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PubMed1987

A psychophysical technique for measuring cone photopigment bleaching.

A new, clinically applicable test has been developed to measure the bleaching of the foveal cone photopigments. This noninvasive test is called steady-state color matching. Steady-state color matching is based on the dependence of a color match on the optical density of the cone photopigments. By measuring the color match as a function of retinal illuminance, it is possible to compute the optical density of the cone photopigments at each illuminance. Thus, abnormalities of photopigment bleaching can be detected. This study demonstrates that the technique is readily performed by a clinical population. Patients with central serous retinopathy and retinitis pigmentosa are shown to have low effective optical densities.

Adolescent↗
PubMed1987

Cone photopigment bleaching abnormalities in diabetes.

We have used a color-matching technique to obtain estimates of the optical density of cone photopigments as a function of retinal illuminance in patients with insulin-dependent diabetes mellitus (IDDM). We found that the half-bleach illuminance of some patients is abnormally high. That is, it takes more light to bleach an equivalent amount of photopigment in these patients. Since low illuminance color matches for these patients are normal, this implies that these patients have normal amounts of photopigment, but the photopigment is not bleaching normally. This result clearly points to abnormalities in the outer retina of these diabetic patients. The most likely causes of this abnormality are either decreases in the ability of the cones to absorb light, or an increased rate of regeneration of the cone photopigments.

Adolescent↗
PubMed1986

Visual acuity.

Explore the source record for details and available documents.

Color Perception↗
PubMed1985

[Effect of hormonal contraceptives and caffeine on the Farnsworth-Munsell 100-hue Test].

The Farnsworth-Munsell-100 Hue-Test (FMT) shows an increasing importance for judgement of colour vision disturbances and drug side effects on the ocular system, respectively. Because of the widening of caffeine use, the high incidence of intake of oral contraceptives and the absence of prospective studies, it is necessary to do it to investigate the possibility of influences on colour vision. 206 test persons of both sexes took part in our investigation with the FMT to clear influences of caffeine, oral contraceptives and the combination of both of them. A remarkable result is that caffeine with intake of oral contraceptives diminished the ability of colour discrimination in a wide range of visible coloured light. These investigations are in addition to views known from relevant literature.

Adolescent↗