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Time limit and time at VO2max' during a continuous and an intermittent run.

BACKGROUND: The purpose of this study was to verify, by track field tests, whether sub-elite runners (n=15) could (i) reach their VO2max while running at v50%delta, i.e. midway between the speed associated with lactate threshold (vLAT) and that associated with maximal aerobic power (vVO2max), and (ii) if an intermittent exercise provokes a maximal and/or supra maximal oxygen consumption longer than a continuous one. METHODS: Within three days, subjects underwent a multistage incremental test during which their vVO2max and vLAT were determined; they then performed two additional testing sessions, where continuous and intermittent running exercises at v50%delta were performed up to exhaustion. Subject's gas exchange and heart rate were continuously recorded by means of a telemetric apparatus. Blood samples were taken from fingertip and analysed for blood lactate concentration. RESULTS: In the continuous and the intermittent tests peak VO2 exceeded VO2max values, as determined during the incremental test. However in the intermittent exercise, peak VO2, time to exhaustion and time at VO2max reached significantly higher values, while blood lactate accumulation showed significantly lower values than in the continuous one. CONCLUSIONS: The v50%delta is sufficient to stimulate VO2max in both intermittent and continuous running. The intermittent exercise results better than the continuous one in increasing maximal aerobic power, allowing longer time at VO2max and obtaining higher peak VO2 with lower lactate accumulation.

Adult↗

Effect of denture adhesive on retention of the mandibular and maxillary dentures during function.

The purpose of this study was to determine the effect of denture adhesive on retention of mandibular and maxillary dentures over a four-hour period. Denture movements were measured using an alternating magnetic field tracking device that determines the position of magnetic receiver coils relative to a transmitter coil positioned over the head. Ten adults with complete maxillary dentures and complete mandibular implant overdentures were enrolled in the study. Specially fabricated mandibular dentures contained a relief area that exposed the implant post which no longer anchored the denture, but now served as an attachment point for a receiver coil that measured mandibular movement. The denture coil was attached lateral to the post coil on a shelf cut into the denture. Mandibular denture movements were recorded as the difference between the mandible movement signal and the mandible + mandibular denture signals. Measurements of denture movements were made at baseline (no adhesive) and at 0, 2, 4 hours post-adhesive application with Fixodent cream for standardized chewing and biting. The MoveTrack signals were recorded on a digital data cassette recorder for subsequent computer analysis. The results of the measurements were analyzed using paired sample t-tests. Specifically, the following comparisons of movement means were made: mandibular vs. maxillary, baseline vs. post-baseline and successive changes (e.g., baseline vs. hour 0, hour 0 vs. hour 2, etc.). Results of these analyses showed that: 1) mandibular denture movements under both adhesive and non-adhesive conditions were significantly greater than maxillary denture movements; 2) the adhesive significantly reduced movement of the maxillary and mandibular dentures during both chewing and biting; and 3) the improvement occurred immediately post-application of the adhesive and was maintained for the four hours of follow-up.

Adhesives↗

Implementation of a PDA based program to quantify urology resident in-training experience.

INTRODUCTION: There currently is no simple and reliable mechanism for Residency program directors to assess how well their trainees are being exposed to all spheres of their specialty. We report on the use of hand-held personal digital assistants (PDA's) to document all clinical and academic activities of urology residents at one academic institution. MATERIALS AND METHODS: Software was developed to create customized pick lists allowing residents to record all activities on their individual PDA's. Categories included Adult Ambulatory, Pediatric Ambulatory, Adult operative, Pediatric operative, and Academic. Activities were subcategorized into detailed pick lists and time-tracking fields. Residents synchronized with a central database on a standalone hotsync server. RESULTS: In the first 8 months, 21 178 resident-hours and 5333 activities were recorded. Preliminary observations can be made regarding how residents spend the majority of their time: 28% operative, 20% self-study, 19% ward work, 10% Academics, 6% ER consultations, 5% clinic, and 4% inpatient consultations. The most common adult diagnoses encountered while attending to clinic, ward, or ER consultations were lower urinary tract symptoms, urolithiasis and hematuria. Similarly for Pediatrics: neurogenic bladder, antenatal hydronephrosis, infection, and hypospadias were most often reported. Residents reported 5,333 activities, relating to the following spheres of Urology: academics (23%), endourology (18%), oncology (15%), lower urinary tract symptoms (10%), congenital anomalies (5%), urolithiasis (5%), reconstruction (5%), and infection (3%). CONCLUSIONS: This tool provides an objective assessment of resident experience as it relates to selection of rotations, and for addressing curriculum weaknesses. It is applicable at a national level for the study of regional differences in training experience, and trends in graduate Urological education. With minimal effort it could be modified for application to other specialty training programs.

