[Difficult colo-colonic or colo-rectal anastomoses: trans-mesenteric anastomoses and anastomoses with right colonic inversion].
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The principle enzymes in the metabolism of both the substituent groups and the nucleus of the bile acids and of cholesterol are reviewed, together with their possible relevence to the etiology of large bowel cancer. Since the incidence of the disease appears to be related to the bile acid concentration and the activity of the 7-dehydroxylase and the delta4-dehydrogenase enzymes, the study of bile acids with a 4,6-dien-3-one structure is strongly recommended.
Quantitative analysis of the lymphocyte infiltration at the periphery of colorectal carcinomata has revealed a statistically significant difference, p less than 0.001, in the distribution associated with Dukes B compared with Dukes C tumors of moderate differentiation.
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