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At least 109 records · Page 6Linked to original sources
PubMed1992

A manufacturing system for contoured foam cushions.

The design, application and evaluation of a specialized, personal computer-based manufacturing system for contouring foam cushions is presented. The topics discussed include both the hardware configuration and the software design. The target applications of this device are local or centralized fabrication of custom-contoured seat cushions. Although the technologies used for the development and implementation of this system are not new, using a personal-computer-based (PC) controller in place of a stand-alone numerically controlled (NC) motion controller significantly reduced the cost associated with this component. Further reductions in cost resulted from an optimization of the mechanical configuration for the dedicated task of carving foam cushions.

Computer-Aided Design↗
PubMed2000

[The development of an instrument for testing body water equillibrium in hemodialysis patients].

In order to obtain a real-time and correct test for body water equilibrium in hemodialysis patients, an instrument based on bioimpedance measurement has been developed. The hardware and software design of the instrument was introduced in this paper. The instrument is of safty and good duplicity. Preliminary clinical experiments shows that it can reflect the state of body water with relative high sensitivity.

Adult↗
PubMed1994

Design and application of PDBlib, a C++ macromolecular class library.

PDBlib is an extensible object-oriented class library written in C++ for representing the three-dimensional structure of biological macromolecules. The software design strategy, features of many of the 129 classes currently distributed with the library, and two sample applications which use the library are described. Version 1.0 of the library represents the structural features of proteins, DNA, RNA and complexes thereof, at a level of detail on a par with that which can be parsed from a Protein Data Bank (PDB) entry. However, the memory-resident representation of the macromolecule is independent of the PDB entry and can be obtained from other sources, e.g. relational and object-oriented databases. PDBlib classes are organized into four categories: (i) classes that model the macromolecule; (ii) classes that enhance the extensibility of the library; (iii) classes that provide navigation facilities of the object-oriented macromolecular structure representation; and (iv) a class that loads a PDB file into the memory-resident object-oriented representation. A number of general-purpose procedures that return features of this representation and that are relevant to all biological disciplines are included in (i). The library has been used to develop PDBtool, a prototype structure verification tool, and PDBview, a structure rendering tool that requires no specialized graphics hardware and software. Current work centers on making the macromolecular structures represented by PDBlib persistent using a commercial object-oriented database and providing an additional class library, MMQLlib, to query those structures.

Databases, Factual↗
PubMed2002

Design of a cardiac monitor in terms of parameters of QRS complex.

Objective. To design a portable cardiac monitor system based on the available ordinary ECG machine and works on the basis of QRS parameters. Method. The 80196 single chip microcomputer was used as the central microprocessor and real time electrocardiac signal was collected and analyzed [correction of analysized] in the system. Result. Apart from the performance of an ordinary monitor, this machine possesses also the following functions: arrhythmia analysis, HRV analysis, alarm, freeze, and record of automatic papering. Convenient in carrying, the system is powered by AC or DC sources. Stability, low power and low cost are emphasized in the hardware design; and modularization method is applied in software design. Conclusion. Popular in usage and low cost made the portable monitor system suitable for use under simple conditions.

Arrhythmias, Cardiac↗
PubMed2004

ProteMiner-SSM: a web server for efficient analysis of similar protein tertiary substructures.

Analysis of protein-ligand interactions is a fundamental issue in drug design. As the detailed and accurate analysis of protein-ligand interactions involves calculation of binding free energy based on thermodynamics and even quantum mechanics, which is highly expensive in terms of computing time, conformational and structural analysis of proteins and ligands has been widely employed as a screening process in computer-aided drug design. In this paper, a web server called ProteMiner-SSM designed for efficient analysis of similar protein tertiary substructures is presented. In one experiment reported in this paper, the web server has been exploited to obtain some clues about a biochemical hypothesis. The main distinction in the software design of the web server is the filtering process incorporated to expedite the analysis. The filtering process extracts the residues located in the caves of the protein tertiary structure for analysis and operates with O(nlogn) time complexity, where n is the number of residues in the protein. In comparison, the alpha-hull algorithm, which is a widely used algorithm in computer graphics for identifying those instances that are on the contour of a three-dimensional object, features O(n2) time complexity. Experimental results show that the filtering process presented in this paper is able to speed up the analysis by a factor ranging from 3.15 to 9.37 times. The ProteMiner-SSM web server can be found at http://proteminer.csie.ntu.edu.tw/. There is a mirror site at http://p4.sbl.bc.sinica.edu.tw/proteminer/.

