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At least 1,081 records · Page 60Linked to original sources
PubMed1995

[Degenerative colorectal polyps].

In 23 patients with malignant colorectal polyps we reviewed the frequency of recurrence. In the group without subsequent local resection, 8 of 11 patients were without recurrent tumour after 2.7 (0.8-4.1) years, in the group with subsequent local or conventional colon resection, 10 of 12 patients after 5.3 (0.8-9.0) years. None of the patients showed any evidence of residual tumour or lymph node metastasis. All recurrent tumours (2 x carcinoma, 3 x benign polyps) could be resected curatively. There was no difference in recurrence in both groups. For safe histopathological examination of malignant colorectal polypi in respect of depth of invasion, free resection margins and lymphatic vessel invasion, intraoperative fixation and marking must be performed, since local recurrence was seen after more than 5 years, long-term follow up is necessary.

Adult↗
PubMed1993

[Endoscopic resection of 49 polyps of the colon and rectum larger than 2 cm].

The management of rectal and colonic polyps has changed since the advent of endoscopic polypectomy, that interrupts the adenoma-carcinoma sequence. We assessed the effectiveness, limitations, morbidity and mortality of endoscopic polypectomy in 49 polyps larger than 2 cm in diameter. Polypectomy was successful in 94% of polyps, which were predominantly located in left colon (92%) and were pedunculated (87%). A malignant component was found in 28.3% of polyps, that was observed with higher frequency in larger and sessile polyps and in male patients. There was no mortality and scarce morbidity related to the procedure. It is concluded that polypectomy is a low risk procedure that can be frequently performed in ambulatory patients and that endoscopists must suspect malignancy in polyps larger than 2 cm in diameter.

Adolescent↗
PubMed1995

[Incidence of malignancy in millimetric polyps].

This paper is based on the analysis of 178 polyps of 5 mm or less (polyps we have termed "millimetric") studied in the Endoscopy Department of "La Paz" Hospital, Madrid, during 1993. All polyps fulfilling these characteristics detected during this period are included. The 178 polyps represent 43.4% of all polyps (N = 410) found on colonoscopy in this department in this period. The variables considered in the study protocol include age, sex, localization, morphology and histological examination, with particular attention to high risk histological lesions such as signs of possible malignancy.; we also performed a comparative study between the results obtained from the 178 millimetric polyps (Group I) and the 232 polyps greater than 5 mm (Group II) obtained during the same period. The endoscopic technique for the resection of the polyps was evaluated together with its possible complications. Although there were no significant differences found in respect to age, sex and location, there were morphological differences with a greater number of pediculated or semi-pediculated polyps in Group I whilst there were more sessile polyps in Group II. Adenomatous polyps were the most frequent (84%) in both groups. There was a greater incidence of signs of possible early malignant changes in Group II polyps (10) than in Group I (3.3%). The conclusions which may be drawn from our study are that it is clinically advisable to excise all polyps of 5 mm or less as the frequency of high risk histological changes is not negligible (3.3%), and excision is not problematic as the technique is easy and there have been no complications in our series.

Aged↗
PubMed1996

[Secondary lymphomatous polyposis of the gastrointestinal tract in patients with nodal lymphomas].

Multiplex lymphomatous polyposis is an uncommon disease characterized by polypoid accumulations of malignant lymphoid cells within the submucosa of long segments of the gastrointestinal tract. Primary gastrointestinal form of disease is referred as an extranodal variant of the entity knows as mantle zone lymphoma. Rarely, this typical lesion may appear as a secondary involvement of the alimentary tract in patients with primary nodal lymphomas. In present article, the clinical, histological features of our two cases of primary nodal lymphoma presenting with gastrointestinal symptoms and secondary involvement of the bowels are discussed. The nodal lymphomas of these patients were classified as a mantle zone and a follicle center cell origin lymphoma. The development of gastrointestinal symptoms occurred 29 and 41 months after the diagnosis. Our cases suggest that lymphomatous polyposis can manifest itself secondarily in patients with nodal lymphomas of not only the mantle cell type. The polypoid lesion might be mediated by lymphocyte homing receptors and the pattern of proliferation can be produced by more than one phenotypically different lymphoma.

Adult↗
PubMed1996

Screening programs in the population at large and in high-risk groups.

Existing guidelines for colorectal cancer screening in standard risk patients are reviewed, as well as the data on which they are based. A family history of colorectal cancer or significant adenoma increases the risk above that of standard risk individuals. Risk assessment and surveillance in higher risk individuals are discussed.

Adenomatous Polyps↗
PubMed2002

[Colorectal polyps].

The polyp is a focal mass that projects from the wall into the lumen. The term polyp is appropriate for gross, radiologic, and endoscopic usage and should be further modified to indicate topographic site, size, number and shape. Strictly spoken, a polyp consists of a head and a stalk, but also the lesions without a clear stalk, but still protruding into the lumen, are called (sessile) polyps. In this view, "polyp" means any lesion, which is circumscribed and raised above normal surrounding mucous membrane so that it is visible to the naked eye. Clinicians sometimes even use "polyp" to refer to any tumor detected in the large intestine. The term polyp does not hold any information about the pathological nature of the lesions. Some polyps (benign, non-neoplastic polyps) do not have an increased potential for becoming malignant, while other polyps (adenomas, neoplastic polyps) are precancerous, which may progress to malignant lesions (carcinomas). Thus polyps must be biopsied or resected to determine their histological type and establish a complete diagnosis.

Colonic Neoplasms↗
PubMed1981

[Villous neoplasms of the distal section of the large intestine].

Villiferous tumors and polyps are known to be precancer with high (46%) index of malignization. The authors have performed 131 operations for local ablation of tumors and polyps by electrocoagulation through a rectoscope, transanal dissection, procto- and colotomy. The authors make a conclusion that local ablation of villiferous newformations is an adequate method of their operative treatment. Continuous follow-up is recommended after such operations.

Electrocoagulation↗
PubMed1984

[Surgical tactics in small polyps in patients with polyposis of the large intestine].

Experience with the treatment of patients with multiple polyps of the colon is analyzed. They had large polyps and polyps with the diameter not more than 0,5 cm. The findings of morphological examination of such polyps and results of the dispensary observation of patients with non-ablated small polyps are described. A conclusion is made of the expediency of more active surgical tactics in relation to polyps less than 0,5 cm in diameter in this group of patients.

Adenoma↗