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Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

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At least 109 records · Page 6Linked to original sources
PubMed1971

Production of artificial "case histories" by using a small computer.

This paper describes a method of producing artificial "case histories" by using probability theory and clinical data from a series of 600 patients with acute abdominal pain. A series of 12 such cases were distributed to clinicians, medical students, medical secretaries and technicians, and members of the general public. For each "case" most clinicians concurred with the intended diagnosis. So did the medical secretaries and technicians; indeed this group were more confident of their chosen diagnoses than were the clinicians.It is suggested that clinicians are concerned to a large extent with the consequences of a diagnosis as well as its accuracy, and are motivated to some degree by a fear of the consequences of failure. They may be justified in adopting this policy, for when "errors" in diagnosis are harshly penalized the clinicians were infinitely more effective than any of the other groups.

Abdomen↗
PubMed1983

Infections in British clinical laboratories 1980-81.

This survey through the Association of Clinical Pathologists was continued and extended for 1980-81, with the help of the Institute of Medical Laboratory Sciences. Hepatitis maintained a low attack rate of 26/100 000 person-years, including only three cases of hepatitis B probably attributable to laboratory work (attack rate 9). Nineteen cases of tuberculosis (attack rate 56) included 14 of probable occupational origin (attack rate 41) half of which involved post-mortem or mortuary work. Thirteen bacterial infections of the bowel (attack rate 38, predominantly shigellosis) involved almost exclusively microbiology MLSOs, with 10 attributed to laboratory work (attack rate 29). The seven other infections included 4 of occupational sepsis in morbid anatomy and post-mortem workers. There appears to be scope for improvement in bacteriological bench techniques particularly at the faeces bench and for reduction in the hazards of tuberculosis and sepsis for morbid anatomy and mortuary workers.

Bacterial Infections↗
PubMed1997

Staff education.

Explore the source record for details and available documents.

Drug Delivery Systems↗
PubMed2006

Technology to improve quality and accountability.

A body of evidence has been accumulated to demonstrate that current practice is not sufficiently safe for several stages of central laboratory testing. In particular, while analytical and perianalytical steps that take place within the laboratory are subjected to quality control procedures, this is not the case for several pre- and post-analytical steps. The ubiquitous application of auto-identification technology seems to represent a valuable tool for reducing error rates. A series of projects in Oxford has attempted to improve processes which support several areas of laboratory medicine, including point-of-care testing, blood transfusion, delivery and interpretation of reports, and support of decision-making by clinicians. The key tools are auto-identification, Internet communication technology, process re-engineering, and knowledge management.

Clinical Laboratory Techniques↗
PubMed1994

Laser safety programs in general surgery.

General surgery represents a speciality where, while any procedure can be performed with lasers, there are no procedures for which the laser is the sine quo non. The general surgeon may perform a variety of procedures with a multitude of laser wavelengths and technologies. Laser safety in general surgery requires a multidisciplinary approach. Effective laser safety requires the oversight of the hospital's "laser usage committee" and "laser safety officer" while providing a workable framework for daily laser use in a variety of clinical scenarios simultaneously. This framework must be user-friendly rather than oppressive. This presentation will describe laser safety at the Rochester General Hospital, a tertiary care, community-based teaching hospital. The safety program incorporates the following components: input to physician credentialing and training, education and in-servicing of nursing and technical personnel, equipment purchase and maintenance, quality assurance, and safety monitoring. The University of Rochester general surgery residency training program mandates laser training during the PGY-2 year. This program stresses the safe use of lasers and provides the basis for graded hands-on experience during the surgical residency. The greatest challenge for laser safety in general surgery centers on the burgeoning field of minimally invasive surgery. Safety assurance must be balanced so as to maintain a safe operating-room environment while ensuring patient safety and the ability to permit the surgery to proceed efficiently. Safety measures for laparoscopic procedures must be sensitive to the needs of the surgical team while not providing confusing signals for the "gallery" observers. This task is critical for the safe operation of lasers in general surgery. Effective laser safety in general surgery requires constant vigilance tempered with sensitivity to the needs of the surgeon and the patient as laser technology and its applications continue to evolve.

Credentialing↗
PubMed1999

Insulin secretion, clearance and sensitivity in black pregnant and non-pregnant women in Harare, Zimbabwe.

OBJECTIVE: To assess whether reported gestational differences in glucose tolerance in Caucasian and Black women could be due to alterations in insulin secretion, clearance or sensitivity. DESIGN: Cross sectional survey. SETTING: Antenatal Clinic, Harare; Department of Medical Laboratory Sciences, University of Zimbabwe. SUBJECTS: 90 healthy women in all the trimesters of pregnancy and 30 healthy non-pregnant women of reproductive age. MAIN OUTCOME MEASURES: Fasting (basal) plasma insulin, C-peptide and glucose concentration. Fasting plasma C-peptide, C-peptide to insulin ratio and glucose to insulin ratio were used as indices of insulin secretion, hepatic insulin clearance and insulin sensitivity respectively. RESULTS: Not all means of the fasting plasma glucose levels amongst the four groups of women were equal (p < 0.001), with all possible comparisons being significant except for the first and second trimester groups. Among the comparisons of the means of the glucose:insulin ratio in the four groups of women, only the means of the first and second trimester women differed (mean difference = 0.23, honestly significance difference = 0.20). All groups were comparable in the means of plasma insulin, C-peptide levels and the C-peptide:insulin ratio. CONCLUSION: Since fasting plasma insulin, C-peptide and C-peptide:insulin ratio were not significantly altered in all trimesters of pregnancy, these data suggest normal basal insulin secretion and clearance during gestation in these sub-Saharan African women.

Analysis of Variance↗
PubMed2000

The technologies of time measurement: implications at the bedside and the bench.

This essay explores how chronologically linked indices of health and illness, such as variation in body temperature, achieved clinical and scientific significance. It shows why time has been a potent concept through which key associations among the data of medicine are ordered and revealed, and it examines the graphical and case reporting methods of organizing evidence that made such associations possible.

History, 16th Century↗
PubMed1994

Physicians and economics: a commentary.

This article discusses the physician in the United States in relationship to economics. Because economics forms the basis of most of the debate concerning health care in this country, it is important to look at the physician's background, position, and future as they relate to this important area. Eight economic encounters met by the physician are considered: the physician's relationships with knowledge, patients, peers, hospitals, medical technology, malpractice, managed care, and the future. The purpose is to encourage discussion and introspection and to suggest possible future avenues of education and training to address more completely the economic necessities that now are so closely entwined with the profession.

Delivery of Health Care↗