Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Lymphography”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 109 records · Page 6Linked to original sources
PubMedDate not supplied

3-dimensional computed tomography lymphography-guided identification of sentinel lymph nodes in breast cancer patients using subcutaneous injection of nonionic contrast medium: a clinical trial.

OBJECTIVE: Simple and reliable identification methods for sentinel lymph nodes (SLNs) which do not use radioisotope are essential for early breast cancer patients in community hospitals in Japan. The purpose of this paper is to demonstrate the feasibility and efficacy of computed tomography (CT) lymphography for SLN detection. METHODS: The study included 15 cases with T1 or T2 breast cancer. After subcutaneous injection of 1 mL of iopamidol in 1 subareolar area of the affected breast, CT scanning was carried out and 3-dimensional (3D) CT images were created. SLNs predicted from images and CT values were assessed as to whether they were identical to those identified by the dye method. RESULTS: An enhanced lymph vessel draining into SLN was demonstrated in 11 cases (73%) and an enhanced SLN in 10 cases (67%). 3D images clearly revealed the anatomic relationship between lymph vessels, SLN, and the surrounding structures. In addition, SLN could be predicted by the change of CT value in the time-course in another case. In total, SLN in 13 cases (87%) could be predicted. All SLNs suggested from CT lymphography were identified by the dye method. No significant adverse effect was noted in any case. CONCLUSIONS: The present clinical trial indicated that subcutaneous injection of nonionic contrast medium with CT scanning seems to be a promising method for the demonstration of a draining lymph vessel and SLN. The CT value time-course may also provide some important information. Further trials will be needed for the successful establishment of this CT lymphography-guided method for SLN identification.

Adult↗
PubMed2007

Magnetic resonance lymphography.

PURPOSE OF REVIEW: The current methods of noninvasively staging retroperitoneal lymph nodes are suboptimal. Magnetic resonance lymphography is a new technique that might offer an important new tool in this area. Although it is still in development, more and more studies show that it is highly effective in detecting nodal metastases of various tumors. RECENT FINDINGS: Magnetic resonance lymphography yields higher sensitivity than the reference methods for detecting malignant nodes in patients with prostate, bladder, or testicular cancer. SUMMARY: In certain groups of patients with urologic cancer, magnetic resonance lymphography may obviate the need for lymphadenectomy and replace the currently used computed tomography scanning or unenhanced magnetic resonance imaging that are based on insensitive size criteria.

Diagnosis, Differential↗
PubMed1975

Role of lymphography in carcinoma of the prostate.

The results of bilateral pedal lymphography in 83 patients with adenocarcinoma of the prostate gland are presented. The patients were divided into two groups: 45 new cases and 38 late or old cases presenting several years after the onset of the disease. Altogether 25 of the new patients and 29 of the late patients had lymphographic evidence of lymph node metastases. The lymphogram results in relation to local tumour size, histological grade, the presence of skeletal metastases, and acid phosphatase levels are discussed. Of the new patients with T1 and T2 tumors--that is, those still localized within the prostatic capsule--41% had positive lymphograms. The inaccuracy of acid phosphatase estimations in detecting early extraprostatic spread is shown and compared with the greater accuracy of lymphography. Lymphography should be used as an initial investigation in all cases where aggressive therapy is being considered, and the importance of regular follow-up radiographs is emphasized.

Acid Phosphatase↗
PubMed1975

Lymphography in carcinoma of the uterine cervix.

Lymphography was carried out in a series of 158 patients with carcinoma of the uterine cervix. The diagnostic accuracy rate of 85 per cent compares favourably with the results of a similar investigation made ten years ago. Positive lymphography does not alter the survival rate in clinical stages I and II, probably due to the more accurate and selective therapeutic approach induced by lymphography. In stage III the 2-year survival rate of patients with negative findings is 58 per cent compared to only 17 per cent in case of positive lymphographic findings.

Adult↗
PubMed1982

Computed tomography, ultrasound and lymphography in the diagnosis of malignant lymphoma.

Lymphographic findings were compared with the results at histopathology in 42 laparotomized patients with malignant lymphoma. Of 12 patients with lymphographically suggested lesions in normal-sized lymph nodes, only one had pathologic changes at histologic examination. Computed tomography gave a better idea of the extent of the disease than lymphography. Moreover, CT had an equal diagnostic accuracy as lymphography for demonstrating enlarged para-aortic lymph nodes. CT should therefore be able to replace lymphography in examination of malignant lymphoma. Ultrasound had the same diagnostic accuracy as CT regarding the upper and middle abdomen but not in the lower abdomen. Ultrasound is of special value in thin patients and when guided needle biopsy is required.

Body Weight↗
PubMed2000

Magnetic resonance lymphography of profundus lymph nodes with liposomal gadolinium-diethylenetriamine pentaacetic acid.

