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PubMed2005

[Shame and social anxiety in anorexia and bulimia nervosa].

OBJECTIVES: The importance of shame for the understanding of eating disorders has been well-known for a long time, but only few empirical studies exist to date on this aspect. Particularly the sense of self-esteem and external appearance have been attributed a major influence in the emergence of shame. Since social anxiety has increasingly been considered to be a factor in recent discussions related to eating disorders, and shame is a primary symptom of social phobia and of social anxiety in general, the present study focuses on shame and social anxiety in anorexia and bulimia, as compared to other clinical disorders. Another research question is the extent to which the prevalence of shame in eating disorders is influenced by self-esteem, attitudes about appearance and social anxiety. METHODS: The sample consists of 104 (female) patients, comprising 26 patients, respectively, with anorexia nervosa, bulimia nervosa, anxiety disorders and depression. The various variables were recorded with the Internalized Shame Scale (ISS), the Social Interaction Anxiety Scale (SIAS), the Social Phobia Scale (SPS), the Appearance Attitude Scale (AAS) and the Social Autonomous Self-Esteem Scale (SAS). RESULTS: Patients with anorexia and bulimia nervosa have higher scores in internalized global shame than patients with anxiety disorders and depressions. In contrast to anorectic patients, however, patients with bulimia also have higher scores than the other two groups in the area of social performance anxiety; they also differ significantly from the anxiety disorders in terms of interaction anxiety. In the multiple regression analysis of the patients with eating disorders, self-esteem, performance anxiety and perfectionism with regard to appearance prove to be predictors of the affect of shame. DISCUSSION: The findings indicate that not just shame, but also social anxiety, should be regarded as important influencing factors, especially in the case of bulimia nervosa. The question remains as to what extent social anxiety is a result of shame being projected onto the body. For therapeutic considerations, it seems advisable to work on the affect of shame and also include the aspect of social anxiety in focused therapy strategies.

Adolescent↗
PubMed1977

Further relationships between IPAT anxiety scale performance and infantile feeding experiences.

First-year psychology students who either had been breast fed for up to 3 months or never breast fed scored significantly higher on the IPAT Anxiety Scale than those breast fed for longer periods of time. There were no breast feeding effects on the Eysenck Personality Inventory, although females obtained significantly higher neuroticism scores than men. By extending a previous finding these results indicated the need for more data in this area.

Adult↗
PubMed1993

[Drugs for stress].

Speaking of "drugs of stress" is difficult because stress is not a so precise concept. Moreover, the target is not simply the correction of physiological responses to a stimulus, but is the treatment of pathologies which are directly related with stress: post-traumatic stress disorders (PTSD) and performance anxiety. Drug treatment of PTSD is not well codified, even if phenelzine and amitriptyline are, at least relatively, effective medicines. Beta-blockers remain today the main drugs for performance anxiety. Studies about the utility of carbamazepine and clonidine in these disorders are few. Experimental works upon the action of tianeptine on hippocampus cells lead to interesting results. The place of benzodiazepines and neuroleptics is still controversial.

Anxiety Disorders↗
PubMed2006

Etiological factors of unconsummated marriage.

Normal erectile function is subjected to the influence of psychological, hormonal, neurological, vascular and cavernosal factors. Unconsummated marriage is a common medical and social problem in andrology clinics in conservative communities. However, its etiological factors remain unclear. This work aimed to define the probable etiology of unconsummated marriage. A total of 191 patients were evaluated through history taking, constructed questionnaire, educational settings, clinical examination, lab investigation, imaging procedures and other measures. Psychogenic factors were the cause in 74.4% of the investigated patients. Performance anxiety was the cause in 52.9%, and in 21.5% other psychological distresses were responsible. Organic causes represent 7.3%, vaginismus 8.4%, premature ejaculation 3.1% and cases with undetermined etiology were 6.8%. In conclusion, performance anxiety was revealed to be the main contributor. However, other psychogenic, organic and social factors represent sizable etiological factors.

Adolescent↗
PubMed2006

The effects of immediate forewarning of test difficulty on test performance.

