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A congenital intraspinal gastroenterogenous cyst in diastematomyelia.

A female neonate, with neurological signs and leucocytosis in sterile spinal fluid, was found to have anomalies of the upper thoracic vertebral bodies with a bony spur indicating diastematomyelia. The spur was removed, but symptoms recurred. Necropsy at the age of 5 months revealed an intraspinal gastroenterogenous cyst containing a perforated peptic ulcer. Analysis of eight previous reports of intraspinal enterogenous cysts, shows that, like prevertebral enterogenous cysts, they are frequently combined with defects in the vertebral bodies. This association suggests development from an embryonic ectoendodermal adhesion. Vertebral body defects are a significant pointer to the diagnosis and should not be overlooked, as curative resection is sometimes possible.

Cysts↗

Serum trypsin levels in acute pancreatic and non-pancreatic abdominal conditions.

Serum trypsin levels have been estimated by radioimmunoassay in 26 healthy controls (248 +/- 94.9 micrograms/l; mean +/- s.d.), 12 patients with chronic renal failure (1100 +/- 584 micrograms/l), 34 with acute pancreatitis (1399 +/- 618 micrograms/l) and 23 with acute non-pancreatic abdominal conditions. Mean serum trypsin in acute pancreatitis and in chronic renal failure was significantly higher than in control group (P less than 0.001). Serum trypsin levels were well above the upper limit of normality in all patients with acute pancreatitis and in all but one with chronic renal failure. Serum trypsin was markedly raised in one patient with a traumatic haemoperitoneum and in one of the 11 with peptic ulcer perforation, and moderately raised in 3 of the 6 with acute cholecystitis. Determination of serum trypsin seems to be a specific test for acute pancreatitis, provided renal failure has been excluded. However, the authors suggest it should be prospectively measured in a larger series of acute non-pancreatic abdominal conditions.

Acute Disease↗

Changing pattern of clinical features and prognosis in systemic lupus erythematosus.

The changing pattern of clinical features of and prognosis for 206 patients with SLE were studied. SLE patients with Raynaud's phenomenon and minimal change and focal proliferative glomerulonephritis observed by means of renal biopsy tended to increase in C (1972--76) group compared with A (1955--68) and B (1969--71) groups. SLE patients with lupus nephritis and central nervous system lupus treated with large doses of steroids or combined therapy of steroids and immunosuppressive agents also increased in the order C, B, and A group. The prognosis for group C patients was better than that for A and B group patients. However, there appeared to be an increasing incidence of complications unrelated to SLE, namely infection and perforated peptic ulcer.

Adolescent↗

Epidemiology of non-trauma surgical deaths.

BACKGROUND AND OBJECTIVES: It is established that 70 % of morbidity and 75 % of mortality in the surgical accident and emergency (A and E) are due to trauma. However, non-trauma deaths still are an important entity requiring a specific study to highlight their pattern, and institute improvement strategies to lower death rates. METHODOLOGY: A retrospective analysis among non-trauma surgical deaths that occurred in the A and E Department of the University of Ilorin Teaching Hospital, Ilorin, Nigeria, over 24 months was done. Data collected included age, sex, interval between onset of illness and presentation, clinical features, occurrence of prior hospital visit, investigations done, cadre of surgeons that reviewed the patients and the interventions done as part of treatment before death. RESULTS: 4164 patients visited the A and E, 2916 (70%) were trauma, 1251 (30%) were non-trauma conditions. There were 171 deaths, 129 (75.4%) were trauma deaths while 42 (24.6%) were non-trauma deaths. Thirty (71.4%) of the 42 had complete information for analysis. Age range was 2-95 years (mean 42.7 +/- 21.8 years) comprising 18 males and 12 females. Patients with generalized peritonitis were in the majority 8 (26.7 %) comprising typhoid perforation 4, ruptured appendix 2 and perforated peptic ulcer 2. Terminal malignancies followed closely with 6 deaths (20.0%), 3 from urological causes (2 prostatic and 1 bladder cancer), acute gastrointestinal bleeding 3 (10%), intestinal obstruction 1 (3.3 %) and others. Nineteen patients (63.3%) had visited a previous hospital where they had spent <48 hrs (4 patients), 48hrs -1 week (4 patients) and >1 week (2 patients), undocumented (9 patients). Less than 40% of the patients were able to do the requested investigations (electrolytes, X-rays and ultrasound) or got the desired interventions (blood and antibiotics) CONCLUSION: Non-trauma deaths account for a quarter of the deaths in the A and E, generalised peritonitis and advanced malignancies were the main conditions responsible and characterized by late presentation, having spent a considerable time in a previous private hospitals.