Adult↗

Applications of three dimensional echocardiography beyond the left ventricle: other chambers and structural detail.

The authors' system for quantitative three-dimensional echocardiography (3D echo) now enables analysis of all four heart chambers, valves and associated structures. After image acquisition using freehand scanning and a magnetic field tracking device, the borders of cardiac structures are manually traced. Chambers are reconstructed with a piecewise smooth subdivision surface. The mitral and tricuspid annuli are fitted using a 4 term Fourier series. Other valves and orifices are reconstructed as ellipses. Anatomic labeling enables identification of the chordae, coronary sinus, intervalvular fibrosa, septum, and right and left ventricular apex. The dimensions, shape, and function of cardiac components and the spatial relationships between them such as distance and angle can be determined. These methods provide capability and flexibility for clinical applications such as modeling heart motion, investigating the mechanism of functional mitral regurgitation, and tracking left ventricular remodeling.

Cardiomyopathies↗

A new tool to monitor training and performance of sport horses using global positioning system (GPS) with integrated GSM capabilities.

Global Positioning Systems (GPS) are considered suitable to monitor the position and velocity of horses during cross-country competition or in training. Furthermore, simultaneous recording of life data such as heart rate could be useful to assess the horse's condition during exercise. To test the suitability and reliability of a commercially available GPS system with integrated heart rate recording system and with built in GSM for data transmission, the Fidelak Equipilot Type EP-2003-15/G-2.11 (EP-15/G) was evaluated first for reliability of pulse recording from a pulse generator within the physiological range of horses; furthermore distance, velocity and heart rate recordings were carried out on a standard 1000 m field track with five repetitions. Agreement (% deviation from actually measured distance and from stopwatch-distance based velocity calculations) and variability (Coefficient of Variation for distance, velocity, heart rate) were calculated. From the results it was safe to assume that the heart rate sensor recorded horse heart rates at a high degree of accuracy. Overall distances and velocities are in high agreement with actually measured values. However, overall variability expressed in terms of relative variability (C.V.) is smaller for distance recording (C.V. 0.68%) when compared to velocity (C.V. 1.01%). The system tested is suitable and reliable for simultaneously recording of distance, velocity and heart rates for horses during cross country exercise. GPS-based monitoring of movement along with simultaneous recording of physiological data and the possibility to call upon data will not only be of benefit for training horses or for surveillance during competition, it may also be suitable for distant patient monitoring and in behavioural studies as well as in veterinary medicine in general.

Animals↗

Technique for backward particle tracking in a flow field.

A numerical method to determine the history of particle paths is presented and its application for mixing quantification is illustrated. When more than one source exists in a flow field, the current technique can reveal the particle's identity found in any time and place in the field, by backward tracking its origin. Since the particle position at a preceding time is not known, the velocity vector is implicit. To resolve this uncertainty, a three-stage iterative procedure is developed and implemented. The current particle velocity is multiplied by the time increment and the product is used to estimate the previous time increment particle position. Two velocity matrices are generated on a mesh around the estimated position. The first matrix is the Eulerian velocity field interpolated on the mesh. The second matrix contains velocity vectors that point to the current particle position. A correlation matrix is calculated from the two velocity matrices in order to resolve the actual particle position in the previous time increment. Determination of the time increments' size is performed by checking the maximum of the correlation matrix. The new algorithm was validated using a numerical solution of the confined twin-jet flow at low Reynolds number. This flow performs a Hopf bifurcation at a Reynolds number of about 30, therefore chaotic trajectories might exist in the flow. First, the convergence of the backward particle path to the streamlines in steady flow was demonstrated. Convergence of the particle paths for various time increments was achieved also at the unsteady two-dimensional confined twin-jet flow. When the flow has more than one source, the proposed tracking method can be applied to generate complete and ordered particle source images in any desired position and time in the flow field. Maps of particle sources are used to visualize the flow patterns and the stretched interface between the two fluid sources. Those maps are demonstrated as a powerful tool for mixing quantification and can be implemented also for pollution source detection and many other fluid dynamics applications.