Whereas prior research has demonstrated that warning students of an exam's difficulty well in advance of the exam enhances performance, the current research demonstrated the effect of such forewarning immediately before examination administration. Moments before taking an examination in a laboratory environment, participants were either (a) informed that the examination would be difficult, (b) informed that the examination would be easy, or (c) not given any information about the exam's ostensible difficulty. Participants of low trait anxiety performed better when told the exam would be difficult than when told that the exam would be easy. Conversely, participants of high trait anxiety performed worse when told the exam would be difficult than they did when told the exam would be easy or when provided with no such information. Implications and directions for future research are discussed.

Anxiety↗
PubMed2003

NMDA-receptor antagonism via dextromethorphan and ifenprodil modulates graded anxiety test performance of C57BL/6 mice.

The majority of N-methyl-D-aspartate receptors (NMDA-R) in the adult forebrain are di- or triheteromers composed of NR1, NR2A and NR2B subunits. Subunit non-selective NMDA-R antagonists produce anxiolytic-like effects together with motor and sensory side-effects. The graded anxiety test (GAT), permits the within-task distinction of drug effects on anxiety from those on activity and perception. By testing NMDA-R subunit selective agents in the GAT it might be possible to determine whether their effects on anxiety, activity and perception are interrelated, and whether separate NMDA-R subtypes are involved. Dextromethorphan (weakly NR2A-selective) (10 and 30 mg/kg, i.p.) and ifenprodil (highly NR2B-selective) (1, 3 and 5 mg/kg, i.p.) were tested in the GAT. Both drugs failed to induce anxiolysis devoid of side-effects. However, the 10 mg/kg dose of dextromethorpan showed an anxiolytic, whereas the 30 mg/kg dose showed an anxiogenic, behavioral profile. Since the selective blockade of the NR2B subunit by ifenprodil had no clear anxiolytic effect, the anxiolytic potential of NMDA subunit non-selective agents might involve NR2A-containing receptors.

Animals↗
PubMed2005

Neural correlates of telling lies: a functional magnetic resonance imaging study at 4 Tesla.

RATIONALE AND OBJECTIVE: Intentional deception (ie, lying) is a complex cognitive act, with important legal, moral, political, and economic implications. Prior studies have identified activation of discrete anterior frontal regions, such as the ventrolateral prefrontal cortex (VLPFC), dorsolateral prefrontal cortex (DLPFC), dorsal medial prefrontal cortex (DMPFC), and anterior cingulate cortex (ACC) during deception. To extend these findings, we used novel real-time functional magnetic resonance imaging (fMRI) technology to simulate a polygraph experience in order to evoke performance anxiety about generating lies, and sought to ascertain the neural correlates of deception. MATERIALS AND METHODS: In this investigational fMRI study done with a 4-T scanner, we examined the neural correlates of lying in 14 healthy adult volunteers while they performed a modified card version of the Guilty Knowledge Test (GKT), with the understanding that their brain activity was being monitored in real time by the investigators conducting the study. The volunteers were instructed to attempt to generate Lies that would not evoke changes in their brain activity, and were told that their performance and brain responses were being closely monitored. RESULTS: Subjects reported performance anxiety during the task. Deceptive responses were specifically associated with activation of the VLPFC, DLPFC, DMPFC, and superior temporal sulcus. DISCUSSION: These findings suggest the involvement of discrete regions of the frontal cortex during lying, and that the neural substrates responsible for cognitive control of behavior may also be engaged during deception.

Adult↗
PubMed1997

Social anxiety and performance in an interpersonal perception task.

The Interpersonal Perception Task-15 videotape served as a criterion measure to test hypotheses about individual differences in interpersonal perception. 160 undergraduates completed the Personal Report of Communication Apprehension Scale, the Shyness and Sociability Scale, and the Interpersonal Perception Task-15. Scores on the Communication Apprehension Scale were negatively correlated with Interpersonal Perception Task-15 scores, as predicted. Scores on the Shyness scale were negatively correlated with scores on the Interpersonal Perception Task-15, while Sociability scale scores were positively correlated. These results underscore the association between social anxiety and interpersonal perception.

Adolescent↗
PubMed1995

Structural equation modeling of risk factors for the development of eating disorder symptoms in female athletes.

