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Local cost sharing in Bamako Initiative systems in Benin and Guinea: assuring the financial viability of primary health care.

The fourth in a series of five, this article presents and analyses data on cost recovery and community cost-sharing, two key aspects of the Bamako Initiative which have been implemented in Benin and Guinea since 1986. The data come from approximately 400 health centres and result from the six-monthly monitoring sessions conducted from 1989 to 1993. Community involvement in the financing of local operating costs in the two national scale programmes is also described. In Benin and Guinea, a user fee system generates the community financed revenue with the aim of covering local operating costs including drugs. Health worker salaries remain the responsibility of the government and donor funding covers vaccine and investment costs. Village health committees manage and control resources and revenue. The community is also involved in decision making, strategy definition and quality control. In Benin in 1993, community financing revenue amounted to about US$0.6 per capita per year and generally covered all local recurrent non salary costs except vaccines and left a surplus. Although total costs and revenues were slightly lower in Guinea for the same period, over-all user fee revenue (around US$0.3 per capita per year) covered local recurrent costs (not including salaries or vaccines). A comparison of costs and revenue between regions and individual health centres revealed important differences in cost recovery ratios. In Benin, some centres recovered more than twice the local costs targeted for community financing. Twenty-five per cent of centres in Guinea did not manage to cover their designated local recurrent costs. The longitudinal analysis showed that the level of cost recovery remained stable over time even as preventive care (and especially EPI) coverage rose significantly. To better understand the most important characteristics affecting cost recovery levels, best performing health centres in terms of cost-recovery levels in 1993 were compared to worst performing centres. This analysis showed that the size of the target population of the health centre is a key determinant of cost-recovery in both countries. In addition, in Guinea the utilization of curative care linked to geographical access and in Benin the average revenue per case linked to the number of deliveries proved to be additional factors of importance. In best performing centres, financial viability improved over time in both countries between 1990 and 1993. Finally, the implications of these conclusions for the planning of health centre revitalization in West Africa are discussed.

Benin↗

Management of locally advanced and disseminated breast cancer--chemotherapy.

Breast cancer is one of the most responsive of the common solid tumors when systemic therapy is indicated in the treatment of locally advanced or disseminated cancer. Many single agents have been useful in inducing remission in mammary carcinoma, but in recent years various drug combinations have been developed that appear more effective than individual drugs and in some instances with reduced toxicity levels. Adriamycin is the most interesting of the newer drugs and is the most effective single agent. Polychemotherapy of breast cancer was tried years ago, but remained for Cooper to arouse professional interest in multiple-drug therapy. Many modifications of this original five-drug regimens have been tried. One of the most widely used combinations is the CMF program, which includes cyclophosphamide, methotrexate, and 5-fluorouracil. The program that we have come to regard as our standard program in controlled clinical trials (CFP) employs cyclophosphamide, 5-fluorouracil, and prednisone. Toxicity with this program has been clinically acceptable, and in multiple comparative trials we have found no combination with greater therapeutic efficacy.

Alkylating Agents↗

'I got a letter...' a qualitative study of women's reasoning about attendance in a cervical cancer screening programme in urban Sweden.

OBJECTIVE: This explorative study aims at investigating how 'healthy' women describe and reason about participation in a cervical cancer screening programme in Sweden. The study is part of a multidisciplinary research project studying a population-based cervical cancer-screening programme from the perspective of different actors. SETTING AND METHODS: Data collection took place at three ante-natal health centres (ANHCs) in demographically diverse areas in the Stockholm region in spring 1995. Interviews were conducted and audiotaped with 66 'healthy' women at the ANHCs immediately before taking a Papanicolau test. Open questions such as 'Why have you come here today?' and 'What kind of test will you take?' were used to initiate the interview. Verbatim transcripts were analysed with a modified phenomenographical method to identify and describe qualitatively different ways of understanding cervical cancer screening. RESULTS: Four different ways of reasoning about cervical cancer screening are described, with only one similar to the biomedical rationale for screening with focus on attending for the test/results. Two types of reasoning refer to the invitation letter as a catalyst, with one emphasizing benefits in attendance and the second emphasizing hinders to attendance. A final way of reasoning focuses on the individual's own proactive role in prevention. Common themes are also identified. IMPLICATIONS: This study complements the research literature by providing a better knowledge base of the variations in reasoning among women attending screening, often seen as a homogenous group. It can contribute to better adapting the screening situation to the varied needs and expectations of the women who attend.

