Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Neoplastic Processes”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 109 records · Page 6Linked to original sources
PubMed2000

[Cardiac tamponade as clinical manifestation of neoplastic process: presentation of 11 cases and review of the literature].

We analyse the clinical presentation of pericardial effusion in patients with malignancy. The diagnostic sensibility of cytology of the pericardial effusion, current management strategies, recurrences and survival are considered. Retrospective single centre study (Fundación Jiménez Díaz). Eleven patients with malignant pericardial effusion (period: 1992-1996). The most frequent symptom was dyspnea (100%); echocardiogram accuracy was 100% and the sensitivity of pericardial cytology 64%. 73% of all effusions were adenocarcinomas (87.5% of the lung). Pericardiocentesis was practised in 73% patients. Survival did not improve when adding radiotherapy, using local sclerotherapy or surgical pericardial windows (pericardiotomy (medium survival of 109 days). Those patients who died did not develop symptoms of hemodynamic clinical emergency. Prognostic of malignant cardiac tamponade is closely related to the extent of disease and its sensitivity to treatment.

Adenocarcinoma↗
PubMed2000

[Testicular feminization--sequelae of chronic neglect of a neoplastic process].

This paper reports on a 56-year-old patient with a history of "testicular feminization syndrome" who was admitted to hospital because of a rapid gain in her abdominal girth (106 cm). A benign cyst was removed laparotomically which, histologically, was equivalent to a cystadenofibroma. Based on this case report, the clinical significance of testicular feminization syndrome and the necessity for gonadectomy due to the risk of growth of a possibly malignant tumor are discussed.

Abdominal Neoplasms↗
PubMed2001

[Molecular-genetic determinants of the neoplastic process and state-of-the-art treatment of patients with uterine leiomyoma].

Present-day evidence on uterine leiomyomata has pointed to progesterone and its receptors as a key factor in the mechanisms of auto- and paracrine influences on tumor development and growth. Treatment was determined by a correlation between tumor size and stage of molecular-genetical disorders. A clinico-genealogical study of familial predisposition to uterine leiomyoma, particularly in patients from accumulated disease families contributed to the potential of early detection of tumor and timely effective correction for preservation of reproductive function.

Adult↗
PubMed2001

[The role of nitric oxide in carcinogenesis and progression of neoplastic processes].

The aim of the review is to outline the current knowledge about the role of nitric oxide in the processes of proliferation and apoptosis in tumor. Special emphasis has been placed on its direct cytotoxic influence on a cell where as a highly active free radical it may compromise different cellular functions. Nitric oxide literature, regarding its role in the pathogenesis of some gynecological and breast cancer has been briefly reviewed.

Animals↗
PubMed2001

[Human papillomavirus and cervical cancer: genetic background of the neoplastic process].

In a 2-year period, 136 HPV positive cytological samples of the cervix uteri were analyzed at the Department of Molecular Pathology, National Institute of Oncology, Hungary. Comparison with the international data obtained from the literature revealed that the Hungarian epidemiological data bore closest resemblance to the European ones except some differences. The HPV18 is rather seldom encountered in this country. Similarly low occurrence was noted only in Japan. However, the 14.1% occurrence rate of HPV58 in Hungary is by far higher than that in any other country in this analysis except Japan where this virus is of similarly high frequency. In Hungary, the incidence of HPV59 is relatively high just like in Central and South America. HPV33 and HPV66 infections occur in a significantly higher number with Hungary than in any of the countries studied. In our study The European type variant of HPV16 (E-V-350G) occurred in 2/10 CIN II-III cases. The authors also compared the various clinico-pathological grouping of HPV types published, and identified several inconsistencies. Viruses considered to have high risk occurred in intact epithelium, CIN I-II-III and carcinoma alike. The general tendency was, however, that certain viruses correlated with specific clinico-pathological entities. At present there is no reason to include the PCR-based HPV typing in the mass screening of cervical cancers. HPV typing and physical state of the virus can reasonable be determined if the cervical cytology is suspect for HPV infection or even control examination after "loop" conisation. Negative cytology completed with negative HPV-DNA test means the lack of cancer risk even in the case of a previously removed CIN or carcinoma. However, a positive HPV test detected after conisation associated with negative cytology finding indicates a risk of 70% of the development of CIN within 2 years.

Carcinoma↗
PubMed2002

[Non-specific changes in the complement system in neoplastic processes].

The study using immunochemical and biological methods was concerned with assaying complement components C1q, C3, C4, and C5, C3 derivatives--C3a and, C3(H2O), C1ing control protein, hemolytic activity (CH50), total proteolytic activity and regulatory immune complexes in sera from patients with cancer of the stomach, breast and ovary, subjects at risk of cancer and healthy donors. Neoplasia was associated with lowered levels of intact C3 and C1ing matched by high concentrations of C3a, C1q and C4. Hemolytic activity (CH50) was increased against the background of relatively higher total proteolytic activity both in healthy subjects and cancer patients. Significant decrease in C1ing concentration may be used as an additional biochemical prognosticator in breast cancer.

Biomarkers, Tumor↗