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The elderly: health status benefits and recovery of function one year after coronary artery bypass surgery.

OBJECTIVES: The purpose of this study was to describe the health status (symptoms, function, and quality of life) changes of elderly patients undergoing coronary artery bypass grafting (CABG) and compare these to younger patients. BACKGROUND: Despite increasing use of CABG in the elderly, few data exist about elderly patients' health status benefits from CABG. METHODS: A total of 690 consecutive patients (n = 156, >75 years of age; n = 534, <or=75 years of age) from a single center were administered the Seattle Angina Questionnaire (SAQ) at baseline and at one year. The first 224 patients were also given monthly questionnaires for six months after CABG. RESULTS: Although peri-operative mortality was similar (2.6% vs. 2.2%, p = NS), one-year mortality was greater in older patients (11.5% vs. 5.4%, p = 0.008). Among survivors, similar health status benefits were observed one year after surgery (SAQ change scores for Physical Function 21.5 +/- 27.0 vs. 19.7 +/- 27.0, p = 0.67; Angina Frequency 30.1 +/- 25.7 vs. 24.6 +/- 25.6, p = 0.07; and Quality of Life 37.7 +/- 21.8 vs. 33.6 +/- 25.2, p = 0.16). In 224 patients assessed monthly, elderly patients' physical function scores were significantly lower than the younger group until one year. The age-time interaction term was significant (p = 0.003), confirming a slower recovery of physical function. In contrast, angina relief and quality of life improvement did not differ by age. CONCLUSIONS: Despite a slower rate of physical recovery, older patients derived similar health status benefits from CABG compared with younger patients. These data should assist physicians in counseling elderly patients and suggest that age alone should not be a deterrent for recommending bypass surgery.

Age Factors↗

Comparing the health status of VA and non-VA ambulatory patients: the veterans' health and medical outcomes studies.

The purpose of this study was to compare health status and disease profiles of ambulatory patients in specific Veterans Administration (VA) and civilian healthcare settings. A random sample of 2425 male veterans seeking care at 4 Boston-area VA outpatient clinics, who took part in the Veterans Health Study (VHS) in 1993-1995, were compared to 1318 male patients seeking civilian outpatient care in 3 major metropolitan areas covered in the Medical Outcomes Study (MOS) in 1986. The MOS sampled patients who had 1 of 5 conditions--hypertension, noninsulin-dependent diabetes, recent myocardial infarction, congestive heart failure, or depression. These 2 samples were age adjusted and compared in terms of the SF-36 Health Status/Quality of Life measures, and a list of 100 clinical variables (diagnostic, symptom, and medical event reports) collected with comparable instruments by a trained clinical observer. Individual odds ratios (VHS to MOS) were calculated for each measure and clinical variables. SF-36 measures of patient health in the VHS were lower than those in the MOS by more than one half of a standard deviation (SD) on 4 of 8 scales, by more than one quarter of a SD on the other 4, by 58% of a SD on the physical health summary scale, and by 37% of a SD on the mental health summary scale (P < .0001 in all cases). The median odds ratio was 2.2 among the SF-36 scales and 1.9 among clinical variables. Outpatients in the 4 VA clinics had more than twice the illness burden than did patients in the MOS. Current economic condition and service-connected disability explain most, if not all, of the differences. The differences were clinically and socially meaningful and would be consistent with substantially higher expected healthcare use.

Ambulatory Care Facilities↗

The impact of increasing patient prescription drug cost sharing on therapeutic classes of drugs received and on the health status of elderly HMO members.

OBJECTIVE: To assess the impact of increased prescription drug copayments on the therapeutic classes of drugs received and health status of the elderly. HYPOTHESES TESTED: Increased prescription drug copayments will reduce the relative exposure to, annual days use of, and prescription drug costs for drugs used in self-limiting conditions, but will not affect drugs used in progressive chronic conditions and will not reduce health status. STUDY DESIGN: Each year over a three-year period, one or the other of two well-insured Medicare risk groups in an HMO setting had their copayments per dispensing increased. Sample sizes ranged from 6,704 to 7,962. DATA SOURCES/DATA COLLECTION: Automated administrative data systems of the HMO were used to determine HMO eligibility, prescription drug utilization, and health status. ANALYSIS DESIGN: Analysis of variance or covariance was employed to measure change in dependent variables. FINDINGS: Relative exposure, annual days of use, and prescription drug costs for drugs used in self-limiting conditions and in progressive chronic conditions were not affected in a consistent manner across years by increases in prescription drug copayment. Health status may have been adversely affected. Larger increases in copayments appeared to generate more changes. CONCLUSIONS: Small changes in copayments did not appear to substantially affect outcomes. Large changes in copayments need further examination.