Journal Article↗

Muscle mass of competitive male athletes.

The recent publication of the first validated equation for the estimation of muscle mass (MM) in men has made possible a comparison of MM in athletes from different sports. Limb girths and skinfold thicknesses were measured in 62 male athletes (aged 17-38 years) and 13 non-athletic males (aged 22-36 years). The MM (g) was calculated from the equation MM = S(0.0553 Gt2 + 0.0987 Gf2 + 0.0331 Gc2)-2445, where S is stature, Gt is the mid-thigh girth corrected for the front thigh skinfold thickness, Gc is the maximum calf girth corrected for the calf skinfold thickness and Gf is the uncorrected maximum forearm girth (all in cm). The athletes were classified as gymnasts (n = 10), basketball players (n = 10), body-builders (n = 10), track and field power athletes (n = 12), track and field long sprinters (n = 10) or distance runners (n = 10). The MM means ranged from 38.4 kg for the distance runners to 58.7 kg for the body-builders. Both body-builders and basketball players had significantly greater MM than gymnasts, long sprinters, non-athletic males and distance runners (P < 0.01). Also, MM was greater in track and field power athletes than in distance runners (P < 0.05). The MM as a percentage of body mass (%MM) ranged from 56.5% in the non-athletic group to 65.1% in the body-builders; body-builders scored higher than basketball players (P < 0.05), distance runners (P < 0.01) and the non-athletic group (P < 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Adipose Tissue↗

Modulation of visual responses in macaque frontal eye field during covert tracking of invisible targets.

The purpose of this study was to investigate the interaction between internal representations of invisible moving targets and visual responses of neurons in frontal eye fields (FEFs). Monkeys were trained to make saccades to the extrapolated position of a target that was temporarily rendered invisible for variable durations as if it had passed behind an occluder. Flashed, task-irrelevant visual probe stimuli were used to study the visual responsiveness of FEF neurons during this task. Probes were flashed at various times and locations during the occlusion interval. Net changes in neuronal activity were obtained by comparing the activity on trials with probes with randomly interleaved trials without any probe. Most neurons showed an increase in firing rate in response to the probe, but some showed a decrease. Both types of responses were enhanced when the invisible target moved toward the receptive field (RF) as compared with trials on which the target moved away from the RF. Some neurons showed a spatial shift in the visual response during the occlusion interval. For cells that were excited by the probe, the shift tended to be correlated with the direction of motion of the target, whereas for cells that were inhibited the shift tended to be in the opposite direction. These results suggest that the role of FEF in predicting invisible target motion includes a sensory/perceptual component.

Adaptation, Physiological↗

A regular period for Saturn's magnetic field that may track its internal rotation.

The rotation rate of a planet is one of its fundamental properties. Saturn's rotation, however, is difficult to determine because there is no solid surface from which to time it, and the alternative 'clock'--the magnetic field--is nearly symmetrically aligned with the rotation axis. Radio emissions, thought to provide a proxy measure of the rotation of the magnetic field, have yielded estimates of the rotation period between 10 h 39 min 22 s and 10 h 45 min 45 s (refs 8-10). Because the period determined from radio measurements exhibits large time variations, even on timescales of months, it has been uncertain whether the radio-emission periodicity coincides with the inner rotation rate of the planet. Here we report magnetic field measurements that revealed a time-stationary magnetic signal with a period of 10 h 47 min 6 s +/- 40 s. The signal appears to be stable in period, amplitude and phase over 14 months of observations, pointing to a close connection with the conductive region inside the planet, although its interpretation as the 'true' inner rotation period is still uncertain.

Journal Article↗

Dosimetric implications of pulmonary macrophage clusters observed within lungs of rats that have inhaled enriched UO2 particles.