Adult↗

Social risk management options for medical care in Indonesia.

This paper investigates the extent to which price subsidies for medical care are a suitable instrument to reduce household's exposure to catastrophic financial risks associated with ill-health in Indonesia. Using the 1995 SUSENAS household survey, the observed distribution of user fees and health expenditures is used to derive a distribution of 'needed' medical expenditures. The trade-off between the tax burden and effectiveness in reducing the exposure to catastrophic risk is analyzed for two existing price regimes along with a number of hypothetical regimes. We find that the existing regimes significantly reduce the exposure to catastrophic shocks but do not eliminate them. Simulations suggest that further reductions could be achieved if a larger proportion of government subsidies were directed to inpatient care. Subsidizing outpatient treatment is a cost effective policy to reduce exposure to catastrophic risks only for the very poor.

Adult↗

Health insurance and treatment seeking behaviour: evidence from a low-income country.

This paper analyses the effect of being insured under the voluntary component of Vietnamese Health Insurance, on patterns of treatment seeking behaviour. A multinomial logit model is estimated using household survey data from three provinces in Vietnam. Decisions regarding both the type of provider sought and type of care received are analysed. Insurance status is treated as both exogenous and endogenous to account for potential selection bias. The results indicate that, overall, insured patients are more likely to use outpatient facilities, and public providers, an effect that is particularly strong at lower income levels.

Adult↗

Bowel continence for the child with a neurogenic bowel.

For more than 10 years, the Alfred I. duPont Institute's Spinal Dysfunction Clinic in Wilmington, DE, has helped families and their children with myelomeningocele and neurogenic bowels to establish workable, acceptable, physiologically sound bowel programs. The basic bowel management program at the Alfred I. duPont Institute is described here, as is a program by which a child with a neurogenic bowel can obtain continence. The program is based on the child's developmental level, physiological abilities, and any necessary pharmacologic intervention. The program has enabled approximately 75% of its child patients over age 5 with neurogenic bowel to be continent of stool.

Child↗

A probit analysis program for the personal computer.

Application software for economical and convenient calculation of median effective doses, confidence limits, potency ratios and slopes of quantal dose-response curves using a microcomputer is presented. The PASCAL language program is stored on diskette and it is compatible with many commercially available microcomputer systems. The program will simultaneously calculate the parameters for up to 20 different treatments and a total of 100 doses. Comparisons between the results of calculations of the LD50 of thiopental in mice using the PASCAL program, a modem-accessed commercially available probit analysis program and three, widely accepted manual calculation methods are made. The results of calculations of parallelism and the potency ratio between thiopental and phenobarbital-induced death in mice are shown.

Animals↗

Quantification of plasma and egg 4,4'-dinitrocarbanilide (DNC) residues for the efficient development of a nicarbazin-based contraceptive for pest waterfowl.

Urbanization and associated landscaping has increased the abundance of year-round habitat for waterfowl, resulting in vegetation damage, loss of recreational activities, air transportation mishaps and health hazards. As part of a research program to develop socially acceptable techniques for management of pest bird populations, we are evaluating nicarbazin as a contraceptive in pest and surrogate avian species. As reproductive studies with Canada Geese (Branta canadensis) are tedious due to the difficulty of conducting controlled field studies and/or breeding geese in captivity, we evaluated the effects of oral nicarbazin administration on the production and hatchability of chicken eggs. Blood plasma and egg DNC concentrations were correlated to contraceptive efficacy. Subsequent studies are being conducted with geese to determine the diet nicarbazin concentration required to produce the desired blood and plasma DNC concentrations. This approach permits the expeditious evaluation of formulations and dosing regimes by simply monitoring blood DNC concentrations in target species.