Aged↗

The relationship of chronic sputum expectoration to physiologic, radiologic, and health status characteristics in alpha(1)-antitrypsin deficiency (PiZ).

STUDY OBJECTIVES: First, to determine the relationships among chronic sputum expectoration (CSE), exacerbations, airflow obstruction, and emphysema in patients with alpha(1)-antitrypsin deficiency (alpha(1)-ATD) [PiZ]. Second, to use multivariate analysis to determine how these factors influence health status. DESIGN: Cross-sectional, single-center. SETTING: UK center for alpha(1)-ATD, university teaching hospital. PATIENTS: One hundred seventeen nonsmoking patients underwent lung function testing, high-resolution CT (HRCT) scanning with density mask analysis, and health status assessment using the St. George's Respiratory Questionnaire (SGRQ) and short form 36 (SF-36) health survey questionnaire. RESULTS: Patients with CSE (n = 50) had worse postbronchodilator airflow obstruction than those who did not (p = 0.03), with a median FEV(1) of 1.15 L (interquartile range [IQR], 0.76 to 1.82) vs 1.44 L (IQR, 0.99 to 2.93), respectively, and higher HRCT scan voxel index (VI) values indicating more extensive emphysema (patients with CSE: median lower zone VI, 50; IQR, 28 to 61; patients without CSE: median lower zone VI, 41; IQR, 5 to 53; p = 0.04). Patients with CSE also had worse health status, as assessed by the SGRQ (p < 0.01 for all domains) and SF-36 questionnaire (p < 0.05 for seven of nine domains). Exacerbation frequency was greater in those patients with CSE (p < 0.001), with a median of two episodes per year (IQR, 1 to 3) vs 0.66 episodes per year (IQR, 0 to 2) for those without CSE. Stepwise linear regression analysis revealed FEV(1), exacerbation frequency, and lower zone VI to be the most important predictors of health status. CONCLUSIONS: Among patients with alpha(1)-ATD, those with CSE expectoration exhibit greater physiologic impairment and more extensive emphysema than those without. This is reflected in an inferior health status, which is also influenced independently by an increased exacerbation frequency in those with CSE.

Adult↗

Predictors of perceived health status of tuberculosis-infected homeless.

This study examines the predictors of perceived health status among homeless adults with latent tuberculosis (TB) in Los Angeles, especially in relation to gender differences. Total, 415 men and women enrolled in a TB-adherence trial completed baseline assessments concerning health status. Results indicated that women were more likely than men to report being in fair or poor health and to have experienced health problems. More women than men self-reported daily drug use and poor mental health. Homeless women were also more likely than their male counterparts to receive support from non-drug-users. Homeless adults who reported fair or poor health were also more likely than those who reported better health to have used injection drugs, to report experiencing depressive symptoms and poor mental health, and to have been homeless more than 3 years. Predictors of fair or poor health included being female and experiencing more depressive symptoms.

Adult↗

Selected measures of health status for Mexican-American, mainland Puerto Rican, and Cuban-American children.

The 1987 National Vital Statistics System and the Hispanic Health and Nutrition Examination Survey (1982 through 1984) were used to assess the health status of Mexican-American, mainland Puerto Rican, and Cuban-American children by examining the prevalences of pregnancy outcomes and chronic medical conditions. The low-birth-weight rate among Hispanics (7.0%) compared favorably with that of non-Hispanic whites (7.1%) despite the greater poverty and lower levels of education among Hispanics. When examined by Hispanic subgroup, however, significant differences were present, with mainland Puerto Ricans having the highest prevalences of low-birth-weight infants. Premature births were more common among all three Hispanic subgroups than among non-Hispanic whites. Mexican-American and Cuban-American children had a similar prevalence of (3.9% and 2.5%, respectively) chronic medical conditions compared with non-Hispanic white children; Puerto Rican children had a higher prevalence of chronic medical conditions (6.2%). When assessed by these health status indicators, Hispanic children seem to have a health status similar to non-Hispanic white children. However, mainland Puerto Rican children seem at greater risk for poor health, reflecting the US Hispanic population's heterogeneity. Health programs targeted at US Hispanics should appropriately consider these group differences.

Adolescent↗

The influence of general health status and social support on symptomatic outcome following coronary artery bypass grafting.