Twenty-four Fischer 344 rats were exposed to enriched uranium dioxide (UO2) aerosols to give a mean initial lung burden of 291 +/- 89 (SD) micrograms. Groups of rats were killed at 1, 7, 180, 360, 540, and 720 days post-inhalation (PI). Their lungs were fixed and inflated. Sections cut from all five lung lobes were used to prepare CR-39 neutron-induced 235U fission fragment autoradiographs. A single traverse across a CR-39 autoradiograph of a tissue section, from the left lung of all the rats, was made using a motorized microscopic stage. The traverse was divided into 10 fields. The track counts per field were used to test for homogeneity of track distribution and to assess if there was any tendency for tracks to be related to the peripheral region of the lung. Full raster scans across the entire tissue image were made on left lung autoradiographs from two animals killed at each time point to assess the homogeneity of fission fragment track distribution throughout the entire section. There was no evidence of any temporal change in the proportion of tracks associated with the lung periphery. At all time points PI, the track distribution was significantly nonhomogeneous, suggesting a nonuniform pattern of tissue irradiation from the 234U alpha particles. At time points from 180 to 720 days PI, large clusters of macrophages were observed in some of the sections taken from all five lung lobes. The total number of macrophage clusters increased with time PI. These macrophage clusters produced many 235U fission fragment tracks within the CR-39 autoradiographs.(ABSTRACT TRUNCATED AT 250 WORDS)

Administration, Inhalation↗

A systematic review on ankle injury and ankle sprain in sports.

This article systematically reviews epidemiological studies on sports injury from 1977 to 2005 in which ankle injury was included. A total of 227 studies reporting injury pattern in 70 sports from 38 countries were included. A total of 201,600 patients were included, with 32,509 ankle injuries. Ankle injury information was available from 14,098 patients, with 11 847 ankle sprains. Results show that the ankle was the most common injured body site in 24 of 70 included sports, especially in aeroball, wall climbing, indoor volleyball, mountaineering, netball and field events in track and field. Ankle sprain was the major ankle injury in 33 of 43 sports, especially in Australian football, field hockey, handball, orienteering, scooter and squash. In sports injuries throughout the countries studied, the ankle was the second most common injured body site after the knee, and ankle sprain was the most common type of ankle injury. The incidence of ankle injury and ankle sprain was high in court games and team sports, such as rugby, soccer, volleyball, handball and basketball. This systematic review provides a summary of the epidemiology of ankle injury in sports.

Ankle Injuries↗

Monitoring strength training: neuromuscular and hormonal profile.

PURPOSE: This study investigated changes induced by a single heavy resistance training session on neuromuscular and endocrine systems in trained athletes, using the same exercises for training and testing. METHODS: Five different groups volunteered: track and field male sprinters (MS, N = 6), track and field female sprinters (FS, N = 6), body builders (BB, N = 6), and weight lifters performing low-repetition exercise (WLL, N = 4) and high-repetition exercise (WLH, N = 4). In training, the work performed during half and full squat exercise was monitored for mechanical power output as well as EMG analysis on leg extensor muscles of the subjects belonging to the MS, FS, and BB groups. Just before and immediately after the training session, venous blood samples were obtained for RIA determination of testosterone (T), cortisol (C), lutropin (LH), human prolactin (PRL), and follitropin (FSH) in FS and MS. In the other three groups (BB, WLH, and WLL), the hormonal profile was limited to T and human growth hormone (hGH) only. RESULTS: After training the power developed in full squat demonstrated a statistically significant decrease (P < 0.01) in MS and no changes in FS. The EMG activity remained constant during the training session. Consequently, the EMG/Power ratio increased in both MS and FS, although only in MS a statistical significance was noted (P < 0.05). In MS immediately after the session the levels of C, T, and LH were significantly lower (P < 0.05). No changes were found in FS. In both groups and in BB significant negative correlation was found between changes in T level and EMG/Power ratio in half squat performance. CONCLUSIONS: It is likely that adequate T level may compensate the effect of fatigue in FT fibers by ensuring a better neuromuscular efficiency.

Adult↗

Injury patterns in Scottish heavy athletics.