Adolescent↗

[Reasons for reoperation after laparoscopic cholecystectomy].

AIMS: Analysis of the reasons for reoperation after laparoscopic cholecystectomy. METHODS AND PATIENTS: Retrospective-prospective analyses of the first 250 patients who undergone laparoscopic cholecystectomy. In 86% cases indication for operation was chronic calculosis of gallbladder. RESULTS: Reoperation was performed at 6 patients (2.4%). The reasons of reoperation were: haematoma of gallbladder's loge (1), biliary fistulas (1), biliary peritonitis (1), abdominal abscesses (2), and perforated peptic ulcer (1). At 2 patients with intraabdominal abscesses, it was solved by laparoscopic drainage. The other complications were solved with laparotomy, also. We did not have lethal cases after reoperation. CONCLUSION: Rate of postoperative complications was 2.4%, and all of them required reoperation. Our results are similar with results of the other authors.

Cholecystectomy, Laparoscopic↗

Ectopic pancreas with gastric outlet obstruction: report of two cases and literature review.

Ectopic pancreas is a rare entity and is usually an incidental finding in clinical practice. Most patients with an ectopic pancreas are asymptomatic, and if present, symptoms are non-specific according to the site of the lesion and different complications encountered. The most-common site is the stomach, accounting for 25%-38.2% of all patients. An asymptomatic ectopic pancreas is usually of no clinical importance, and there is no surgical indication in such a situation. However if there are complications caused by an ectopic pancreas, a variety of actions becomes necessary. We report 2 cases of ectopic pancreas with gastric outlet obstruction. The first case was a 41-year-old man who suffered from epigastric fullness and dyspepsia for 3 years. Endoscopic examination revealed a submucosal tumor measuring 2.5 cm in diameter in the prepyloric area. The second case was a 53-year-old man, who initially underwent a craniotomy to remove a pituitary adenoma, and laparotomy and duodenorrhaphy due to a perforated peptic ulcer. The postoperative course was not uneventful, and an upper gastrointestinal series showed a 2-cm intramural mass with a mucosal ulcer at the distal antrum. Both cases had symptoms and signs of gastric outlet obstruction, and both cases accepted subtotal gastrectomy with Billroth II anastomosis. A review of the literature revealed few cases of ectopic pancreas with gastric outlet obstruction. An ectopic pancreas must be considered in the differential diagnosis of gastric outlet obstruction.

Adult↗

[Laparoscopic surgery for gastroduodenal disease].

Since 1990, laparoscopic surgery for gastrointestinal disease has been accepted worldwide because it is minimally invasive, associated with less pain, and results in early recovery. For the surgical management of gastroesophageal reflux and perforated peptic ulcer, laparoscopic procedures are recognized as the standard. Laparoscopic gastrectomies for cancer have developed since 1991. Laparoscopic wedge resection and intragastric mucosal resection are performed for the treatment of early gastric cancer without the risk of lymph node metastasis. For early gastric cancer with the risk of perigastric lymph node metastasis, laparoscopy-assisted Billroth-I gastrectomy with D1 lymph node dissection has been successfully performed. Thus, laparoscopic approaches play an important role in the management of gastroduodenal disease.

Duodenal Diseases↗

Ulcer perforans.

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Humans↗