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PubMed1997

[Geographical informational technology as the basis for the informational integration for the large-scale evaluation of the environment].

Complex evaluation of environmental state requires processing of extensive information describing various components and objects of environment. Characteristic of this information is territory fix--each environmental object has definite geographic position and border. The authors discuss effects of up-to-date geographic information technologies on evaluation of environmental state in Bashkortostan Republic. Examples of analysis and simulation of possible changes in environmental state are given.

Bashkiria↗
PubMed1976

Research data integrity: a result of an integrated information system.

The toxicologic problems of today frequently require long-term, multidisciplinary experimentation involving large numbers of animals. In order to provide the extensive safety evaluation necessary to produce data that can be reasonably extrapolated to humans, automated research support systems have transcended the position of useful tools and have become an integral part of the total design of experimental protocols. For an automated information system to fully represent the reality of the experiment, it must be able to assure integrity, as well as provide for the storage, calculation, and retrieval of data values of the quality and quantity necessary for fulfilling protocol requirements. Guarantees against error and loss of data, in addition to flexibility and easy access, must be an inherent part of the system if the acceptance and condifence of the investigator are to be obtained. This paper discusses the criteria, philosophies, and benefits of integrated data systems that ensure integrity of toxicologic research support.

Computers↗
PubMed2003

Information integration in judgements of time to contact.

Time to contact (TTC) is specified optically by tau, and studies suggest that observers are sensitive to this information. However, TTC judgements also are influenced by other sources of information, including pictorial depth cues. Therefore, it is useful to identify these sources of information and to determine whether and how their effects combine when multiple sources are available. We evaluated the effect of five depth cues on TTC judgements. Results indicate that relative size, height in field, occlusion, and motion parallax influence TTC judgements. When multiple cues are available, an integration (rather than selection) strategy is used. Finally, the combined effects of multiple cues are not always consistent with a strict additive model and may be task dependent.

Cues↗
PubMed1988

Integrated Academic Information Management Systems (IAIMS). Part III. Implementation of Integrated Information Services. Integration across institutions: IAIMS extended.

The technologies contributing to today's information world are profound. Electronic technologies are transforming the way we handle information and the medium used to pursue knowledge. What once seemed beyond reach--that computers, communications, information, and knowledge systems could be merged harmoniously to transmit information via networks--is reality today. The Integrated Academic Information Management System (IAIMS) approach for transfer of biomedical information within a medical center also offers opportunities for networks across institutional lines. The tradition of cooperation and resource sharing among libraries makes them logical facilitators of the emerging, universal information environment. The authors present a course of action based on visions of a new era, realities of the present, and strategies for the future.

Academic Medical Centers↗
PubMed1991

INFORM: integrated support for decisions and activities in intensive care.

Many medical decision support systems that have been developed in the past have failed to enter routine clinical practice. Often this is because the developers have failed to analyse in sufficient detail the precise user requirements, because they have produced a system which takes too narrow a view of the patient, or because the decision support facilities have not been sufficiently well integrated into the routine clinical data handling activities. In this paper we discuss how the AIM-INFORM project is setting out to deal with these issues, in the context of the provision of decision support in the intensive care unit.

Artificial Intelligence↗
PubMed1999

Temporal constraints of perceiving, generating, and integrating information: Clinical indications.

Neuropsychological research on temporal constraints of perception and motor performance can add important information to research on human behavior. Without considering temporal mechanisms of perceiving, generating, and updating information, brain mechanisms can never be fully understood. In this study temporal aspects of performance in psychophysical experiments on three different temporal levels (around 30 ms, 300 ms, and 3000 ms) were investigated in patients with acquired brain lesions and a control group without neurological deficits. The patients had acquired focal brain lesions in: anterior (pre-central) regions of the left hemisphere (with non-fluent aphasia), posterior (post-central) regions of the left hemisphere (with fluent aphasia), the left hemipshere in predominantly subcortical regions (without aphasia), or anterior (pre-central) or posterior (post-central) regions of the right hemipshere. Perception of temporal order (20 to 60 ms) was impaired in patients with left-hemispheric post-central lesions; repetitive voluntary action (300 to 500 ms) was affected mostly in patients with left hemi-spheric lesions, both pre-central and post-central; and a deficit in integrating (2000 ms to 3000 ms) information was most pronounced in patients with left and right pre-central lesions. These findings provide insight into the associations between different levels of temporal organisation and circumscribed regions of the neocortex.