As interest and participation in the athletics of Scottish-American Highland games has increased throughout the United States, the aim of this study was to define injury patterns and risk factors. Field events of modern track and field evolved in part from the seven events of the "heavy athletics." A retrospective and prospective study of 170 athletes with at least 3 years of experience was carried out over 10 years. There were 729 injuries, 60% of which involved the upper extremities and back. The incidence of injury was 42.9%; there was an injury exposure rate of 0.3 per 40 hours of competition or training. With appropriate instruction, a consistent weight program, and exercise, few injuries were serious.

Adult↗

Catastrophic pediatric sports injuries.

The high school sports of wrestling, gymnastics, ice hockey, baseball, track, and cheerleading should receive closer attention to prevent injury. Safer equipment and sport-specific conditioning should be provided and injuries strictly monitored. Greater attention must also be paid to swimming and diving techniques, and continued observation is needed for heat stroke and heat intolerance in sports such as football, wrestling, basketball, track and field, and cross-country. An increased awareness of commotio cordis in sports other than baseball should include ice hockey, football, track field events, and lacrosse. American football because of the sheer numbers and associated catastrophic injury potential must continue to be monitored at the highest medical levels!

Adolescent↗

A study of changes in the spine in weight lifters and other athletes.

The present study was undertaken in sportsmen of those groups of sports activities where weight training exercises constitute a major part of the training. Two groups consisting of 25 weight-lifters and 25 track and field athletes were studied to find out the effect of sports activities and lifting weights on the spine. 84% weight-lifters and 72% track and field athletes suffered from varying abnormalities. Incidence of backache in 25 weight-lifters was 40% and in 25 track and field athletes 48%. Radiological changes were more common in weight-lifters (84%) than in athletes (72%). Reduction in lumbar lordosis was found in three cases (12%) in both the groups. Obtuse angle deformity of vertebral margins was found in 11 cases (44%) amongst weight-lifters and six cases (24%) amongst athletes. Osteophytic formation was found in six cases (24%) in weight-lifters and four cases (16%) in athletes. Schmorl's node were noticed in five cases (20%) amongst weight-lifters and seven cases (28%) amongst athletes. The incidences of spondylosis and Schmorl's node were found only in those cases who had been doing weight training exercises for more than four years.

Adolescent↗

Dynamic field map estimation using a spiral-in/spiral-out acquisition.

The long readout times of single-shot acquisitions and the high field strengths desired for functional MRI (fMRI) using blood oxygenation level-dependent (BOLD) contrast make functional scans sensitive to magnetic field inhomogeneity. If it is not corrected during image reconstruction, field inhomogeneity can cause geometric distortions in the images when Cartesian k-space trajectories are used or blurring with spiral acquisitions. Many traditional methods to correct for field inhomogeneity distortions rely on a static field map measured with the use of images that are themselves distorted. In this work, we employ a regularized least-squares approach to jointly estimate both the undistorted image and field map at each acquisition using a spiral-in/spiral-out pulse sequence. Simulation and phantom studies show that this method is accurate and stable over a time series. Human functional studies show that the jointly estimated field map may be more accurate than standard field map estimates in the presence of respiration-induced phase oscillations, leading to better detection of functional activation. The proposed method measures a dynamic field map that accurately tracks magnetic field drift and respiration-induced phase oscillations during the course of a functional study.

Brain↗

Visual loss and performance in blind athletes.

We examined the relationship between visual loss and athletic performance and evaluated the visual classification system used in the 1988 United States Association of Blind Athletes (USABA) Summer Games. Athletes were asked about their age, sex, training, years of participation in organized competition, age at onset of blindness and were given an ophthalmologic exam that included Snellen acuity, contrast sensitivity, and visual fields. In the speed track events, visual class,* sex, age, hours of training, and years participating were found to have a positive correlation with performance. Visual class and sex were significant predictors of performance in the intermediate distance events; visual class was the only significant predictor of performance in the long distance events. Visual class, sex, age, and hours of training were correlated with performance in the track and field (throwing) events. Weightlifting performance was influenced by age and sex. The most consistent predictor of performance in the swimming events was the number of hours training per week. Our results indicate that the current classification system for visual loss is useful for grouping athletes for competition.

Blindness↗