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[Cardiovascular changes based on ECG data in workers involved in the elimination of the sequelae of the accident at the Chernobyl Atomic Electric Power Station].

122 persons who had participated in the Chernobyl nuclear power station disaster control were passed through ECG examinations, as a result of which susceptibility to bradycardia was revealed. To exclude a marked vagal influence on the myocardium, orthostatic, atropine and ephedrine tests were performed. Weakened reactions to atropine and ephedrine indicated a secondary vagotomy caused by the lowered sensitivity of beta-adrenoreceptors.

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[Genetic effects in mice exposed to the 10-km area around the Chernobyl Atomic Energy Station].

Mice (CBAxC57BL) F of both sexes were exposed within the 10 km zone of Chernobyl nuclear power station. Genetic damage of phone chronic effect of increased radiation in exposed adult mice and in the course of embryogenesis was studied. The total absorbed radiation doses in testes varied from 1.85 to 0.42 Gy in embryos and from 3.4 to 2.7 Gy in adult males. Increase of dominant lethal mutations (DLM) and abnormal sperm heads (ASH) was only observed right after the end of exposure of adult males. The yield of reciprocal translocations (RT) in these males was relatively low. Among the males exposed at the stage of early embryogenesis, 4 heterozygotes for RT were revealed. In other males of this group the RT yield was low.

Animals↗

[Pregnancy outcome in some Norwegian counties before and after the Chernobyl accident].

The outcome of pregnancies in six countries in Norway has been studied during 12 months prior and subsequent to the Chernobyl accident. The accident took place in a period with an annual increase of births of approximately 3%. However, the year after the accident a decrease of 0.7% was observed with particularly low numbers during February--April 1987. Concomitantly, the miscarriage fraction of all pregnancies increased by 16.3% and particularly during November 1986--January 1987. The same pattern was found when observations from Haukeland Hospital were analyzed separately. When the time of conception was taken into consideration we found that conceptions during the period May--July 1986 ended more often as miscarriages. We have no explanation of the observations. The external radiation exposure seems too small to have produced these effects. The internal radiation from food may have played a role. People may also have changed their food intake, using less vegetables, due to fear of these being polluted by radioactive fallout.

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[Health protection after the Chernobyl accident. The relation of costs and reduction of radioactive dosage level].

This article describes the nutritional measures introduced to protect health after the Chernobyl accident, and the associated costs. The total value of the reindeer meat, mutton, lamb and goat meat saved as a result of such measures in 1987 amounted to approx. NOK 250 million. The measures cost approx. NOK 60 million. The resulting reduction in the radiation dose level to which the population was exposed was 450 manSv. In 1988, mutton/lamb and goat meat valued at approx. NOK 310 million was saved from condemnation by similar measures, which cost approx. NOK 50 million. The resulting dose level reduction was approx. 200 manSv. The relationship (cost/benefit ratio) between the overall cost of the measures taken to reduce radioactivity levels in food and the dose level reduction achieved was acceptable.

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[The direct use of cytogenetic data for plotting prognostic curves of the dynamics of neutrophil count after acute relatively uniform gamma irradiation (based on data from the victims of the accident at the Chernobyl Atomic Electric Power Station].

A considerable number of irradiated persons appeared as a result of the accident at the Chernobyl Atomic Power Station. Analysis of chromosome aberrations and detailed hematological investigations were performed in them. Relatively uniform affection of the hemopoietic tissue could be anticipated on the basis of the results of the cytogenetic analysis in most of these persons who had been exposed to radiation at doses that were critical for the development of the bone marrow syndrome. It made it possible to establish direct quantitative relationship between the indices of a postradiation curve of the time course of the neutrophil count in peripheral blood and the mean rate of dicentrics in lymphocytes for cases of relatively uniform irradiation and to plot prognostic curves of neutrophils for different frequencies of dicentrics.

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[The contamination of food trout and carp from Bavarian fish farms with radiocesium (Cs-137 + 134) 1986 to 1989 as the result of the nuclear power plant accident at Chernobyl].

After the nuclear power station accident of Chernobyl at 26. 4. 86 Southern Bavaria was contaminated with radionuclides as J-131, Cs-137 and Cs-134. After three months only the Cesium nuclides had bearing on food, accordingly for fish. The accumulation of total Cesium (137 + 134) in the muscle of trout and carp had reached levels of 30 and 80 Bq/kg on an average and levels for 300 and about 800 Bq/kg were determined as maximum. The more naturally fed carps had have in the first two years a higher accumulation than the trout. Then the accumulation was equally on a low level near zero.