Binding Sites↗
PubMed2004

Trade-off analysis in the Northern Andes to study the dynamics in agricultural land use.

In this paper we hypothesize that land use change can be induced by non-linearities and thresholds in production systems that impact farmers' decision making. Tradeoffs between environmental and economic indicators is a useful way to represent dynamic properties of agricultural systems. The Tradeoff Analysis (TOA) System is software designed to implement the integrated analysis of tradeoffs in agricultural systems. The TOA methodology is based on spatially explicit econometric simulation models linked to spatially referenced bio-physical simulation models to simulate land use and input decisions. The methodology has been applied for the potato-pasture production system in the Ecuadorian Andes. The land use change literature often describes non-linearity in land use change as a result of sudden changes in the political (e.g. new agricultural policies) or environmental setting (e.g. earthquakes). However, less attention has been paid to the non-linearities in production systems and their consequences for land use change. In this paper, we use the TOA system to study agricultural land use dynamics and to find the underlying processes for non-linearities. Results show that the sources of non-linearities are in the properties of bio-physical processes and in the decision making-process of farmers.

Agriculture↗
PubMed2006

The technical development of crystals and oscillators in China and their market situation.

In recent years the manufacture of and demand for crystals and oscillators in China have been increasing quickly because of the development of industries, communications, science, transportation, and electronic techniques. This paper introduces the manufacture, research, and characteristics of the technical development of crystals and oscillators in the last ten years in China. To meet the demand from industry, science, and other markets, the number of companies that produce and research crystals and oscillators has increased from several to more than 300 in the last 20 years. Manufacturing technology and equipment have also improved. For marketing and technical reasons, more than 75% of the companies manufacture mainly 49 micro, 49 micros, and microm crystals. Now more and more companies plan to build production lines to make cold-weld crystals and other precision crystals, and at least two companies have already built their production lines. Most of the precision crystals are AT-cut but some are SC-cut. Integrated TCXOs and DTCXOs have been made by different companies, and the frequency-temperature stability of them is from +/- 2 ppm to +/- 0.5 ppm in a wide temperature range. Specifications of some OCXOs are almost the same as those of foreign OCXOs. The main design techniques in China are experimental. However, in recent years, specially designed software has been developed for oscillator design, and advanced instrumentation and equipment are used. The market situation for crystals and oscillators has increased.

Journal Article↗
PubMed1992

Analysis of beat-to-beat cardiovascular hemodynamic variables obtained from long-term biotelemetry.

Manual methods of large volume data storage, retrieval, and analysis are difficult, time consuming, and present numerous opportunities for calculation errors. We have designed and implemented a comprehensive computer-based system for performing these functions. Development of this system was necessary since left ventricular (LV) blood pressure and two regional LV wall thickness measurements were obtained during long-term extracorporeal biotelemetry of miniswine for 24-h periods. During a single recording period over 100,000 individual cardiac cycles were recorded on analog tape and later analysed for determination of global myocardial oxygen demand and regional myocardial function. In addition, custom designed software was developed to determine the extent and duration of myocardial dysfunction. Batch file commands enabled the customized software to operate without prompting by the user thus optimizing the time usage of the computer, and the computer based data acquisition and analysis system. Although this system was designed specifically for analysing cardiovascular hemodynamic variables, it is flexible and can be applied to other experimental applications.

Analog-Digital Conversion↗
PubMed2001

American Academy of Pediatrics: Task Force on Medical Informatics. Special requirements for electronic medical record systems in pediatrics.

