Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Program Accessibility”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 109 records · Page 6Linked to original sources
PubMed1995

Access to hospice programs in end-stage dementia: a national survey of hospice programs.

OBJECTIVE: Because care of end-stage dementia is a significant clinical problem for which alternative modes of care are needed, this study examined the extent to which hospice programs served dementia patients. DESIGN: A survey of 1694 hospices with 1184 respondents (70%). PATIENTS: Identified patients had end-stage dementia, with no concurrent terminal illness. MEASURE: The proportion of end-stage dementia patients in hospice was measured. RESULTS: Fewer than 1% of hospice patients had a primary diagnosis of end-stage dementia, and only 21% of the hospices served such patients. However, 7% of hospice patients had a dementia secondary to another terminal illness, and 56% of the hospices served such patients. For 80% of the hospices, the major problem in serving dementia patients was the difficulty in predicting their survival time. A higher proportion of for-profit hospices served dementia patients (42%) compared with non-profit programs (22%) or public programs (15%), P < .001. CONCLUSIONS: A national survey of hospices revealed that few patients with primary dementia are currently treated by these programs, unless they have other terminal illnesses. An inability to predict survival was the major reason offered to explain this phenomenon. The higher percentage of patients with secondary dementia in hospice suggests that dementia per se does not make hospices care unfeasible. Similarly, the high proportion of for-profit hospices that enrolled patients whose dementia was primary implies the fiscal feasibility of providing hospice care for these patients. Further study is needed concerning the determinants of survival time in end-stage dementia.

Dementia↗
PubMed1985

The SEQANAL and SEQTALK programs: a new method of access to high-resolution nucleotide sequence comparison and analysis programs from a remote laboratory mini- or microcomputer.

A new method of access has been devised for biologists requiring the use of computer programs offering high-resolution analysis and comparison of nucleotide sequence data. The strategy involves the development of a pair of computer programs, called SEQANAL and SEQTALK, designed to operate in tandem. SEQANAL is a large and complex program intended to be used to discover regions of internal repeats and dyad symmetries within one sequence, or regions of homology, complementarity or optimal alignment between two sequences. Three algorithms are supported: those of Staden (1977, 1978); of Korn et al. (1977); Queen and Korn (1980); and the newly-described exhaustive tree-searching algorithm of Burnett et al. (1985, 1986). The SEQTALK program is a small, portable, interactive, front-end program with which the user can specify the instructions to control the SEQANAL program. Together, the SEQANAL and SEQTALK programs permit analyses to be performed at a remote facility on a mainframe computer under the complete control of a distant user equipped with minimal computing facilities, and without needing networking facilities.

Algorithms↗
PubMed1985

Design of a limited-access facility and safety program for a genetic toxicology laboratory.

A limited-access facility has been designed as a result of the need for laboratories for testing hazardous materials found in the environment. The facility design features include room air flow and filtration, hood types, sink design and placement, design of countertops, type of flooring and wall sealant, and traffic flow within the laboratories. These laboratories required the diversity to handle weighing of stock hazardous materials, preparation and handling of aliquots, maintenance of dosed animals as well as sterile conditions required for tissue culture and continuous cell culture methods. A safety and health program was also developed which included specific dress (e.g., scrub suit, TYVEK jumpsuit, gloves, safety glasses and safety shoes), safety advisory group, safety response group, medical monitoring program and training of current and new staff members. The design and use of the facility are continuously reevaluated and changes are made as necessitated by either research needs or improved safety methods.

Accident Prevention↗
PubMed1994

A quality improvement program for hemodialysis vascular access.

The effective delivery of dialysis requires repeated reliable access to the central circulation capable of providing rapid extracorporeal blood flow. Unfortunately, this access to the circulation continues to be the "weak link" in the effective delivery of long-term hemodialysis therapy. This will likely become an even greater problem in the future as increasing numbers of patients with limited access sites secondary to advanced age and atherosclerosis enter the end-stage renal program. Therefore, the preservation of these limited vascular access sites is imperative. Vascular access thrombosis is the leading cause of graft loss and venous stenosis is the major cause of graft thrombosis. Early detection of venous stenosis through careful inspection of the graft combined with measurements of venous outflow pressure and urea recirculation can identify venous access stenosis. Identification of these lesions combined with preemptive repair improves dialysis efficiency and preserves vascular access. When these techniques are used, a dramatic impact on dialysis fistula patency and function can be seen.