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[A pharmacokinetic approach to studying the uptake of 137Cs by children following the reactor accident at Chernobyl].

The course of 137Cs content of children after the reactor accident of Chernobyl measured by means of a whole-body counter could be reconstructed theoretically by a pharmacokinetic model. The children of the kindergarten of the hospital of the University of Cologne accumulated during the vegetation periods 1986/87 (I) 86.9, 1987/88 (II) 114.4 and 1988/89 (III) 24.4 Bq 137Cs per kg body weight.

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Effects of the Chernobyl accident on animal husbandry and production, from a Swedish perspective.

About 20% of the Swedish land area was considerably contaminated by radionuclides released by the nuclear accident at Chernobyl, Ukraine, in April 1986. However, less than 10% of the arable land was contaminated. The heavy contamination was closely correlated with the amount of rain received during the first days of May 1986. Immediate restrictions on grazing limited the early uptake of contaminants in animal products. Changes in management of animals, especially sheep, goats, and reindeer in the contaminated areas have effectively reduced the transfer of radionuclides to human beings. One important factor was the possibility of obtaining uncontaminated feeds from unaffected parts of the country. The direct costs during the first 2 years after the accident were approximately +10 million for analyses and +90 million for compensation to farmers for condemned products (milk, mutton, and reindeer meat) and reimbursement for purchase of uncontaminated feeds from other parts of the country.

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[Estimation of absorbed dose based on the results of cytogenetic studies of lymphocyte cultures from subjects exposed in the accident at the Chernobyl Atomic Power Station].

Cytogenetic analysis of peripheral blood and bone marrow lymphocyte cultures was performed in 158 persons who had suffered in the accident at the Chernobyl Atomic Power Station. According to these data, in spite of severe local injuries in some cases, hemopoietic tissue of a majority of the patients was exposed to relatively homogeneous irradiation. Doses, estimated by the frequency of dicentrics (per 100 cells), in 7 patients varied within the ranges 10.1-13.7 Gy, in 12--6.1-9.5 Gy, in 16--4-5.8 Gy, in 33--2-3.9 Gy, in 19--1-1.9 Gy, in 42--0.1-0.9 Gy. Dicentrics in 29 patients were undetectable.

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[Mental disadaptation in emergency situations (accident at the Chernobyl nuclear power station)].

Phenomenology and time course of psychic disorders in persons exposed to life-threatening emergency situations provoked by the Chernobyl accident have been analyzed. Three states could be identified according to differences in their psychogenic impact: acute, delayed and long-term. Psychic dysadaptation and disorders might be presented as results of a single process beginning with acute anxiety responses followed by asthenic disorders which backed the relatively steady neurotic and psychopathic states.

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[Combined antibiotic therapy of acute radiation disease in persons affected during the accident at the Chernobyl nuclear power station].

One hundred and fifteen patients with acute radiation disease of degrees I to IV affected during the accident at the Chernobyl APS were treated in a specialized hospital. The anti-infection regimen included isolation, air sterilization with ultraviolet light, intravenous administration of broad spectrum of antibiotics (gentamicin, cephalosporins and carbenicillin) and nystatin. Some cases were treated with amphotericin. Some cases were treated with amphotericin B. Out of 22 patients who died at the early periods (days 14 to 34) or at the period of agranulocytosis in 7 patients sepsis was stated. In 5 of them it was complicated by pneumonia. In 5 patients who died at the late periods (days 48 to 99) or at the period of hemopoiesis normalization infectious complications by the death moment were stated: sepsis in 3 patients and pneumonia in 2 patients. The aspect of the microbiological diagnosis and therapy efficacy is discussed.

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Radiocesium levels measured in breast milk one year after the reactor accident at Chernobyl.

One hundred-two samples of colostral milk, collected during spring of 1987, approximately one year after the reactor accident at Chernobyl, were measured for radiocesium contamination. The data showed a normal-type distribution with a mean contamination concentration of 16.4 Bq L-1. A weak correlation of the data to the mothers' diet was established by taking into account four of the main staples in the area. The corresponding transfer coefficient was deduced with a value of fm = 0.06 +/- 0.03 d L-1. The resultant effective dose received by breast-feeding infants was estimated, on the average, as 0.012 mrem d-1.

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Chernobyl--the radiological impact on Canada.

