Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Typhlitis”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 109 records · Page 6Linked to original sources
PubMed1994

Immunopathologic characterization of typhlitis and colitis in juvenile HLA-B27 transgenic rats.

Adult HLA-B27 transgenic rats carrying high copy numbers of human HLA-B27 and beta 2-microglobulin genes spontaneously develop spondyloarthropathy and enterocolitis comparable to human HLA-B27-associated disease. In this investigation, juvenile HLA-27 transgenic rats were utilized to study incipient immunopathologic events in HLA-B27-associated gastrointestinal inflammation. Flow cytometric analysis of peripheral lymphocytes demonstrated distinctive differences in HLA-B27 protein expression and prompted the division of these transgenic rodents into 2 groups: HLA-B27hi and HLA-B27lo. The HLA-B27hi group, which represented 60% of the rats (aged 8-12 weeks) had inflammation in the colon, anorectal junction and cecum but spared the small intestine. Inflammation coexisted with high levels of surface HLA-B27 expression by hematopoietically derived cells as determined by immunofluorescence staining and flow cytometric analysis of intestinal lymphocytes. Inflammation, which was most intense in the cecum and anorectal junction, was characterized by mixed cellular infiltrate, crypt hyperplasia, transepithelial migration of neutrophils and a reduction in goblet cells. T lymphocytes, particularly CD4+ T cells, predominated over other lymphocytes in the inflammatory infiltrate of the lamina propria. Conversely, no inflammation was evident at any level of the gastrointestinal tract in the HLA-B27lo group (8 weeks of age) which constituted 40% of the juvenile transgenic rats. These animals all expressed low level of HLA-B27 protein. Collectively, these data indicate that HLA-B27 protein expression increases dramatically from 8 to 12 weeks of age and that the level of protein expression and intestinal inflammation are interrelated. These associated gastrointestinal events occur during puberty and thus we speculate that the high level of protein expression may be hormonally mediated.

Animals↗
PubMed1984

Typhlitis: a cause of gastrointestinal hemorrhage in children.

Three children with typhilitis complicating acute leukemia and presenting with severe intestinal hemorrhage are described. The arteriographic findings were hypervascularity of the cecum with intense mucosal staining, opacification of superficial ulcers, and arteriovenous shunting into dilated mesenteric veins. The three children were managed successfully with medical, surgical, and embolic therapies, respectively.

Cecal Diseases↗
PubMed1992

Typhlitis and HIV.

Explore the source record for details and available documents.

Acquired Immunodeficiency Syndrome↗
PubMed2000

Typhlitis.

Explore the source record for details and available documents.

Adolescent↗
PubMedDate not supplied

Pyogranulomatous typhlitis and hepatitis of market turkeys.

Pyogranulomatous lesions in the liver and cecum were observed in groups of 7-to-8-week-old market turkeys. Necropsy revealed multifocal lesions in the liver and the presence of cecal cores that, in some cases, distended the cecum to the point of rupture. Mortality was associated with the ruptured ceca. Two successive flocks also succumbed to these lesions. An epizootiological study was performed to determine the cause and/or initiation of lesions leading to the formation of cecal cores.

Animals↗
PubMed2004

[Prophylactics of postoperative complications in destructive appendicitis and typhlitis].

The method of extraperitonization of the blind gut cupola based on the removable monofilament sutures and drainage of the area was designed, approved in experiments in dogs (n=18) and corpses (n=14) and successfully applied in the clinic (n=25). Unlike the traditional method, the using of this one results in less impaired trophicity, LPO intensification and phospholipase activity of the tissues of regenerating structures that was the grounds of sufficiently rapid reparation process under conditions of inflammation. The proposed complex of surgical measures in patients with destructive forms of acute appendicitis complicated by the inflammatory-necrotic phenomena in the blind gut wall was shown to prevent the development of dangerous postoperative complications, incompetence of the sutures included.

Adolescent↗
PubMed1989

Typhlitis.

Explore the source record for details and available documents.

Agranulocytosis↗