Arteriovenous Shunt, Surgical↗
PubMed2025

E2F1 induces a G0-G1 reentry transcriptional program without changing chromatin accessibility.

Quiescent cells actively repress cell-cycle genes via chromatin-based mechanisms to maintain a non-dividing state, yet remain poised to reenter upon stimulation. E2F1, a canonical activator of cell-cycle genes, is sufficient to induce reentry from quiescence, but how it overcomes chromatin-mediated repression remains unclear. Here, we show that inducible E2F1 expression triggers exit from quiescence and progression through the cycle without changes in chromatin accessibility, by harnessing regulatory elements with limited, pre-existing accessibility. Using time-resolved transcriptomics, we demonstrate that E2F1 induces an accelerated transcriptional program compared to serum. Unlike serum, which triggers broad chromatin remodeling, E2F1-induced activation occurs in a context of limited accessibility. ChIP-seq reveals that E2F1 directly binds target sites in quiescent cells to upregulate canonical genes. Biochemical reconstitution shows that E2F1 binds nucleosomes and accesses internal E2F sites within histone-wrapped DNA. These findings suggest that E2F1 can engage nucleosome-associated DNA and initiate transcription without major chromatin reorganization, redefining transcription factor-chromatin dynamics during cell fate transitions and establishing E2F1 as a potent regulator of cell-cycle reentry.

Journal Article↗
PubMed1991

Program to increase the accessibility of screening mammography--Rhode Island, 1987-1988.

The Rhode Island Department of Health's (RIDH) Breast Cancer Screening Program (RIBCSP) was initiated in 1987; it includes a broad promotional effort targeting women and physicians, a strong quality-assurance program, reductions in the cost of the breast cancer screening examination, and a telephone appointment and tracking system for screening examinations and follow-up care. This report describes and summarizes an evaluation of the RIBCSP.

Adult↗
PubMed1990

Hearing access 2000. Increasing awareness of the hearing impaired.

Because 90% of all institutionalized elderly have a hearing impairment, nurses in long-term care facilities need to improve the care of the hearing impaired patient and contribute to increasing communication access. The purpose of the Hearing Access 2000 program is to make public facilities more accessible by increasing awareness of the needs of the hearing impaired. Implementation of the program includes an inventory of hearing aids, staff in-service programs, use of assistive devices, otoscopic examinations, cerumen removal protocol, and the use of tent cards, buttons, and posters.

Aged↗
PubMedDate not supplied

The question of access.

Explore the source record for details and available documents.

Contraception Behavior↗
PubMed1989

Nonfinancial barriers to prenatal care.

This article focused on nonfinancial barriers to prenatal care and pointed out that these barriers cannot be ignored if access to care is to be improved. The strategies suggested by the Consensus Conferences for reducing these barriers provide abundant opportunities for all professionals, and the implications for health policy formulated by the Conferences provide direction for eventually eliminating the barriers. It will take a combination of professional, political and public will to make this happen.

Adolescent↗
PubMedDate not supplied

[Hormonal contraception in 46 public family clinics in Rome].

This study investigates the role of 46 public Consultori of Rome, as far as the hormonal contraception with "pill', the most common contraceptive method used by roman women, is concerned. With a series of phone calls, a hypothetic potential customer asked for an appointment directly with the gynaecologist for getting adviced to use "pill" for the first time. The results show that, although the wait for the first appointment directly the gynaecologist is not long (11,3 days as an average), it is very difficult to get it and this was possible only in 12 cases out of 46. We have noted that the first appointment for "pill" was offered with no-medical personnel, like social assistants, sanitary assistants or midwives, in most 16 of cases, and that in a significant number of Consultori was not possible to obtain an appointment whatever. In public Consultory of Rome we have found a different attitude in giving appointment to women for contraception with pill, even inside the same USL (Local Sanitary Unit, the basic structure of public health in Italy, in which Consultori have the role of prevention and promotion of maternity and tutelage of infancy). From this study the need emerges of uniformity in the attitude of Consultori staff in managing the customers, in order to avoid that women, finding so many difficulties, give up referring to these public structure for beginning contraception and choose private professionals or decide not to use the "pill".

Appointments and Schedules↗