Animal Feed↗

The escalating cost and prevalence of alternative medicine.

BACKGROUND: The purpose of this study was to measure trends in the prevalence and cost of alternative medicines and alternative practitioner use in an Australian population and to obtain a profile of users and their beliefs. METHODS: In 2000, we repeated a 1993 representative population survey of persons ages 15 years or older living in South Australia, which provided 3,027 personal interviews. We assessed the rates of use, types of alternative medicine and therapists, costs, and beliefs of users and nonusers. Comparisons in usage patterns with the 1993 survey were also made. FINDINGS: In 2000, the overall use of at least one nonmedically prescribed alternative medicine (excluding calcium, iron, and prescribed vitamins) was 52.1% (CI +/- 1.8). Users were more likely to be female, be better educated, have a higher income, and be employed. Since 1993, females were using significantly more herbal medicines, ginseng, Chinese medicines, and aromatherapy oils. Many were self-prescribed. Among users, 57.2% (CI +/- 1.2) did not tell their doctor. In 2000, 23.3% of respondents had visited at least one alternative practitioner with increasing use of acupuncturists, reflexologists, aromatherapists, and herbal therapists. Most thought alternative medicines were safe but thought they were, or should be, subject to the same standards as prescribed medicines. Among respondents, 92.9% wished product information to be of standard and content similar to those supplied with pharmaceuticals. INTERPRETATION: Extrapolation of the costs to the Australian population gives an expenditure on alternative therapies in 2000 of $AUD2.3 billion and for the U.S. population an annual expenditure of $US34 billion. In Australia this represents a 120 and 62% increase in the cost of alternative medicines and therapists, respectively, since 1993. In 2000 expenditure on alternative therapies was nearly four times the public contribution to all pharmaceuticals. The public appears to have ambivalent standards for alternative therapies but wishes to be empowered with accurate information to facilitate self-prescription. The public health ramifications of an expanding alternative medicine industry are great.

Adult↗

Modeling cross-border care in the EU using a principal-agent framework.

Cross-border care is likely to become a major issue among EU countries because patients have the option of obtaining treatment abroad under Community Regulations 1408/71. This paper develops a model formalizing both the patient's decision to apply for cross-border care and the authorizing physician's decision to admit a patient to the program. The patient is assumed to maximize expected utility, which depends on the quality of care and the length of waiting in the home country and the host country, respectively. Not all patients qualifying for the EU program present themselves to the authorizing physician because of the transaction cost involved. The physician in her turn shapes effective demand for authorization through her rate of refusal, which constitutes information to potential applicants about the probability of obtaining treatment abroad. The authorizing physician thus acts as an agent serving two principals, her patient and her national government, trading off the perceived utility loss of patients who are rejected against her commitment to domestic health policy. The model may be used to explain existing patient flows between EU countries.

Catchment Area, Health↗

A graphical user interface to facilitate patient-specific drug dosing.

This paper describes the development of a graphical user-interface (GUI) designed to facilitate the process of generating patient-specific drug doses using bayesian modelling software. The graphical user interface was developed in Visual Basic (Microsoft, Inc.) and runs under the Windows 3.1 (Microsoft, Inc.) operating system. Patient demographic data are stored in a relational database (Access, Microsoft, Inc.). The GUI and the database communicate via dynamic data exchange links. The largely object-oriented nature of the language allowed us to change the entire look and feel of the system with a few simple changes to the underlying code. Use of the relational database to store patient demographic information allows greater flexibility in searching for and displaying patient specific information. The GUI reduces the time required to enter data. The prototype has allowed us to experiment with different presentation methods, greatly improving the clinical acceptance of the dosing programs.