OBJECTIVES: To assess health status, level of social support, and presence of coronary artery disease risk factors before and after coronary artery bypass grafting (CABG); to assess symptomatic relief approximately 12 months postoperatively; and to examine the association between preoperative health status and recurrence of symptoms. DESIGN: Observational study. SETTING: Preoperatively, in hospital outpatient department (1995-1996); postoperatively, at home (1996-97). SUBJECTS AND METHODS: Patients awaiting elective CABG were recruited one month before the expected date of operation. Preoperative assessment included severity of symptoms, coronary artery disease risk factors, short form 36 (SF-36) questionnaire, and social activities questionnaire. The presence and severity of angina and breathlessness were reported postoperatively (mean 16.4 months). Multiple regression analysis was used to identify factors associated with improved outcome following CABG. MAIN OUTCOME MEASURE: Patient reported presence and severity of angina and breathlessness. RESULTS: 183 patients were followed for a mean of 16. 4 months after CABG. Angina and breathlessness were completely relieved in 55% and 36% of patients, respectively. In patients with residual symptoms, the severity was significantly reduced (angina p < 0.001; breathlessness, p = 0.02). Patients with low SF-36 scores and low social network scores preoperatively were less likely to be relieved of symptoms (p < 0.001). Health status and social support levels preoperatively were lower than in other reported coronary artery disease patients groups. Preoperatively, coronary artery disease risk factors were higher than recommended in current guidelines: 67.4% had raised plasma cholesterol, 39.0% were hypertensive, 80% were moderately obese, and 22.9% were smokers. CONCLUSIONS: Recurrence of symptoms exceeded other published studies. Patients' perception of general health, symptoms, and social support influences outcome.

Adult↗

The relationship of cardiovascular and psychological impairments to the health status of patients enrolled in cardiac rehabilitation programs.

BACKGROUND AND PURPOSE: Understanding the causes of differences in disability among individuals is an important research focus for rehabilitation professionals. The purpose of this study was to examine the relationship between health status and the impairments commonly associated with cardiovascular pathophysiology. SUBJECTS: The subjects were patients (N=789) enrolled in 13 cardiac rehabilitation programs in Massachusetts. METHODS: Data were collected on psychological and physiological impairments, demographic characteristics, and health status. Multivariate analyses were used to determine which measures of impairment and patient characteristics were related to health status. RESULTS: Psychological impairment was related to all scales of the MOS 36-item Short-Form Health Survey (SF-36). Very few measures of physiological impairment and individual characteristics were related to SF-36 scores. The models accounted for 16% to 57% of the variability of the instrument's scales. CONCLUSION AND DISCUSSION: In patients entering cardiac rehabilitation, psychological distress is related to poor health in both the physical and psychological dimensions. Variability in health status is not well explained by traditional measures of impairment or demographic characteristics. Physical therapists working to address their patients' health needs must consider collecting data, setting goals, and devising interventions that address psychological impairment.

Adult↗

Mental health status and visit rates of active duty members and their families: findings from the 1994-1995 Department of Defense Health Beneficiary Survey.

Determining whether there is evidence of underutilization of outpatient mental health care by Department of Defense (DoD) beneficiaries relative to the general population is the purpose of this study. It analyzes data from the 1994-1995 DoD Health Beneficiary Survey and compares the mental health status and usage rates of active duty members and their families with benchmark levels found in the general population. Although the mental health status for the DoD beneficiary population was found to be generally the same as that of the general U.S. population within gender categories, gender-specific usage rates of mental health services of DoD beneficiaries in the groups examined were well below rates recorded for the general population. The concept of psychological readiness is also introduced. Several recommendations for increasing access to mental health care are presented.

Female↗

[Problems in maintaining and improving health status in small ethnic groups of the North].

The paper provides the materials of studies of the health status, living conditions, and environment of small peoples of the North. The conditions of the North are shown to have a negative impact on the health status of the population. There is a high incidence of tuberculosis among the peoples. The health care system in the North should be organized in terms of a comprehensive assessment of the health status of various populations of small peoples, the prevalence and clinical features of pathological processes and ecological and economical factors.

Arctic Regions↗

Health status of hostel dwellers. Part I. Introduction, methodology and response rates.