Electronic medical record (EMR) systems, which are usually designed for adult care, must perform certain functions to be useful in pediatric care. This statement outlines these functions (eg, immunization tracking and pediatric dosing calculations) to assist vendors and standards organizations with software design for pediatric systems. The description of these functions should also provide pediatricians with a set of requirements or desirable features to use when evaluating EMR systems. Particular attention is paid to special aspects of pediatric clinical care and privacy issues unique to pediatrics.

Child↗
PubMed1998

Integrating task and data flow analyses using the pentanalysis technique.

Pentanalysis is a new method that allows the integration of task analysis with data flow analysis. This is novel and desirable as it provides one means by which a human-computer interaction orientated method can provide input to the requirements specification stage of the software life cycle. It bridges the gulf that exists between this stage and one major representation, data flow diagrams, commonly used in the software design stage. The method is described and a worked example is provided to illustrate it.

Humans↗
PubMedDate not supplied

Redesigning a risk-management process for tracking injuries.

The changing responsibilities of registered nurses are challenging even the most dedicated professionals. To survive within her newly-defined roles, one nurse used a total quality improvement model to understand, analyze, and improve a medical center's system for tracking inpatient injuries. This process led to the drafting of an original software design that implemented a nursing informatics tracking system. It has resulted in significant savings of time and money and has far surpassed the accuracy, efficiency, and scope of the previous method. This article presents an overview of the design process.

Accidental Falls↗
PubMed2005

GeMS: an advanced software package for designing synthetic genes.

A user-friendly, advanced software package for gene design is described. The software comprises an integrated suite of programs-also provided as stand-alone tools-that automatically performs the following tasks in gene design: restriction site prediction, codon optimization for any expression host, restriction site inclusion and exclusion, separation of long sequences into synthesizable fragments, T(m) and stem-loop determinations, optimal oligonucleotide component design and design verification/error-checking. The output is a complete design report and a list of optimized oligonucleotides to be prepared for subsequent gene synthesis. The user interface accommodates both inexperienced and experienced users. For inexperienced users, explanatory notes are provided such that detailed instructions are not necessary; for experienced users, a streamlined interface is provided without such notes. The software has been extensively tested in the design and successful synthesis of over 400 kb of genes, many of which exceeded 5 kb in length.

Base Sequence↗
PubMedDate not supplied

Lessons learned from a pilot implementation of the UMLS information sources map.

OBJECTIVE: To explore the software design issues involved in implementing an operational information sources map (ISM) knowledge base (KB) and system of navigational tools that can help medical users access network-based information sources relevant to a biomedical question. DESIGN: A pilot biomedical ISM KB and associated client-server software (ISM/Explorer) have been developed to help students, clinicians, researchers, and staff access network-based information sources, as part of the National Library of Medicine's (NLM) multi-institutional Unified Medical Language System (UMLS) project. The system allows the user to specify and constrain a search for a biomedical question of interest. The system then returns a list of sources matching the search. At this point the user may request 1) further information about a source, 2) that the list of sources be regrouped by different criteria to allow the user to get a better overall appreciation of the set of retrieved sources as a whole, or 3) automatic connection to a source. RESULTS: The pilot system operates in client-server mode and currently contains coded information for 121 sources. It is in routine use from approximately 40 workstations at the Yale School of Medicine. The lessons that have been learned are that: 1) it is important to make access to different versions of a source as seamless as possible, 2) achieving seamless, cross-platform access to heterogeneous sources is difficult, 3) significant differences exist between coding the subject content of an electronic information resource versus that of an article or a book, 4) customizing the ISM to multiple institutions entails significant complexities, and 5) there are many design trade-offs between specifying searches and viewing sets of retrieved sources that must be taken into consideration. CONCLUSION: An ISM KB and navigational tools have been constructed. In the process, much has been learned about the complexities of development and evaluation in this new environment, which are different from those for Gopher, wide area information servers (WAIS), World-Wide-Web (WWW), and MOSAIC resources.

Abstracting and Indexing↗
PubMed2000

DbMap: improving database interoperability issues in medical software using a simple, Java-Xml based solution.

