Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Multiphasic Screening”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 1,081 records · Page 60Linked to original sources
PubMed1980

Optimization of mobile multiphasic health testing.

Increasing governmental requirements are now forcing the occupational physician to examine automated health testing systems for employee health surveillance. Many companies have chosen to use mobile systems. The array of possibilities is bewildering and providers of such services vary widely. This article discusses the advantages and disadvantages of mobile health testing and also provides a checklist which can be used to assure optimization of such a program.

Female↗
PubMed1980

Nutrition in the Multiple Risk Factor Intervention Trial (MRFIT).

The Multiple Risk Factor Intervention Trial (MRFIT) is a clinical trial to determine whether primary prevention of coronary heart disease (CHD) is achievable. The main objective is to learn whether a special intervention program for men at increased risk of death from CHD can result in a significant reduction in mortality from this disease. For this investigation, 12,866 men, ages thirty-five to fifty-seven years, have been enrolled, after having been identified at increased risk because of a combination of risk factors: Elevated serum cholesterol, elevated diastolic blood pressure, and cigarette smoking. MRFIT provides an excellent opportunity for nutritionists to work closely with physicians, behavioral scientists, nurses, and other scientists in a program to change food habits, reduce blood pressure, and achieve cessation of smoking.

Cholesterol↗
PubMed1980

Assessing dietary adherence in the Multiple Risk Factor Intervention Trial (MRFIT). I. Use of a dietary monitoring tool.

Participants in the Multiple Risk Factor Intervention Trial (MRFIT) were taught not only how to modify the fat content of their diets but also how to assess their success in doing so. To simplify the process, a food scoring system was developed in which positive points are assigned to high-saturated-fat and high-cholesterol foods and negative points to foods and high-polyunsaturated-fat and low-cholesterol content. Using special forms supplied by MRFIT nutrition counselors, participants were able to self-monitor their dietary regimens. The method is described and forms are illustrated.

Coronary Disease↗
PubMed1980

Assessing dietary adherence in the Multiple Risk Factor Intervention Trial (MRFIT). II. Food record rating as an indicator of compliance.

The reliability of the food record rating (FRR) sytem devised for assessing nutritional compliance by participants of MRFIT was statistically validated. Two nutritionists in each of four clinical MRFIT centers each rated thirty records drawn from a pool of 120 records from twenty centers. The eight raters working independently in four cities were able to duplicate FRR scores 86 per cent of the time. The FRR provides a systematic, rapid measure of progress in food-habit change which would be applicable to other preventive nutrition programs

Coronary Disease↗
PubMed1980

Nutrition intervention strategies in the Multiple Risk Factor Intervention Trial (MRFIT).

The Multiple Risk Factor Intervention Trial (MRFIT) simultaneously intervenes on three major risk factors for coronary heart disease: Hypercholesteremia, hypertension, and cigarette smoking. It was, therefore, essential to develop intervention strategies which would be appropriate across all modalities. The initial methodology combines the transfer of basic information, the use of small groups of participants and their homemakers to facilitate changes in life style, and the use of the principles of behavioral change and maintenance theory to encourage long-term success in adapting and maintaining new habits over a life time.

Behavior Therapy↗
PubMed1995

[Histopathological assessment of renal biopsy specimens of subjects with urine abnormality].

Between April 1985 and April 1992, 25,672 men (age 47 +/- 9 years, mean +/- SD) and 9,791 women (48 +/- 9 years) underwent mass urinalysis in the Center for Adult Complete Physical Examination in our hospital. The results revealed proteinuria in 6.3% of the men and 4.4% of the women and hematuria in 17.4% of the men and 37.8% of the women. Thirty-five subjects with asymptomatic persistent proteinuria and/or hematuria identified as a result of follow-up testing by the nephrologists at our hospital underwent renal biopsy. All of the biopsy specimens obtained were examined by light microscopy, fluorescence microscopy and electron microscopy. Histopathological findings in the biopsy specimens from these 35 subjects were as follows: One case (3%) of chronic pyelonephritis, 11 cases (31%) of IgA nephropathy, 4 cases (11%) of IgA nephropathy (severe type), 5 cases (14%) of membranous nephropathy, 4 cases (11%) of thin basement membrane disease (TMD), 7 cases (28%) of benign nephrosclerosis and 3 cases (9%) of minor glomerular abnormality. Light microscopy, fluorescence microscopy and electron microscopy for histopathological assessment of renal specimens, especially for the diagnosis of TDM, which was not uncommon, were indispensable tools in our study. Moreover, it is essential for proteinuria and hematuria to be tested simultaneously using the same standard method in all the urine specimens collected.