Lymphography, especially imaging of profundus lymph nodes, is a useful tool for diagnosis of cancer metastases in lymph nodes. However, positive enhancement agents for magnetic resonance lymphography (MRL) have not been available, since the positive imaging agents so far introduced are low-molecular-weight materials that are not trapped in lymph nodes. For the purpose of improved positive enhanced MRL, we employed liposomes as carriers of a positive enhancer, gadolinium-diethylenetriamine pentaacetic acid (Gd-DTPA). Magnetic resonance (MR) imaging was performed after subcutaneous injection of Gd-liposomes into the hind feet of rabbits which had reactive enlarged retroperitoneal lymph nodes. As a result, not only popliteal but also profundus retroperitoneal lymph nodes were positively enhanced by Gd-liposomes, especially after 20 min massage of the injected sites. Gd-Liposomes containing dipalmitoylphosphatidylglycerol were more effective than Gd-liposomes containing palmityl-D-glucuronide, a type of long-circulating liposomes, suggesting that liposomal accumulation in lymph node is, at least partly, mediated by the trapping of liposomes by macrophages. These data show that liposomes modified with Gd-DTPA are effective for positive enhancement of both regional and profundus lymph nodes in MR lymphography.

Animals↗
PubMed1985

Abdominal lymphoscintigraphy: an effective substitute for lymphography?

Abdominal lymphoscintigraphy is a quick, easy, cheap and relatively non-invasive technique. In our study it appeared to be as accurate as lymphography, giving a positive correlation in 25 out of 32 patients (78%). In 11% of cases the lymphoscintigram detected an abnormality of lymph node function before macroscopic morphological change was seen in the lymphogram, indicating that in some instances lymphoscintigraphy is more sensitive than lymphography. The reason for this is unknown, although possible mechanisms are discussed and these are the subject of current further study. We believe this to be the first report of lymphoscintigraphy being more sensitive than lymphography for detecting lymph node disease.

Abdomen↗
PubMed1990

Staging of Hodgkin disease in children: comparison of CT and lymphography with laparotomy.

Proper therapy for Hodgkin disease requires accurate staging of the disease. We compared the value of CT and lymphography with that of laparotomy for staging newly diagnosed Hodgkin disease in 46 children. The laparotomy revealed disease in one or more subdiaphragmatic sites in 46%. Correlation of the imaging studies with the laparotomy findings showed that lymphography has a greater sensitivity (80%) than does CT (40%) in detecting retroperitoneal lymph nodes. The sensitivity of CT in detecting splenic involvement was only 19%, presumably because of the small size of tumor deposits in involved spleens. Staging laparotomy altered the clinical stage in 37% of children, which resulted in a significant change of therapy in those patients. Although lymphography and, to a lesser degree, CT are useful for staging of Hodgkin disease, laparotomy continues to be the most important tool in choosing appropriate therapy for children with Hodgkin disease.

Adolescent↗
PubMed1992

Current use of lymphography for staging lymphomas and genital tumors.

The current literature and the experience at The University of Texas M.D. Anderson Cancer Center were reviewed to determine the current status of the use of lymphography for staging of malignant disease. Lymphography continues to be used for staging and surveillance of the lymphomas and, to some extent, for staging of carcinoma of the cervix. Testicular tumors are now primarily staged and followed by CT and serum markers. Currently, other abdominal and pelvic tumors are not commonly evaluated with lymphography.

Female↗
PubMedDate not supplied

Detection of neoplastic lymph nodes in Hodgkin's disease and non-Hodgkin lymphoma. Comparison between tomography and lymphography.

During a period of 17 months, 98 consecutive patients with malignant lymphoma were examined for initial staging before therapy. Both CT and lymphography were performed in 58 patients (19 patients with Hodgkin's disease (HD) and 39 patients with non-Hodgkin lymphoma (NHL], and these were included in the investigation. The results were discrepant in 26 cases where lymph node lesions were detected by only one of the two methods. In 10 patients, 5 with HD and 5 with NHL, the positive finding by one of the methods was taken as determinant of the stage. The conclusion drawn was that CT cannot completely replace lymphography without losing important information. Owing to limited resources for lymphography and CT a reduced staging programme is proposed. Judging by the present results, this reduced programme would probably mean only a minimal loss of information.

Biopsy↗
PubMed1991

[Direct lymphography with special reference to peripheral lymphedema. Historical retrospect--technique--indications--alternative procedures--image documentation].

Indication for direct lymphography during the past forty years shows a downward tendency, mainly because of new alternative modern imaging methods. Nevertheless, in agreement with the actual literature it can be shown by own investigations with 8000 patients from 1964 to 1989 that one cannot give up lymphography totally. On principle lymphography is still carried out in case of testicular tumors, malignant lymphomas, unclear fever, lymphatic vessel injury and facultative in peripheric lymph edemas.

