcoma].

A case of renal leiomyosarcoma is presented. A 65-year-old man was admitted with asymptomatic gross hematuria. On excretory pyelography, the left kidney was not visualized. Computed tomography showed a left intrarenal mass. The patient underwent left radical nephrectomy. The histological diagnosis was leiomyosarcoma probably originating from the left renal pelvis.

Aged↗
PubMed1984

[Leiomyosarcoma of the rectum--a case report].

Tumors of smooth muscle origin are relatively uncommon in the rectum. Patients with leiomyosarcoma are very infrequently encountered. The patient was a 59-year-old Japanese male, who presented complaining of difficulty of defecation and melena. Rectal examination revealed an elastic hard and smooth-surfaced tumor of walnut size at 4 cm on the left antero-lateral wall. Needle biopsy was performed and the tumor was resected trans- sacrally. Histopathologically the tumor, was diagnosed to be leiomyosarcoma. Although the patient received no postoperative chemotherapy or irradiation, he is living without any symptoms or signs of recurrence 5 years and 6 months after the surgery.

Biopsy, Needle↗
PubMed1981

[Leiomyosarcoma--a rare malignant renal neoplasm (author's transl)].

Leiomyosarcomas are extremely rare renal tumors. As to symptoms, they do not differ from other malignant neoplasms of the kidney. In one case diagnosis revealed a sclerosed tumorous necrosis. Therapeutically, it is also in leiomyosarcoma that surgery is the approach of choice since other methods of treatment failed to show significant advantages. Bearing in mind the more fulminant growth of sarcomas, the prognosis is in general poorer than with the remaining malignant renal neoplasms.

Aged↗
PubMed1983

Leiomyosarcoma of the mediastinum.

Leiomyosarcomas of the mediastinum are rare tumours, with only four cases reported in the literature. In the absence of any specific clinical pointer for diagnosis, proof comes through histopathologic study. One case of leiomyosarcoma of the superior mediastinum is reported here because of its rarity and an interesting histopathology.

Humans↗
PubMed1981

Leiomyoma and leiomyosarcoma of the digestive tract--a report of 45 cases and review of the literature.

The authors discuss the general and radiologic characteristics of leiomyomas and leiomyosarcomas, based on experience with forty-five cases involving the digestive tract and a review of over one thousand cases reported in the literature. Thirty-six leiomyomas (oesophagus 9, stomach 18, small intestine 9) and nine leiomyosarcomas (oesophagus 2, stomach 2, small intestine 4, colon 1) were observed and compared with reports from the literature. Leiomyomas of the oesophagus lend themselves to radiologic surveillance since there is no tendency for lesion degeneration in this location. Leiomyomas of the stomach are frequently asymptomatic and discovered following radiologic or endoscopic examination. With involvement of the small intestine, the most sensitive radiologic examination remains angiography, even though the information provided does not allow evaluation of the evolution of the tumour. Localization in the colon remains rare.

Adult↗
PubMed1982

Prognostic factors of 28 leiomyosarcomas of the small intestine.

Leiomyosarcoma of the small intestine is a rare tumor, comprising 0.2 per cent of all malignant tumors of the gastrointestinal tract. The charts of 28 patients were reviewed; the outstanding characteristics were a slow growing, but sometimes, fast growing locally malignant lesion, more than half being in the ileum. Arteriograms are better than a roentgenographic series of the small intestine for diagnosis. Adjuvant therapy is probably of no benefit. Between histologically benign leiomyomas and malignant leiomyosarcomas, there is a third group with histologic manifestations of malignancy and good prognosis, seven of ten patients surviving to five years. To define this group, we need an association of these three factors, duration of symptoms for more than one year, no metastasis and a tumor diameter of less than 9 centimeters.

Adult↗