Adult↗
PubMed1995

[An abnormal hemoglobin which was found by chance at a health checkup].

A 68-year-old female visited our hospital because of low hemoglobin A1c content, which was found by chance at a health checkup. She did not have any symptom or sign except hypertension and low HbA1c. To determine the reason why HbA1c was so low in usual laboratory test, we carried out isoelectrofocusing (IEF) of the hemolysate, Hb instability test, and detection and isolation of the abnormal globin chain by urea CM-cellulose column chromatography. The abnormal beta-globin chain was digested with TPCK-trypsin, and the tryptic peptides were separated by HPLC on a reversed phase column. Finally the determination of amino acid composition and amino acid sequence of the abnormal peptide were performed. The Hb variant was identified as Hb Riyadh (beta 120Lys-->Asn). The detection and analysis of abnormal hemoglobin will be expected to increase in accordance with the increased opportunity of public health checkup.

Aged↗
PubMed1993

Exposure to engine exhaust and risk of subsequent cancer.

We evaluated the relation between occupational exposure to engine exhaust fumes and cancer risk among members of a large prepaid health plan who reported on exposure during a routine health examination (n = 160,230). Exposure in the past year was associated with an elevated risk of cancer of the thyroid (relative risk (RR) = 1.99; 95% confidence interval (CI), 1.01-3.92), female breast (RR = 1.53; CI, 1.00-2.33), nonbrain nervous system (RR = 2.26; CI, 1.09-4.67), and lip/tongue (RR = 1.82; CI, 1.09-3.04), and a decreased risk of melanoma (RR = 0.50; CI, 0.27-0.90). However, another measure of exposure that included both exposure prior to 1 year and exposure in the past year was associated only with cancer of the lip/tongue (RR = 1.82; CI, 1.02-3.32). No association was observed for lung, bladder, or larynx cancer or multiple myeloma. Analyses limited to men, or stratified by time since health examination, did not distinguish other effects. Self-reported occupational exposure to engine exhaust fumes was not convincingly associated with most cancers in this cohort.

Adolescent↗
PubMed1994

[Aging changes of cerebral high intensity areas on T2-weighted MRI--a study in medical checkup patients].

To determine normal aging process of the brain, cerebral T2-weighted MRI was evaluated in 400 healthy individuals who visited our hospital for routine medical checkups. The results are summarized as follows. 1) High intensity areas (measuring 2 mm x 2 mm or more) were observed most frequently in the cerebral white matter including the corona radiata (CR). The incidence of these areas increased linearly with age, and approached about 50% in the patients of the seventh decade. 2) High intensity areas in the basal ganglia (BG) were the second commonest. High intensity areas were rarely seen in the thalamus (TH) and pontine base (PO). 3) High intensity areas were confined to the CR (66.9%) in the majority of the cases, while there were few cases having these areas restricted to the BG, TH and PO; that is, most of them were accompanied by additional high intensity areas in the CR. 4) Periventricular hyperintensity areas increased in size with age, and were prominent in those who had multiple or large high intensity areas in the CR, or those who had signal hyperintensity in the BG, TH or PO.

Adolescent↗
PubMedDate not supplied

Automated health testing in a medical group practice. Effects on physician behavior and economic influences.

An automated health testing (AHT) laboratory was introduced into a large medical group practice in January 1970. The impact of AHT was studied by means of a matrix of before and after its introduction and the physicians with high and low volumes of referrals to this service. An epidemiologic data-gathering approach was used to obtain information with minimal interference with normal clinic operation during a 3-year period. Data were obtained from the business office, appointment rosters, AHT laboratory results, and clinic records. AHT was accepted and used more frequently by the general and family practice physicians and internists than by the other physicians in the group practice. After AHT was introduced, the general physicians saw fewer patients but held longer visits, performed more procedures, and ordered fewer tests. On the other hand, the internists saw more patients but held shorter visits, performed more periodic reexaminations, and ordered fewer tests. The study findings indicate that in the short term AHT does not appear to reduce the cost of medical care. However, patients benefited from followup of AHT results; often, this followup resulted in significant newly diagnosed diseases or conditions, treatment, and sometimes surgery.

Adult↗