[Current therapy of vascular diseases with carbohydrates, insulin and Filatov's biostimulants].
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INTRODUCTION: Modern concept of acupuncture is based on the fact there are designated locations on the surface of human body, which are related to integrative systems of an organism by means of sensory nerves, correlating and synchronizing organ functioning, depending on external and internal conditions, by means of nervous and neurohumoral regulation of metabolic and regenerative processes, including also mobilisation of immunological, protective and antistress reactions. Apart from standard needle acupuncture, other methods of stimulating acupuncture points are also applied. Due to invention of low power lasers, irradiation laser acupuncture has been introduced into routine medical practice, characterised by painless and aseptic technique and outstanding clinical results. MATERIAL AND METHODS: The investigation was aimed at defining therapeutic effects of low power laser irradiation by stimulating acupuncture points or local treatment of asthma. A prospective analysis included 50 patients treated at the Institute of Pulmonary Diseases in Sremska Kamenica during 2000, 2001 and 2002. Together with conservative treatment of present disease, these patients were treated with laser stimulation of acupuncture points in duration of ten days. During treatment changes of functional respiratory parameters were recorded. Results were compared with those in the control group. The control group consisted of the same number of patients and differed from the examination group only by not using laser stimulation. RESULTS: Patients with bronchial asthma presented with significant improvement (p < 0000,5) of all estimated lung function parameters just 30 minutes after laser stimulation. Improvements achieved on the third and the tenth day of treatment were significantly higher (p < 0.001 to p < 0.00005) in the examination group in comparison with the control group. Further investigation confirmed that improvement of measured lung function parameters was significantly higher in younger patients, in patients whose disease lasted shorter, as well as in women. Patients with asthma, who were treated every three months for a one year period, presented with significantly lower frequency and intensity of attacks. DISCUSSION: The mechanism of laser stimulation activity in treatment of bronchial asthma is explained in detail, correlating our results to those obtained by other authors. CONCLUSIONS: A ten-day course of low-power laser stimulation of acupuncture points in patients with bronchial asthma improves both the lung function and gas exchange parameters. Positive effects of laser treatment in patients with bronchial asthma are achieved in a short time and they last long, for several weeks, even months. Successive laser stimulation in asthmatics prolongs periods of remission and decreases the severity of asthmatic attacks. Better positive effects of laser stimulation are achieved in younger asthmatics, in those with shorter disease history and in female patients. There is a negative correlation between effects of laser stimulation and patients' age and disease history. However, these characteristics do not affect response rate and speed but positive laser stimulation effects are achieved in a shorter period in female asthmatics.
There is described the method of operative treatment of gonarthrosis, ensuring prolonged trophic influence on the articulation by means of slow distraction of osseous transplants from the periarticular knee fragments with its simultaneous decompression at the Ilizarov's apparatus. Prolonged (3 and more months) process of osseous reparation in the immediate proximity of knee joint with simultaneous unloading of articulation cartilage creates better conditions for involutional development of arthrosis with significant decrease of pain syndrome for 20 months, that has been noted with all patients.
The results of operations, ensuring prolonged trophic influence upon hip joint at coxarthrosis by slow distraction of osseous transplant from periarticular fragment at simultaneous decompression of hip joint by Ilizarov's apparatus, are presented. It ensures sufficiently active near-articular osteogenesis up to 3 and more months as well as creates better conditions for articular cartilage regeneration by means of its decompression. During 1.5 years with 4 operated patients there was noted, concurrent with pain decrease, significant increase of movement extent. Roentgenologic examinations indicated broadening of the articular slit with apparent tendency for osteoporosis of periarticular fragments.
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The Authors describe the physical principles regulating interaction between laser beam and living matter. Then they review the biological assumptions that explain the clinical effects on latest experimental data.
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Laser therapy and laser reflexotherapy are perspective for the treatment of atonic trophic ulcers of the lower extremities in patients with chronic venous insufficiency and late radiation ulcers of the skin.
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Content of hexokinase, pyruvate kinase and lactate dehydrogenase was studied in rat callus, formed in presence of commercially available preparations of placental and normal serum albumin. Total activity of all these enzymes was not similar at different stages of healing; the enzymatic activity was closely related to morpho-functional state of cellular structures in repairing zone and was dependent on their maturation. Especially pronounced changes in glycolytic enzymes activity occurred at the period of maximal proliferative activity of osteogenic cells. Placental albumin was shown to exhibit the greater stimulating effect on reparative osteogenesis as compared with the protein from blood serum.
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