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PubMedDate not supplied

Thoracic splenosis. Diagnosis of a case by fine needle aspiration cytology.

Fine needle aspiration cytology was used to study chest wall nodules in a patient who presented with fever, cough, pleuritic chest pain and cytomegalovirus infection and who had a previous history of abdominal trauma. The finding of splenic red pulp and white pulp in the aspirate, combined with the results of a radionucleotide liver-spleen scan, led to a diagnosis of thoracic splenosis, a relatively rare condition. Splenosis is thought to result from transplantation of splenic tissue after trauma and may provide some added protection against certain infectious conditions, both of which were present in this case.

Biopsy, Needle↗
PubMed1989

Splenic function after splenectomy for trauma. Role of autotransplantation and splenosis.

Follow-up of patients treated for severe trauma to the spleen, with autotransplantation (20 cases) or splenectomy (21 cases) included hepatic and splenic scintigraphy, intracutaneous skin testing with seven recall antigens and hematologic studies (red and white blood count, Howell-Jolly bodies, erythrocyte morphology, immunoglobulins, complements). In all reimplantation cases splenic tissue was scintigraphically demonstrated. After removal of the spleen due to severe traumatic ruptures the incidence of splenosis was 66%. Good clearance function in all reimplantation and splenosis cases was demonstrated by Howell-Jolly bodies and erythrocyte morphology. Autotransplantation of splenic tissue is a simple and safe procedure, without serious complications. As yet, however, there is no proof that it provides adequate resistance to infections. Reimplantation, therefore, should be performed only if spleen-preserving procedures are not feasible.

Adolescent↗
PubMed1988

Splenosis: report of a case and review of the literature.

Splenosis is the autotransplantation of splenic tissue that usually follows traumatic rupture of the spleen. These splenic implants may be located anywhere within the peritoneal cavity. Although a relatively rare entity, when present these implants may mimic endometriosis or even metastatic carcinoma. As splenosis may compensate in part for the asplenic state, it is recommended that these splenic implants not be removed. It is important to correctly diagnose this condition to avoid unnecessary therapy. Diagnosis and management are discussed as well as a review of the literature.

Adult↗
PubMed1987

[Splenosis: an unrecognized cause of pelvic pain].

A case of painful pelvic splenosis is reported. This diagnosis concerns a patient suffering from pelvic pain who had had a splenectomy done thirteen years earlier. Two complementary examinations allowed us to make a precise pre-operatory diagnosis. The differential diagnoses are listed and endometriosis in particular. The authors think that the nodules of splenosis are probably a defense against infections affecting "splenic" patients. Consequently, the removal only of symptomatic ectopic splenic tissue is indicated.

Adult↗
PubMed1974

Abdominal splenosis.

Abdominal splenosis was an incidental finding at laparotomy for acute appendicitis in a 39-year-old man who had had splenectomy for traumatic rupture of the spleen nine years previously. Similar cases of abdominal and intrathoracic splenosis are reviewed.

Adult↗
PubMed1982

Splenosis: CT demonstration of heterotopic autotransplantation of splenic tissue.

Splenosis is a rare condition manifested by heterotopic autotransplantation of splenic tissue. A case of splenosis initially diagnosed with computed tomography (CT) and confirmed with radionuclide imaging is presented. This condition can be confused with other causes of peritoneal based masses and must be differentiated from them to assure optimum patient care. The clinical, pathologic, and CT features of this condition are briefly reviewed.

Abdominal Neoplasms↗
PubMed1993

[Splenosis].

Four patients where during childhood splenectomy was performed on account of a traumatic indication were after 9-12 years subjected to sonographic and scintigraphic examination focused on possible evidence of splenosis. In one case asymptomatic splenosis was detected by scintigraphy.

Adolescent↗
PubMed2004

Hepatic splenosis misinterpreted as hepatocellular carcinoma in cirrhotic patients referred for liver transplantation: report of two cases.