A health status survey (October-November 1987) was carried out among the residents of the urban migrant council-built hostels outside Cape Town at Langa, Nyanga and Guguletu, at their request. The project is introduced and the basis for the interpretation of the findings is provided. Migrant labour and the resultant material and physical impoverishment provide the social context for this study. The hostel dwellers as a migrant or mobile population presented certain research challenges. The working concepts, including the notion of the 'bedhold', employed in this study to address the mobility of the population are outlined. the methodology describes how the range of criteria selected to measure health status was investigated in a single survey. The response rates suggest that surveys carried out in the urban location of a migrant labour situation do not access the poor in the broader migrant labour situation. Findings are treated with caution for what they infer for the broader migrant population.

Data Collection↗

Health status of children with moderate to severe cerebral palsy.

The aim of the study was to evaluate the health of children with cerebral palsy (CP) using a global assessment of quality of life, condition-specific measures, and assessments of health care use. A multicenter population-based cross-sectional survey of 235 children, aged 2 to 18 years, with moderate to severe impairment, was carried out using Gross Motor Function Classification System (GMFCS) levels III (n = 56), IV (n = 55), and V (n = 122). This study group scored significantly below the mean on the Child Health Questionnaire (CHQ) for Pain, General Health, Physical Functioning, and Impact on Parents. These children used more medications than children without CP from a national sample. Fifty-nine children used feeding tubes. Children in GMFCS level V who used a feeding tube had the lowest estimate of mental age, required the most health care resources, used the most medications, had the most respiratory problems, and had the lowest Global Health scores. Children with the most severe motor disability who have feeding tubes are an especially frail group who require numerous health-related resources and treatments. Also, there is a relationship among measures of health status such as the CHQ, functional abilities, use of resources, and mental age, but each appears to measure different aspects of health and well-being and should be used in combination to reflect children's overall health status.

Activities of Daily Living↗

A tool to measure the change in health status of selected adult patients before and after intensive care.

If the effect of intensive care on the patient is to be fully assessed then the health status of patients before and after admission to ICU must be measured. The validity of a simplified system which can also use relatives, where necessary, as informants on the patients' pre-morbid health status has been evaluated. In a District General Hospital Intensive Care Unit a questionnaire based survey of 85 patients admitted over a period of eight months used a new specially-designed instrument and compared this with the Functional Limitations Profile (FLP) and the Perceived Quality of Life instrument (PQL). Relatives completed the health status questionnaire as soon as possible after the patient's admission and patients completed a suitably modified version at discharge from ICU. Patients were sent the FLP, PQL and modified health status questionnaire six months and one year after discharge. Questionnaires were completed by 59 paired relatives and patients. Questions were answered in the same way by relatives and patients; 42 of the 59 pairs of results were in agreement within two points of better or worse health. The closest responses were provided by wives in daily contact with their partner. At six months post ICU discharge, 49 patients completed the follow-up questionnaires, 12 patients had died and three were too confused to co-operate. Twenty-one patients (25%) were lost to follow-up. At one year post ICU discharge, 43 patients completed the follow-up questionnaires, one other patient had died and three still remained confused.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Interpretation of change scores in ordinal clinical scales and health status measures: the whole may not equal the sum of the parts.

The objective of this study was to analyze the problem of interpreting change scores of ordinal health status measures for clinical research or practice. Methods used included exploration of the generation of change scores in the physical ability scale of the SF-36, one of the most widely used generic health status instruments. Resulting data are presented as the ranking of items according to baseline score; a percentage of patients with severe difficulty and Rasch analysis provided the same rank order of item difficulty. On the interval scale provided by the Rasch model a concentration of items reflecting moderate difficulty occurred. This "inflates" numerical gains for patients with moderate disability compared to patients with very severe or minor physical disability. Calibration of change scores using patient perception of the level of change in function showed important variation of numerical gains with baseline. We conclude that numerically equal gains may differ in their meaning depending on baseline health status. It is recommended that distribution of baseline health status measures and distribution of responders by baseline status be reported in evaluative studies.

Data Collection↗

[An approach to "quality-adjusted life years" quality of life weights from self-assessed health status].

OBJECTIVES: To estimate quality of life weights in Spain for 1987, 1993 and 2001, based on self-assessed health status reported in the National Health Survey. MATERIAL AND METHODS: Quality of life weights were estimated using an ordered probit model. In this model, self-assessed health status was related to the presence of chronic diseases, demographic characteristics, and a random error. Quality of life weights were derived by normalizing the regressors obtained. RESULTS: Quality of life values related to chronic diseases varied depending on the diseases. Pain, limitations, and diseases in the previous 12 months had a greater negative impact on quality of life than did chronic diseases. Quality of life decreased as age increased, and increased as educational level increased. For the same disease and adjusted for age, sex, and educational level, quality of life weights were greater for 1993 and 2001 than for 1987. CONCLUSIONS: The proposed methodology allows quality of life weights to be calculated from health survey data, which has direct application in economic assessment, analysis of socioeconomic health inequalities, and health capital estimation.

