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At least 109 records · Page 6Linked to original sources
PubMed2005

Public assistance orthodontic treatment needs: a report from the state of Indiana.

OBJECTIVE: To determine how many of the orthodontic cases covered by Indiana Medicaid between 1999-2001 would be classified pretreatment as having a malocclusion severe enough to warrant treatment. METHODS: Six examiners were trained and then paired together to examine 249 patient orthodontic case records, consisting either of pre-treatment photographs only, pre-treatment models only, or both pre-treatment models and photos. The examiners applied the Index of Orthodontic Treatment Needs (IOTN) to assign each case a Grade of One to Five, with Grade One representing Ideal Occlusion and Grade Five being Extreme Malocclusion. When two examiners within a pair could not agree, a third examiner reviewed the case record to determine agreement. RESULTS: Of the 249 patient cases examined, 9 were not gradable. In the cases where only pretreatment models were available (n=157), 10% received a Grade of One or Two (Ideal Occlusion or Mild Malocclusion, respectively). Among the cases in which both pretreatment models and photos were available (n=46), 44% of the photos were graded One or Two, while only 2% of the models were graded as One or Two. In the cases where only pretreatment photographs were available (n=37), 27% of cases were Grade One or Two. CONCLUSION: While several of the cases (11%) submitted during the time period of 1999 to 2001 to the Indiana State Medicaid Division for reimbursement were rated as having Ideal Occlusions or Mild Malocclusions, the vast majority (89 %) were scored as having either Moderate, Severe, or Extreme Malocclusion.

Dental Health Surveys↗
PubMed1972

Vesicular stomatitis virus (Indiana serotype): transovarial transmission by phlebotomine sandlies.

Transovarial transmission of vesicular stomatitis virus (Indiana serotype) by experimentally infected Lutzomyia trapidoi and Lutzomyia ylephiletrix to their progeny was demonstrated. Virus was recovered from all developmental stages; mean virus titers from egg to first generation adult showed a four-log increase, indicating that virus multiplication occurred during development of the sandflies. Virus titers in first generation adult females were comparable to those found in their parents. These infected female sandflies transmitted vesicular stomatitus virus Indiana by bite to susceptible animals and transmitted the virus transovarially to their offspring (second generation). Results demonstrate a possible mechanism for transmission and maintenance of this virus in nature without a vertebrate (heat) host reservoir.

Animals↗
PubMed2005

Biological differences between vesicular stomatitis virus Indiana and New Jersey serotype glycoproteins: identification of amino acid residues modulating pH-dependent infectivity.

We previously generated recombinant vesicular stomatitis viruses (VSV) based on the Indiana serotype genome which contained either the homologous glycoprotein gene from the Indiana serotype (VSIV-GI) or the heterologous glycoprotein gene from the New Jersey serotype (VSIV-GNJ). The virus expressing the GNJ gene was more pathogenic than the parental VSIV-GI virus in swine, a natural host (26). For the present study, we investigated the biological differences between the GI and GNJ proteins that may be related to the differences in pathogenesis between VSIV-GI and VSIV-GNJ. We show that the capacities of viruses with either the GNJ or GI glycoprotein to infect cultured cells differ depending on the pH. VSIV-GNJ could infect cells at acidic pHs, while the infectivity of VSIV-GI was severely reduced. VSIV-GNJ infection was also more sensitive to inhibition by ammonium chloride, indicating that the GNJ protein had a lower pH threshold for membrane fusion. We applied selective pressure to VSIV-GI by growing it at successively lower pH values and isolated variant viruses in which we identified amino acid changes that conferred low-pH-resistant infectivity. Repeated passage in cell culture at pH 6.8 resulted in the selection of a VSIV-GI variant (VSIV-6.8) that was similar to VSIV-GNJ regarding its pH- and ammonium chloride-dependent infectivity. Sequence analysis of VSIV-6.8 revealed that it had a single amino acid substitution in the amino-terminal region of the glycoprotein (F18L). This alteration was shown to be responsible for the observed phenotype by site-directed mutagenesis of a VSIV-GI full-length cDNA and analysis of the recovered engineered virus. A further adaptation of VSIV-6.8 to pHs 6.6 and 6.4 resulted in additional amino acid substitutions in areas of the glycoprotein that were not previously implicated in attachment or fusion.

Amino Acid Substitution↗
PubMed1984

Effect of the air hammer on the hands of stonecutters. The limestone quarries of Bedford, Indiana, revisited.