Liver transplantation is one of the main therapeutic options for hepatocellular carcinoma (HCC) occurring in cirrhotic patients; an accurate diagnosis and staging of this cancer is crucial to selecting the candidates for this treatment. Although the best diagnostic strategy is debated, the guidelines proposed by the European Association for the Study of the Liver (EASL) are used by many centers. We report 2 cases of cirrhotic patients with hepatic splenosis, a rare condition that may be misinterpreted as HCC. In conclusion, the application of the EASL guidelines in the first case would have led to an incorrect staging of the cancer and in the second case would have led to a false diagnosis of HCC.

Carcinoma, Hepatocellular↗
PubMedDate not supplied

Intrahepatic splenosis: imaging features.

We report a patient who presented with asymptomatic focal liver lesions and in whom a diagnosis of intrahepatic splenosis was made. This rare condition mostly occurs in patients who previously underwent splenic trauma or surgery. Magnetic resonance imaging (MRI) characteristics suggesting this diagnosis are described. The lesions were mainly hypointense on T1- and hyperintense on T2-weighted images. After administration of small iron oxide particles (SPIO-Endorem), the lesions remained slightly hyperintense relative to the hypointense liver parenchyma but showed a 50% loss in signal intensity. Knowledge of these MRI characteristics may avoid the use of surgical interventions to arrive at the correct diagnosis of these rare liver lesions.

Humans↗
PubMed2003

Splenosis presenting with adnexal mass: a case report.

CASE REPORT: A 21-year-old woman presenting with low abdominal discomfort, dysmenorrhoea and pelvic mass was misdiagnosed as endometriosis. She had post-traumatic splenic rupture and laparotomy history. RESULTS. Pelvic splenosis was diagnosed at laparotomy. Pelvic mass was removed and the other implants were left.

Adnexal Diseases↗
PubMed2005

Intrathoracic splenosis.

Intrathoracic splenosis is a rare condition involving autotransplantation of the splenic tissue into the pleural cavity. It is typically a result of diaphragmatic and splenic rupture after blunt or penetrating abdominal trauma. The diagnosis is usually determined by surgical biopsy of an incidental asymptomatic mass on a radiograph or computed tomography. The process is benign and can be generally followed with serial chest radiographs. We herein discuss a 34-year-old male who presented with sharp chest pains.

Adult↗
PubMed1999

Noninvasive methods of diagnosing thoracic splenosis.

Thoracic splenosis is a rare condition resulting from concomitant rupture of the spleen and left hemidiaphragm, with autotransplantation of splenic tissue into the left hemithorax. It is usually an incidental finding on chest plain film or computed tomogram and is rarely diagnosed without biopsy or operation. A history of old splenic trauma and findings of left-sided, pleural-based nodules should indicate the diagnosis, which can be confirmed with nuclear medicine studies.

Aged↗
PubMed1999

Splenosis mimicking metastases from breast carcinoma.

The case history is presented of a patient with breast cancer who was extensively investigated for presumed hepatic metastases, which were finally diagnosed as splenosis, the heterotopic autotransplantation of splenic tissue after traumatic rupture of the spleen. This case history highlights the importance of obtaining a pathological diagnosis prior to labelling a patient as having metastatic disease. This is especially important for patients who have an unusual pattern or appearance of metastases or for whom the risk of metastatic disease is presumed to be minimal.

Breast Neoplasms↗
PubMed2003

Extramedullary hematopoietic proliferations, extraosseous plasmacytomas, and ectopic splenic implants (splenosis).

Hematopoietic proliferations are well known to present ectopically outside the bone marrow, either in benign or malignant form. As such, they present a distinct problem with respect to morphologic interpretation because of their uncommonality in extramedullary sites and their capacity to simulate other lesions histologically. This review considers extramedullary myeloid tumors ("granulocytic sarcoma," "erythroblastic sarcoma," "megakaryocytic sarcoma"), tumefactive extramedullary hematopoiesis, and the peculiar condition known as "splenosis," with consideration of their clinical, microscopic, and cytohistochemical chararacteristics.

Biomarkers, Tumor↗