In medical software development, the use of databases plays a central role. However, most of the databases have heterogeneous encoding and data models. To deal with these variations in the application code directly is error-prone and reduces the potential reuse of the produced software. Several approaches to overcome these limitations have been proposed in the medical database literature, which will be presented. We present a simple solution, based on a Java library, and a central Metadata description file in XML. This development approach presents several benefits in software design and development cycles, the main one being the simplicity in maintenance.

Databases as Topic↗
PubMed2003

[Validation of a tool to measure pelvic and spinal parameters of sagittal balance].

PURPOSE OF THE STUDY: Parameters determining sagittal balance are essential for optimal analysis and treatment of many spinal disorders. The purpose of this work was to validate a software designed to measure the principal parameters involved in sagittal balance of the spine. MATERIAL AND METHODS: Six parameters (lumbar lordosis, thoracic kyphosis, sagittal tilt at T9, pelvic index, pelvic tilt, slope of the sacrum) were measured on lateral views of the spine from 100 healthy volunteers free of any spinal disease. Two measurement techniques were used: manual measurement and automatic computerized measurement with this software. We hypothesized that manual measures could be accepted as reference values because they are currently the most widely used and because the computerized measurements were obtained using digitalized images that may have modified interpretation. The software was therefore validated by comparing the angles measured manually with the computer output. Inter- and intraobserver coefficients of variation were calculated for the two measurement techniques. One operator performed both series of measurements (manual and computerized). Two other operators preformed two series of independent measures using one of the measurement techniques. Finally, two new operators performed a complete series of measurements using both measurement techniques. Comparisons were performed with the t test for paired variables with calculation of the coefficients of correlation. Intraclass coefficients of correlation were determined for inter- and intra-observer variability. RESULTS: There was an excellent correlation between the manual measurements and the computerized measurements with intra-class coefficients of correlation varying from 0.82 to 0.96. Inter- and intra-observer variabilities were comparable for the two measurement techniques used to determine thoracic kyphosis, lumbar lordosis, pelvic index, pelvic tilt, and slope of the sacrum. Inter- and intra-observer variability was lower when the sagittal tilt was measured with the software specially designed. CONCLUSION: This comparison between two techniques for measuring pelvic and spinal parameters of sagittal balance of the spine demonstrated a good correlation between manual and the computerized measurements obtained with the software to be evaluated. Computer-assisted measurements not only provided a saving in time but also minimized inter- and intra-observer variability for the estimation of certain parameters.

Adult↗
PubMedDate not supplied

Rigorous, rapid, reliable and qualitative? Computing in qualitative method.

OBJECTIVE: To explore whether qualitative methods are problematic and persuasive in health education research. METHOD: Explored this problem through the 3 goals of rigor, rapidity, and reliability and their special meanings in qualitative analysis. RESULTS: For each, contributions of qualitative computing software are identified and their effects assessed. CONCLUSION: Qualitative researchers are assisted by software tools in pursuit of each of these goals, but in each area there is a need for software design to address the tasks of research where rigor, rapidity, and reliability are paramount requirements.

Australia↗
PubMedDate not supplied

Design methods and architectural issues of integrated medical image data base systems.

The past 20 years have seen tremendous changes in medical imaging techniques. New modalities and protocols are expanding the available digital image data at a rapid rate. Yet a framework for gathering, managing, and using multimodal image information is an integrated database environment is missing. The purpose of this paper is to present the experience of implementing an integrated medical image database system at UCSF. We discuss the general system architecture, software design methods, and specific database tools and illustrate them with application examples. Two immediate issues conforming the building of medical image database systems are: lack of supporting infrastructure and inability to index images by contest. To circumvent these problems, the evolutionary medical image database system being implemented at UCSF is based on a three-tiered client-server architecture: client medical workstations, database application servers, and a hospital-integrated picture archiving and communication system (HIP-PACS). The approach used to integrate content-based retrieval and knowledge base techniques within the existing HI-PACS to make the whole database system useful in medicine.

Adult↗