Computer Simulation↗

Influence of brisk walking on the broadband ultrasonic attenuation of the calcaneus in previously sedentary women aged 30-61 years.

The amount and type of exercise needed to maintain or increase bone density in women is unclear. The purpose of the present study was to examine the influence of brisk walking on broadband ultrasonic attenuation (BUA) values for the calcaneus in formerly sedentary women aged 30-61 years (mean 44). Twenty-five women followed the program of brisk walking for 1 year and 15 acted as controls. The walkers completed an average (SEM) of 159 (46) minutes/week of brisk walking at a speed of 1.72 (0.05) meters/second, i.e., about 16-18 km/week. Broadband ultrasonic attenuation was determined at baseline and after 1 year. Analysis of variance showed that values were increased (P less than 0.05) for the walkers relative to controls [walkers 103.3 (4.9) versus 116.1 (3.8) dB/MHz; controls 103.6 (5.5) versus 99.6 (5.4) dB/MHz]. We conclude that, in formerly sedentary women, a modest program of a widely acceptable form of exercise, brisk walking, can provoke an increase in this sensitive index of bone condition.

Adult↗

Understanding stroke recovery and rehabilitation: current and emerging approaches.

Although stroke is the third leading cause of death in the United States, it is the significant disability among survivors that has the greatest impact on healthcare and society. It is currently accepted that comprehensive rehabilitation programs improve outcome following stroke. We are now trying to discern which specific therapeutic approaches work and which do not. Years of animal research have resulted in a better understanding of what occurs in the brain following stroke and how the brain may reorganize in response to treatment. Repetitive use of the involved extremities appears key to optimal behavioral recovery and optimal brain reorganization. The advent of technology such as functional magnetic resonance imaging and transcortical magnetic stimulation has allowed the study of brain reorganization following stroke and rehabilitation in humans. Certain drugs also appear to influence neuroplasticity after stroke. Timing of therapy and drug delivery appears crucial; the optimal "critical period" has not yet been clearly identified. New approaches are slow to reach widespread adoption. Neural transplantation combined with repetitive training approaches produces behavioral recovery in animals and offers hope for the future.

Animals↗

Self-referral and self-payment in Danish primary care.

This study aims at characterizing the group of people who want to have the right to consult any general practitioner or practising specialist without referral on condition of part self-payment, as opposed to the group of people who choose to be registered with a general practice that offers free services but controls further access to the health care system. All adults or a 10% sample of those listed in nationwide Danish registers were examined cross-sectionally for social and demographic factors and utilization of primary and secondary health care. A minority, which totals 3% of the population, chose free choice of doctor and part self-payment. On average, this group is older and has a higher income. Its mortality and its utilization of general practice and hospital services are lower, and its use of practising specialists is higher, than the majority. Among the persons who chose free choice and self-payment, the pattern of utilization is more likely to be due to a wish for free choice and for specialized medical care than to high morbidity. Dissatisfaction caused by restrictions on self-referral to specialists can be met by offering an option of a parallel system of free choice of doctor on condition of part self-payment.

Age Distribution↗

Participation: myths, realities and prognosis.

The prospects for increased participatory approaches in health arenas has to recognise not only the encouraging developments (e.g. the "rights" legislation, global health program approaches, social action acceptability, growth in community advocacy skills, freedom of information legislation) but also the persistence of some long-standing impediments (e.g. entenched medical dominance, antagonistic bureaucratic cultures, a centralist supremacy, an intractable political economy of health, inhibitory professional paradigms). There are wide variations between societies in the way these developments and impediments are traded off or balanced, ultimately depending upon how such issues as the sharing of knowledge and skills, information access, challenges to power and practics paradigms are being recognised and resolved in specific contexts.

Australia↗