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Interictal acute psychoses in temporal lobe epilepsy during withdrawal of anticonvulsant therapy.

Acute interictal psychotic attacks during withdrawal of medication are described in two patients with temporal lobe epilepsy submitted to depth EEG study with a view to surgical treatment. The patients were on chronic treatment with clonazepam associated in one with phenobarbitone and in the other with phenobarbitone plus carbamazepine. Our observations suggest that the acute withdrawal of clonazepam, the plasma levels of which were monitored may play a part in producing psychotic attacks characterised by dysphoric manifestations, irritability, aggressiveness, anxiety, and hallucinations. These symptoms could be interpreted as a withdrawal syndrome.

Adult↗

Mean age, sex ratio and psychopathology in alcohol psychoses.

In a retrospective study the case histories of 154 patients with acute alcohol psychosis were examined. The obvious diagnostic criteria in the doctor's differential diagnosis between alcohol withdrawal delirium and alcohol hallucinosis was clouding of sensorium and disorientation. 103 patients were diagnosed as having alcohol withdrawal delirium, 51 patients alcohol hallucinosis. Mean age and sex ratio were the same in both groups. Further psychopathological symptoms in both groups supporting differential diagnosis are discussed.

Adult↗