In the limestone quarries of Indiana, USA, pneumatic percussive hammers replaced the mallet and hammer around 1900. By 1917 the air hammer was being used exclusively for periods of eight to ten hours a shift. In 1918 Alice Hamilton investigated an unusual "disease" in these stonecutters of Bedford, Indiana, who complained of "attacks of numbness and blanching of the fingers coming on suddenly under the influence of cold and then disappearing." The prevalence of vibration induced white finger (VWF) found in this population of 38 stonecutters was 89%, with decreased light touch, pain, and temperature appreciation in advanced cases. In 1978 a VWF research team revisited these limestone quarries. During the 60 year interval the stonecutting industry had contracted from 4000 workers in 40 quarries in 1918 to 3-400 in 10 quarries in 1978, with only 50 employees remaining in the Bedford area. In a population of 30 stonecutters the prevalence of VWF in 1978 was 80%, with similar sensory loss in light touch, pain, and temperature appreciation. Between 1918 and 1978 no change had taken place in the design of the air hammers used for stonecutting. Vibration levels of 4859 metres/s2 on the chisel, and 2010 metres/s2 on the barrel were measured over a frequency range 6.3 to 1000 Hz. The fundamental frequency was 75 Hz. These measured vibration levels are outside the ISO/DIS/5349 (1979) recommended limits for human exposure to vibration transmitted to the hand. The VWF data presented in this paper, and those originally reported by Hamilton in 1918, call for an immediate redesign of stonecutting pneumatic hammers in order to remove one cause of Raynaud's phenomenon of occupational origin.

Adult↗
PubMed2000

Project: HIV prevention for incarcerated youth in Indiana.

Both Indiana and national statistics suggest that HIV-AIDS cases continue to rise in the adolescent population. Because of environmental factors, incarcerated adolescents may be at a greater risk of exposure to HIV-AIDS. Educational programs, such as the one funded for this project, may be an important step in impacting the current pandemic nature of HIV-AIDS. An educational project consisting of 4 peer-based, interactive sessions was developed for incarcerated adolescents in a north central Indiana juvenile center. The project sessions were developed from the National Network of Runaway and Youth Services (1994). Project objectives were based on the AIDS Risk Reduction Model (ARRM) and were measured by a 40-item tool developed from the ARRM. Project objectives were as follows: Detainees would (a) participate in 4 educational sessions related to high-risk sexual behavior, (b) recognize and label their own sexual behaviors that put them at risk for contracting AIDS, and (c) make a commitment to reduce high-risk sexual behaviors. During the first year of state funding, 91 educational sessions were conducted, reaching a total of 196 detainees. Following comparisons of the preproject and postproject questionnaires, detainees demonstrated an increase in their ability to appropriately recognize and label risky behaviors, but they evidenced no significant commitment to change their behaviors.

Adolescent↗
PubMed2006

Mortality among workers exposed to polychlorinated biphenyls (PCBs) in an electrical capacitor manufacturing plant in Indiana: an update.

An Indiana capacitor-manufacturing cohort (n=3,569) was exposed to polychlorinated biphenyls (PCBs) from 1957 to 1977. The original study of mortality through 1984 found excess melanoma and brain cancer; other studies of PCB-exposed individuals have found excess non-Hodgkin lymphoma and rectal, liver, biliary tract, and gallbladder cancer. Mortality was updated through 1998. Analyses have included standardized mortality ratios (SMRs) and 95% confidence intervals (CIs) using rates for Indiana and the United States, standardized rate ratios (SRRs), and Poisson regression rate ratios (RRs). Estimated cumulative exposure calculations used a new job-exposure matrix. Mortality overall was reduced (547 deaths; SMR, 0.81; 95% CI, 0.7-0.9). Non-Hodgkin lymphoma mortality was elevated (9 deaths; SMR, 1.23; 95% CI, 0.6-2.3). Melanoma remained in excess (9 deaths; SMR, 2.43; 95% CI, 1.1-4.6), especially in the lowest tertile of estimated cumulative exposure (5 deaths; SMR, 3.72; 95% CI, 1.2-8.7). Seven of the 12 brain cancer deaths (SMR, 1.91; 95% CI, 1.0-3.3) occurred after the original study. Brain cancer mortality increased with exposure (in the highest tertile, 5 deaths; SMR, 2.71; 95% CI, 0.9-6.3); the SRR dose-response trend was significant (p=0.016). Among those working >or= 90 days, both melanoma (8 deaths; SMR, 2.66; 95% CI, 1.1-5.2) and brain cancer (11 deaths; SMR, 2.12; 95% CI, 1.1-3.8) were elevated, especially for women: melanoma, 3 deaths (SMR, 5.99; 95% CI, 1.2-17.5); brain cancer, 3 deaths (SMR, 2.87; 95% CI, 0.6-8.4). These findings of excess melanoma and brain cancer mortality confirm results of the original study. Melanoma mortality was not associated with estimated cumulative exposure. Brain cancer mortality did not demonstrate a clear dose-response relationship with estimated cumulative exposure.

Adult↗
PubMedDate not supplied

The Indiana network for patient care: a working local health information infrastructure. An example of a working infrastructure collaboration that links data from five health systems and hundreds of millions of entries.

The Indiana Network for Patient Care (INPC) is a local health information infrastructure (LHII) that includes information from the five major hospital systems (fifteen separate hospitals), the county and state public health departments, and Indiana Medicaid and RxHub and that carries 660 million separate results. It provides cross-institutional access to physicians in emergency rooms and hospitals based on patient-physician proximity or on hospital credentialing. The network includes and delivers laboratory, radiology, dictation, and other documents to a majority of Indianapolis office practices. The INPC began operation seven years ago and is one of the first and best examples of an LHII.