Risk factors for the development of eating disorder symptoms in female college athletes were studied using structural equation modeling. Three risk factors: social influence for thinness, athletic performance anxiety, and self-appraisal of athletic achievement, were selected for study. The association of these risk factors and eating disorder symptoms was hypothesized to be mediated by overconcern with body size and shape. The study sample was 98 women recruited from eight sports teams at a major university. Structural equation modeling analysis supported the hypothesized model and cross-validation of the model showed the findings to be stable. The results of this correlational study suggested that eating disorder symptoms in college athletes are significantly influenced by the interaction of sociocultural pressure for thinness, athletic performance anxiety, and negative self-appraisal of athletic achievement. If these risk factors lead to overconcern with body size and shape, then the emergence of an eating disorder is more probable.

Adolescent↗
PubMed1998

[Psychological stress factors in erectile dysfunctions. Causal models and empirical results].

In this paper the role of psychosocial factors in erectile dysfunction is examined in two different ways: (1) Current approaches to the causation of psychogenic erectile dysfunctions are reviewed and discussed. (2) Empirical results from a large unselected sample of sexually dysfunctional men are presented and compared to a sample of functional men. Concerning etiological models the traditional unidimensional dichotomous concepts (psychogenic versus organic) of erectile dysfunction have to be abandoned and replaced by two-dimensional models that are able to take the clinical reality into account that many patients have both significant psychological and organic factors in their disorder. The main causes of psychogenic erectile disorders can be divided into three groups, each belonging to a different phase of time: (i) immediate factors (performance anxiety), (ii) antecedent life events from recent history, (iii) developmental vulnerabilities from childhood and adolescence. The specific interplay as well as the importance of the different groups is different in primary and secondary erectile disorders. The empirical results presented here are based on a sample of 751 patients from our interdisciplinary outpatient unit for sexually dysfunctional men and a group of 55 sexually functional men. Both groups completed a self-developed, multidimensional questionnaire addressing a variety of psychosocial and descriptive factors concerning erectile disorders. The results prove the heterogeneity of patients and their respective erectile problems and show a number of highly significant group differences. The frequent comorbidity of erectile disorders and premature ejaculation and disorders of desire is worth mentioning as well as the high prevalence of depression and the extreme extent of performance anxiety in the patient group. The results are discussed with respect to future treatment strategies. The necessity of combined psychosomatic approaches optimizing the efficacy of all available therapeutic options is particularly stressed.

Adolescent↗
PubMed2000

Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3alpha,5alpha-THP.

Sex differences and estrous cycle variations in anxiolytic-like behaviors and progestin concentrations were examined. Proestrous (n=22), estrous (n=19), diestrous (n=20), and male (n=18) Long-Evans rats were tested in horizontal crossing, open field, elevated plus-maze, emergence, holeboard, social interaction, tailflick, pawlick, and defensive burying tasks. Concentrations of plasma and hippocampal progesterone and 5alpha-pregnan-3alpha-ol-20-one (3alpha,5alpha-THP) were measured by radioimmunoassay in behaviorally tested (proestrus n=11, estrus n=8, diestrus n=9, male n=7) and yoked non-tested rats (proestrus n=11, estrus n=8, diestrus n=10, male n=8). Proestrous females exhibited more anxiolytic-like behavior than all other groups on the elevated plus-maze, social interaction, and defensive burying tasks. Proestrous females had significantly shorter latencies to emerge from a cylinder than did estrous and diestrous females, but not males. Proestrous and estrous females entered significantly more peripheral and total squares in a brightly-lit open field than did males. While proestrous females had a tendency to make more beam breaks than did males in the horizontal crossing task, there were no differences between groups on the holeboard task. There was a tendency for proestrous females to have longer tailflick latencies than diestrous and male rats; however, on the pawlick task there were no differences among the groups. Plasma and central progesterone and 3alpha,5alpha-THP of tested and non-tested rats were not different. Proestrous females had significantly higher plasma and hippocampal progesterone and 3alpha,5alpha-THP levels than all other groups. These data demonstrate that proestrous increases in anxiolytic-like behavior coincide with elevated circulating and hippocampal progestin concentrations.

Animals↗