On 26 April 1986, an accident at a Ukrainian nuclear reactor at Chernobyl triggered the release of large quantities of fission products into the atmosphere. After 7 May 1986 measurable quantities of ruthenium-103, iodine-131, cesium-134, and cesium-137 were detected in environmental sampling carried out in all regions of Canada. Maximum airborne concentrations for each radionuclide were of the order of a few mBq.m-3 and contaminated milk samples on average contained less than 1Bq.L-1 of iodine-131 and cesium-137. The mean value of the effective dose equivalent for an adult Canadian in the two months following the accident is calculated to be 0.28 microSv. As this total radiation dose is about 10(-33) of the dose from natural background during the same period, the resultant radiological detriment is concluded to be negligible.

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After Chernobyl--how U.S. physicians respond to radioactive fallout.

On April 26, 1986, a reactor unit at the Soviet Union's Chernobyl Power Station exploded, and substantial amounts of radioactive material were released. Fallout from this incident was deposited in the United States and elsewhere. Radioactive fallout is a major concern for obstetricians and pediatricians; their patients are the most vulnerable to the adverse effects of radiation. This study addresses the question: What are these physicians' perceptions and beliefs about fallout and its effects on their patients? A questionnaire was developed to measure these perceptions and beliefs. This instrument was mailed in November 1986 to all obstetricians and pediatricians listed in the telephone directory for western Massachusetts. A factor analysis of the physicians' responses yielded five factors: concern for patients, management of risk, effect of fallout, physicians' role in prevention, and guidance on advising patients. The physicians' responses to patients' inquiries were categorized as giving information, reassurance, and prescription. The authors recommend that the study be replicated with a more representative sample, that professional medical groups provide reliable information to members, and that physicians ask their professional organizations to address the issue of physician participation in the national planning process relevant to their concerns about radioactive fallout.

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Thyroid uptake of iodine-131 and iodine-133 from Chernobyl in the population of southern Sweden.

The accident at the nuclear power plant of Chernobyl on April 26, 1986 led to radioactive contamination of many countries including Sweden. The population was exposed to released radionuclides, both by inhalation and from contaminated food. We have studied the content of gamma-emitting radioisotopes in the thyroid glands of a normal population from southern Sweden using measurements of samples taken at autopsy. The first samples are from a person who died on April 27, 1986. This report contains results for 131I and 133I. The time-activity curve for 131I shows an immediate uptake with a maximum 18-26 days after the accident. No measurable levels were observed after 93 days. We have found that the increase in dose equivalent to the thyroid for the population of southern Sweden due to the released 131I and 133I will be less than 0.1 mSv. This may lead to an increase in the incidence of thyroid cancer of 0.1% during a period of 25 yr.

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Soviet medical response to the Chernobyl nuclear accident.

The nuclear accident at Chernobyl was the worst in the history of nuclear power. It tested the organized medical response to mass radiation casualties. This article reviews the Soviet response as reported at the 1986 postaccident review meeting in Vienna and as determined from interviews. The Soviets used three levels of care: rescue and first aid at the plant site; emergency treatment at regional hospitals; and definitive evaluation and treatment in Moscow. Diagnosis, triage, patient disposition, attendant exposure, and preventive actions are detailed. The United States would be well advised to organize its resources definitively to cope with future nonmilitary nuclear accidents.

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[Measurements of radiocesium incorporation in 250 deceased patients who died within a year following Chernobyl].

Two months after the nuclear accident of Chernobyl, postmortem measurement of radiocaesium (137 Cs and 134 Cs) were started in different organs to study incorporation, organ distribution, and kinetics. 250 corpses were examined between July 1986 to August 1987 in the Department of pathology, St. Pölten. Highest concentrations were found in skeletal muscles, with a median value of 2.3 pCi/g wet weight (80-90% of the total incorporated dose), followed by liver, lung, spleen, kidneys, thyroid gland, heart, blood and brain, with values between 0.8 and 1.3 pCi/g. No caesium was detectable in fatty tissue. During the observation period an increase in caesium concentration was observed in almost all organs. The concentration almost doubled within 10 months in skeletal muscles. Only the lung demonstrated a decrease in the radiocaesium concentration within the first months, which can be explained only by inhalation of radiocaesium. A statistically significantly higher caesium concentration in most organs was found in females as compared with males. A possible explanation is the known lower urinary caesium concentration in women. Statistically significant correlations were found between caesium concentration and nutritional status, presence of malignancy, and the most recent intravital serum creatinine value.

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[One year after Chernobyl--radioactive cesium in breast milk].

Radioactivity in human breast milk was determined in 32 women in February and March 1987 by means of a Germanium detector. At this time radioactivity increased again by feeding the hay to the cattle harvested in the weeks following the disaster of Chernobyl. 8 (25%) of the values were above 0.3 nCi/l for babies milk recommended by the local authorities.

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