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Results for “PLASMA SUBSTITUTES”

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At least 1,081 records · Page 60Linked to original sources
PubMed1980

Prevention of allergoid (cutaneous anaphylactoid) reactions to polygeline (Haemaccel) in orthopaedic patients by premedication with H1- and H2-receptor antagonists.

"Purified" polygeline (Haemaccel) was examined for its anaphylactoid and allergoid reactions in a controlled clinical trial on a homogenous sample of orthopaedic patients. In two test groups histamine H1- and H2-receptor antagonists were applied, in the control group saline as a placebo premedication. Unexpectedly no anaphylactoid reaction associated with histamine release greater than or equal to 1 ng/ml plasma occurred in the trial. Clinically unimportant allergoid reactions restricted to the skin occurred with a lower frequency (18%) than observed in previous trials. The specific premedication was highly effective in preventing these reactions in the two test groups (p less than 0.0005). Due to the apparent improvement of the product a general premedication with histamine H1- and H2-receptor antagonist seems not to be necessary before polygeline is administered to patients. For reasons of safety, however, it seems to be indicated in patients at risk, such as those with carcinoma, a proven allergic diathesis and in those who have already suffered from an incident to plasma substitutes.

Anaphylaxis↗
PubMed1981

[Changes in electrolyte homeostasis in acute loading of the right heart].

The authors carried out experimental studies on electrolyte homeostatis of healty cats and of cats with experimental stenosis of the lung artery after venous infusion of the dextran plasma substitute Reoisodex. There was a statistically significant reduction only of the level of ionized calcium under the influence of the infusion. The authors established an increase of the level of inorganic phosphorus and of the serum bicarbonates in animals with experimental stenosis of the lung artery.

Animals↗
PubMed1981

Comparison on the pulmonary effects of rapid infusion of a crystalloid and a colloid solution.

The cardio-pulmonary effects of a rapid infusion of a crystalloid (Ringer's lactate) and a colloid solution (Dextran 40) were compared in healthy dogs. The colloid solution produced a long lasting volume expansion and hemodilution. The improved circulation in this group was reflected in an increased cardiac output and arterial blood pressure. The ventilation/perfusion ratios were reduced and the pulmonary vascular resistance was significantly lower in the colloid group in comparison both to the crystalloid group as well as to the control animals. The total oxygen consumption increased slightly in the colloid group but decreased in the crystalloid group. The postmortem extravascular lung water content did not differ in the groups.

Animals↗
PubMed1984

Crystalloid versus colloid resuscitation in experimental hemorrhagic pancreatitis.

In a canine model of acute hemorrhagic pancreatitis, crystalloid resuscitation with a balanced salt solution adequately restored plasma volume, supported tissue perfusion and prevented excessive hemodilution without detrimental effects on pulmonary pressures or oxygenation. No advantages in using colloid resuscitation were apparent in our study.

Acute Disease↗
PubMedDate not supplied

[Method of electrochemical studies on the effect of corrosive media on the corrosion resistance of medical instruments].

Considerations are given to some methodical problems, and corrosion performance of stainless steels 30 X 13 and 03X11H10 M2T2 used for production of medical instruments is studied by using the method of anode polarization curves. The treatment in hydrogen peroxide is shown to exert a distinct passivating effect on surfaces of the steels under study. Among the bioactive media the plasma substituting agent gelatinol is the most aggressive. When studying the corrosion resistance of metals by potentiostatic methods the physiological solution imitating the blood is proposed to be used as an operating medium.

Corrosion↗