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At least 1,099 records · Page 61Linked to original sources
PubMed1989

Biodistribution of 131I-radiolabelled plasma low density lipoprotein in hyperlipidaemic vervet monkeys.

Low density lipoprotein (LDL) labelled with 131I has been administered to 6 Vervets 2 of which were high responders to an atherogenic Western diet in terms of plasma cholesterol, 2 were low responders and 2 were fed a high carbohydrate control diet. The ratio of hepatic to cardiac activity was recorded for up to 10 days after administration of the labelled LDL. Liver activity had a longer biological half life in the high-responders and this can be interpreted in terms of a variation of hepatic metabolism of LDL, with direct relevance to the human situation.

Animals↗
PubMed1989

Increased peripheral lymphocytes, lymphoid hepatitis and anaemia in African vervet monkeys seropositive to retroviruses.

Wild-caught African Vervet monkeys are commonly infected by Simian T-lymphotropic virus I (STLV1) and Simian immunodeficiency virus (SIV), yet the natural histories of these infections are largely unknown. Seropositivity was associated with increased total, T and atypical lymphocytes. In seropositive females there was mild, normocytic, normochromic anaemia. Lymphoid hepatitis was present in seven seropositive cases. African Vervets used in biomedical research, vaccine production and organ transplantation research are often infected by exogenous retroviruses which can be oncogenic and immunosuppressive in captive monkeys. Elimination of these infections may be possible by breeding Vervets in captivity.

Anemia↗
PubMed1985

Phenylacetic acid production in dominant and non-dominant vervet monkeys.

Free and conjugated plasma phenylacetic acid concentrations were significantly higher in dominant male vervet monkeys than in non-dominant males living in stable social groups. These findings may be connected with an earlier observation that plasma from aggressive human psychopaths contains higher concentrations of phenylacetic acid than non-aggressive controls; whether they reflect an increased production of phenylethylamine is still unknown.

Animals↗
PubMed1977

The effect of a proteolytic enzyem mixture (Orenzyme-Forte) on experimentally induced pulpitis.

A proteolytic enzyme mixture, Orenzyme-Forte, containing trypsin, chymotrypsin, and ribonuclease was used to treat experimentally induced pulpitis in the teeth of three monkeys. Assessment by means of the criteria of Stanley showed that the enzyme mixture induced better healing than a zinc oxide--eugenol dressing. When the two were used simultaneously, a synergistic effect was seen. We suggest that this enzyme mixture may be useful in clinical practice in the treatment of pulpitis.

Animals↗
PubMed1978

Histologic response of replanted teeth pretreated with acidulated sodium fluoride.

Central incisors in the vervet monkey were extracted, endodontically treated, and replanted into their original sockets after immersion in a 2 per cent acidulated sodium fluoride solution (pH 5.5) for 30 minutes. Histologic examination at 1, 2, 4, and 8 weeks postoperatively showed that by the second week resorption had taken place and that ankylosis, first seen by the fourth week, along both the buccal and palatal root surfaces, was well established by the eighth week. Under the conditions of the study, pretreatment of the tooth roots with 2 per cent acidulated sodium fluoride did not reduce root resorption and ankylosis.

Acids↗
PubMed1985

Isobutyl cyanoacrylate: a clinical and histologic comparison with sutures in closing mucosal incisions in monkeys.

Bilateral vertical incisions were made in the maxillary and mandibular labial mucosa of eight young green vervet monkeys. Incisions were closed with either interrupted 4-0 black silk sutures or by the application of isobutyl cyanoacrylate. Mucosal specimens containing the incisions were examined histologically and scored for degree of inflammation at 1, 3, 10, and 20 weeks. The results showed that cyanoacrylate and sutures did not produce similar inflammatory responses.

Animals↗
PubMed1982

Phrenic motoneurone activity in split-brainstem cats and monkeys.

A mid-line incision of the lower brainstem (from 2 mm caudal to 14 mm rostral to the obex) was performed in 14 cats and (from 2 mm caudal to 7 mm rostral to the obex) in three green monkeys and its effects on the respiratory activity of both phrenic nerves were studied under similar experimental conditions (halothane anaesthesia, artificial ventilation). Splitting the medulla in cats abolished the phrenic nerve activity under eupnoeic conditions, but hypercapnia or (with more rostral cuts) hypercapnia with hypoxia restored synchronous, rhythmic firing in both phrenic nerves. The response to splitting in eupnoeic monkeys was qualitatively different and consisted in a 'desynchronisation', i.e. independent firing of both phrenic nerves at different rhythms and patterns. It is concluded that cats and monkeys have basically different functional organisation of the respiratory controller.

Animals↗
PubMed1978

Ebola haemorrhagic fever: experimental infection of monkeys.

Experimental infection of rhesus and vervet monkeys with Ebola virus produced a uniformly fatal illness. The course of the disease resembled that found in man with weight loss, anorexia, fever, haemorrhages and skin rash being frequently seen. Viraemia was obvious within two days of infection and persisted until death which occurred between days five and eight. Virus was found in high concentrations in several organs but particularly in the liver, spleen, and lungs.

Animals↗