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PubMed1998

[Bandages with proteolytic enzymes in the treatment of purulent wounds].

Clinical trial of well-known and available in Russia enzyme-containing dressings (ECD): dalcex-tripsin and its modification--tripsin-chlorhexidin and tripsin urea containing, profezim, sipralin, lysosorb, collavin and teralgim. The most effective ECD for cleansing of festered wounds, burns and trophyc ulcers are collavin and lysosorb (application wound draining sorbents from helevin and proteolytic enzymes--collagenase of crab and terrylytin, respectively). Combined usage of sorbents and antiseptics substantially increases their curative properties. The other ECD have some shortcomings (low sorption and draining) which makes it possible to recommend them at present time only for limited usage. Draining sorbents and their combinations hold promise for field surgery, pyogenic traumatology, combustiology, cryopathology, gynecology, otolaryngology, neurosurgery, dermatology.

Administration, Topical↗