Adult↗

Caregiver burden, time spent caring and health status in the first 12 months following stroke.

OBJECTIVE: To quantify time caring, burden and health status in carers of stroke patients after discharge from rehabilitation; to identify the potentially modifiable sociodemographic and clinical characteristics associated with these outcomes. METHODS: Patients and carers prospectively interviewed 6 (n=71) and 12 (n=57) months after discharge. Relationships of carer and patient variables with burden, health status and time analysed by Gaussian and Poisson regression. RESULTS: Carers showed considerable burden at 6 and 12 months. Carers spent 4.6 and 3.6 hours per day assisting patients with daily activities at 6 and 12 months, respectively. Improved patient motor and cognitive function were associated with reductions of up to 20 minutes per day in time spent in daily activities. Better patient mental health and cognitive function were associated with better carer mental health. CONCLUSIONS: Potentially modifiable factors such as these may be able to be targeted by caregiver training, support and education programmes and outpatient therapy for patients.

Activities of Daily Living↗

[Problems of the health status of the youth from a student town].

Studies are carried out on the health status and morbidity of students from the territory of the student town and health-hygienic undertakings are recommended for improving the health of the students and formation of health habits. For 8000 students were traced the following data: prophylactic examinations, acute morbidity, morbidity according to medical registrations studied from the statistical cards, the follow-up care of patients with chronic diseases. A scientific statistical method for studying the medical documentation is used for examining the acute and chronic morbidity. The basic moments in the structure of the students pathology are described, stimulated by the new moments of life in the conditions of the students town and the peculiarities in the health status of the students as special age group of the population. Conclusions are made concerning the carrying out of directed hygiene-preventive undertakings.

Bulgaria↗

Effects of chromium on health status, blood neutrophil phagocytosis and in vitro lymphocyte blastogenesis of dairy cows.

The objective of this study was to determine the effects of supplemental dietary chromium (Cr) on health status and mastitis-related parameters, as well as neutrophil phagocytic activity of dairy cows during late pregnancy and early lactation. In addition, possible interactions and involvements of Cr with insulin, cortisol, somatotropin (rBST) and insulin-like growth factor-1 (IGF-1) were directly investigated in vitro based on blastogenic responses using peripheral blood lymphocytes (PBL) of eight cows fed the control diet. Forty pregnant Holsteins, 18 primiparous and 22 multiparous, at week (wk) 6 before the expected calving dates were randomly assigned to treatments: control and supplemental chelated Cr (0.5 ppm) in the diet. All cows were managed in a normal production operation and health status was assessed by recording the incidence of health problems during the experimental period of wks 6 before and 16 after calving (-6 to 16 wks). Mastitis-related parameters included somatic cell counts (SCC), bacterial colony counts of milk samples from each mammary gland quarter of all cows during wk 1 to wk 8 postpartum. Peripheral blood neutrophil phagocytic function of eight cows fed either control or supplemental Cr diet was determined by the ability to take up uniform fluorescent beads measured by flow cytometry. Supplemental Cr had no effect (P > 0.10) on health status of cows during late pregnancy and early lactation, or on SCC and bacterial colonies of quarter milk samples from early lactation (wks 1 to 8). Supplemental Cr also did not affect neutrophil phagocytic function of cows from 6 wks prepartum to 6 wks postpartum. However, in the in vitro study of PBL (from control animals, not fed Cr diet) blastogenesis with addition of insulin or cortisol at two levels (0.05 and 0.5 ng ml-1), insulin and cortisol enhanced or had no effect on PBL proliferations with or without concanavalin A (con A) simulation. However, further Cr addition in the culture medium containing supplemental insulin or cortisol, particularly CrCl3, additively increased (P < 0.05) BPL blastogenic activities with or without con a stimulation. Conversely, addition of rBST or IFG-1 (0.5 and 5.0 ng ml-1) in the culture medium enhanced PBL proliferation, but addition of Cr gave no additional effect. These results indicated that supplemental Cr had no beneficial effect on health status, mastitis-related parameters or neutrophil phagocytic activity of dairy cows. However, in vitro study confirmed and extended our previous observations that Cr has an effect on lymphocyte proliferation and this may associate with insulin or cortisol actions.

Animal Feed↗