Humans↗
PubMed1990

[Indirect lymphography for diagnosis of limb lymphedema].

Twenty patients with various forms of lymphedema were studied by indirect lymphography. Isovist (Schering AG, Berlin) used for intradermal infusion is a new non-ionic, water-soluble, dimeric contrast media. It has following advantages: ideal iso-osmolarity, lowest physical-chemicotoxicity, and excellent tissue tolerance. Simultaneous indirect lymphography was recommended. Characteristic patterns of lymphatics were demonstrated. The newly developed Isovist allows visualization of initial lymphatics by intradermal infusion. However they are not displayed with direct lymphography unless in the presence of valvular insufficiency. It can be performed within 30 minutes. No chemical injury to lymphatics would happen so that this procedure could performed repeatedly.

Adolescent↗
PubMed1990

[Ultrasonic examination and lymphography in the diagnosis of metastases of rectal cancer].

The diagnostic effectiveness of ultrasound and lymphographic investigations was assessed in 89 rectal cancer patients. Lymphography was shown to be a more informative method as it permitted the detection of metastases in 6 patients in whom USI results were negative, metastatic involvement in 2 patients, specifying the type of pathological changes of the enlarged lymph nodes in 14 patients. In a normal lymphographic picture metastatic involvement was detected in 37 cases using echography. More extended metastatic spreading was found on USI (as compared to lymphography) in one patient. The combined use of echography and lymphography improved the diagnosis of rectal cancer lymphogenous metastases.

Adult↗
PubMed1990

[Diagnostic value and criteria for evaluating indirect lymphography in lymphedema].

To evaluate the deciding diagnostic criteria of indirect lymphography in lymphoedema of the leg, 91 investigations were reviewed. 72 examinations were from lymphoedematous legs as judged by clinical appearance and isotopic lymphography and 19 from healthy legs. After subepidermal infusion of adequate water soluble contrast media (e.g. Jotrolan) in healthy legs, 17 from 19 cases showed normal ellipsoid dye-deposits with normally structured lymph-collectors. In two cases pathological lymph-collectors were shown (specificity 89%). In the 72 legs with lymphoedema the most prominent pathological features were altered lymph-collectors and/or dermal backflow. Only two cases revealed a normal pattern (Sensitivity 97%). Indirect lymphography therefore may be recommended as a sensitive but less specific diagnostic tool for proving lymphoedema in a suspected clinical situation.

Adolescent↗
PubMed1990

[The importance of lymphography in melanoma].

It is a pity that, in view of its important prognostic value and for technical reasons, or because of problems of interpretation, lymphography should no longer be part of a routine work-up for diagnosing melanoma. Indeed, bipedal lymphography can accurately reveal the extent of node invasion in case of palpable adenopathy. It provides for the monitoring of the retroperitoneal lymph nodes after inguinal curettage has been accomplished. This method may reveal metastases at the subclinical stage. Axillary lymphography is especially valuable in case of palpable adenopathy. It has prognostic value in case of positive isotopic-clinical node involvement. Above all, however, it enables discarding the diagnosis of any secondary invasion, and preventing otherwise systematic axillary node curettage in 41% of cases. Lastly, if findings are normal, it affords a means for long-term follow-up.

Axilla↗
PubMed1989

[X-ray contrast lymphography in the differential diagnosis of ovarian tumors and lesions of the lymph nodes].

The authors analyzed the results of lymphography, performed in 58 patients examined for small pelvic tumors, interpreted first as ovarian tumors. The evaluation of the lymphography results made it possible to rule out ovarian neoplasms in 17 of 58 patients and to reveal in them pelvic lymph node lesions classified as fatty degeneration of the lymph nodes (9 cases), lymphosarcoma (5 cases), sarcoidosis (2 cases), and lymphoendothelioma (one case). A high informative value of lymphography in differential diagnosis between ovarian tumors and lesions of the pelvic lymph nodes was established.

Adult↗
PubMed1988

Oil contrast lymphography and respiratory function.

We reviewed our experience with direct oil contrast lymphography for pulmonary complications in more than 1500 lymphangiograms done since 1969. The vast majority of patients showed little subjective or objective (chest x-ray, pulmonary function test, and gas exchange) evidence of oil embolization even in those with mild to moderate cardiopulmonary disease. In 1% there was evidence on chest x-ray 24 hours after lymphography of tiny patchy infiltrates consistent with oil emboli. Although the indications for oil contrast lymphography have been sharply restricted with availability of newer imaging methods, it is nonetheless a safe and well-tolerated procedure even in patients with mild to moderate pulmonary dysfunction.

Adult↗