Journal Article↗
PubMed2005

Neurons in the rat lateral hypothalamic area integrate information from the gastric vagal nerves and the cerebellar interpositus nucleus.

Previous investigations have demonstrated that the neuronal activity in the lateral hypothalamic area (LHA) is respectively modulated by afferent inputs from the gastric vagal nerves innervating the upper gastrointestinal tract, as well as the cerebellar interpositus nucleus (IN). The aim of this study was to examine whether the gastric vagal and cerebellar IN inputs converge onto single LHA neurons in rats, especially those sensitive to glycemia. Of the 114 LHA neurons recorded, 60 (52.6%) and 51 (44.7%) responded to gastric vagal and cerebellar IN stimulation, respectively. Of the 60 LHA neurons responsive to gastric vagal stimulation, 30 also responded to the cerebellar IN stimulus, indicating a convergence of gastric vagal and cerebellar inputs onto single hypothalamic cells. When the gastric vagal nerves and cerebellar IN were stimulated simultaneously, a summation of the responses was observed in all 6 neurons tested. Moreover, of 24 neurons that responded to both the gastric vagal and cerebellar IN stimuli, 15 (62.5%) were identified as glycemia-sensitive. These results demonstrate that the visceral information transmitted by the gastric vagal nerves and the somatic information forwarded by the cerebellar IN converge onto single LHA neurons, especially those sensitive to glycemia. The findings also suggest that integration of somatic-visceral responses related to short-term feeding regulation may take place in the LHA.

Animals↗
PubMed2005

Current status of integrating information technologies into the clinical research enterprise within US academic health centers: strategic value and opportunities for investment.

Little information exists about the incorporation of information technologies (ITs) into clinical research processes within US academic health centers (AHCs). Therefore, we queried a group of 37 leading AHCs regarding their current status and future plans in clinical research IT. The survey specifically inquired about the presence or absence of basic infrastructure and IT support requirements; individual applications needed to support study preparation, study conduct, and its administrative support; and integration of data from basic research, clinical trials, and the clinical information systems increasingly used in health care delivery. Of the 37 AHCs, 78% responded. All strongly agreed that a "state-of-the-art" clinical research IT program would be ideal today and will be essential tomorrow. Nonetheless, no AHC currently has an IT solution that even approached this ideal. No AHC reported having all of the essential management foundations (ie, a coherent vision, an overall strategy, a governance structure, and a dedicated budget) necessary to launch and sustain a truly successful implementation of a cohesive clinical research IT platform. Many had achieved breakthroughs in individual aspects of clinical research IT, for example, adverse event reporting systems or consent form templates. However, overall implementation of IT to support clinical research is uneven and insufficient. These data document a substantial gap in clinical research IT investments in leading US AHCs. Linking the clinical research IT enterprise with its clinical operations in a meaningful fashion remains a crucial strategic goal of AHCs. If they are to continue to serve as the "translational research engines" that our society expects, AHCs must recognize this gap and allocate substantial resource deployment to remedying this situation.

Academic Medical Centers↗
PubMed1970

Integrating information services for dental schools into a health sciences library.

Standards for dental school libraries are first discussed, and the actual state of such libraries described. Advantages and disadvantages of combining the dental library with the health sciences library are weighed. A description is given of the experience at UCLA of integrating dentistry into the total Biomedical Library, with details on serial and monograph selection, together with figures on the size of the collection. Services required of a dental library are detailed, and particular services offered by UCLA described.

California↗