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Normal reference-intervals for 20 biochemical variables in healthy infants, children, and adolescents.

We determined normal reference values from data on sera of 2099 outpatient children (ages one week to 14 years) at our institution. Using a continuous-flow instrument (SMAC, Technicon), we determined the following analytes in each serum sample: glucose, creatinine, uric acid, inorganic phosphorus, sodium, potassium, chloride, total CO2, iron, cholesterol, triglycerides, total protein, albumin, total bilirubin, creatine kinase, lactate dehydrogenase, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, and calcium. The resulting data were coded and subsequently processed in an IBM 370 computer, and the reference values (3rd and 97th percentiles) were defined for each analyte. A two-way analysis of variance was also done to determine the influence of age and sex on results of these 20 biochemical tests.

Adolescent↗

Ethnographic and secrecy patterns among drug abusers.

The underground nature of drug abuse is a major cross-national barrier to the collection of sound epidemiological data. The authors examine some common patterns of secrecy developed by drug abusers to avoid social disapproval or punishment in different socio-cultural settings. Assurances of anonymity and confidentiality may not be sufficient to make the majority of heavy drug abusers "visible" to the researcher. One way to overcome this barrier is to train field staff to recognize certain ethnographic signs i.e. the specific appearance and behaviour of drug abusers that can facilitate identification of target populations.

Amphetamines↗

Pulmonary alveolar microlithiasis with an unusual radiological pattern.

We present a case of pulmonary alveolar microlithiasis with an unusual radiological pattern in an an otherwise asymptomatic young woman. It was characterized by a reticulonodular pattern predominantly in the lower lung fields with Kerley B lines. The diagnosis was made by transbronchial lung biopsy. We found an otherwise asymptomatic brother with the same radiological pattern.

Adult↗