Cooperative Behavior↗
PubMed2002

Making better babies: public health and race betterment in Indiana, 1920-1935.

In 1920, Indiana's Division of Infant and Child Hygiene inaugurated its first Better Babies Contest at the state fair. For the next 12 years, these contests were the centerpiece of a dynamic infant and maternal welfare program that took shape in Indiana during the decade of the federal Sheppard-Towner act. More than just a lively spectacle for fairgoers, these contests brought public health, "race betterment," and animal breeding together in a unique manner. This article describes one of the most popular expressions of public health and race betterment in rural America. It also raises questions about the intersections between hereditarian and medical conceptions of human improvement during the early 20th century, especially with respect to child breeding and rearing.

Child Welfare↗
PubMed1976

Variant infectious bronchitis virus isolated from Indiana chickens.

Infectious bronchitis virus (IBV) associated with a catarrhal tracheitis, sudden decline in egg production, and reduced shell quality was isolated from an Indiana White Leghorn breeder flock. It was found to be serologically different from Massachusetts, Connecticut, Iowa 97, Iowa 609, Florida, Arkansas 99, JMK, Holte, Gray and SE 17 IBV serotypes. Two different Massachusetts vaccine strains protected chickens from respiratory signs but not against virus infection using the isolant for challenge in laboratory trials. The isolant was passed through a 0.22 mu. filter. It was heat (56 C), acid pH (3.0), ether and chloroform labile. In embryos it produced deaths or lesions of infectious bronchitis in one to five days after inoculation. It is suggested that this IBV isolant be designated Indiana-type.

Animals↗
PubMedDate not supplied

The impact of participation in health promotion on medical costs: a reconsideration of the Blue Cross and Blue Shield of Indiana study.

PURPOSE: The purpose of this study was to investigate whether participation in a comprehensive worksite health promotion program was associated with reduced employee health care costs. DESIGN: Four independent study groups, two treatment and two comparison, were identified based on type and date of first participation in the intervention. Two years of pre-program health cost data and five years of post-program data were collected for each subject. The Jonckheere-Terpstra statistical test was used to analyze the data. SETTING: The health promotion program was offered at Blue Cross and Blue Shield of Indiana corporate headquarters. The study period began on January 1, 1976, and continued through December 31, 1982. SUBJECTS: Seven hundred and forty-three men and women employed continuously by Blue Cross and Blue Shield of Indiana throughout a seven-year period were studied. INTERVENTION: The health promotion program consisted of four progressive phases which involved 1) health risk reduction mass education, 2) completion of a health risk appraisal and risk reduction counseling, 3) health promotion classes such as smoking cessation and nutrition education, and 4) follow-up and maintenance. MEASURES: The principal dependent variable was pre-program to post-program changes in health costs as measured by employee health care expense claims paid for by the company's health insurance plan. RESULTS: This study found that program participation was not associated with reduced health care costs. CONCLUSIONS: It would be prudent to remain guarded about the health cost savings effects of worksite health promotion programs.

Adult↗
PubMedDate not supplied

Canine distemper infection in pet dogs: I. Surveillance in Indiana during a suspected outbreak.

A mail survey of 613 private veterinary practices in Indiana was conducted to determine the prevalence of canine distemper infection in Indiana during 1991 and 1992 and to compare the prevalence in three geographic regions. Of the practices that were contacted, 223 (37%) responded. Canine distemper had been diagnosed by 150 (67%) of the 223 practices. The period prevalence increased significantly from 11.1 to 16.9 cases per 10,000 dog visits. Surveillance of private veterinary practices may be useful to confirm suspected outbreaks of diseases in companion animals.

Animals↗
PubMedDate not supplied

Inhalant use among indiana school children, 1991-2004.

OBJECTIVE: To examine the prevalence and trend of inhalant use among Indiana public school students. METHODS: The Alcohol, Tobacco, and Other Drug Use among Indiana Children and Adolescents surveys conducted annually between 1991 and 2004 were reanalyzed using 2-way moving average, Poisson regression, and ANOVA tests. RESULTS: The prevalence had increased during 1991- 1997, decreased during 1997- 2002, and increased again since 2003. Poisson model estimated an average annual decrease rate of 5.6%. The intensity of inhalant use had also decreased. More males and Hispanics use inhalants. CONCLUSION: Inhalant use needs to be addressed in drug prevention programs.

Adolescent↗
PubMed1979

A major focus of Legionnaires' disease in Bloomington, Indiana.

Thirty-nine cases of Legionnaires' disease in a 16-month period were identified in visitors to and residents of Bloomington, Indiana. Thirty-five patients had spent at least one night at the Indiana Memorial Union in the 2 weeks before becoming ill. Five of 32 sporadic cases nationwide between 1 January and 31 March 1978 were retrospectively shown to be in persons who had recently visited the Union. The risk of acquiring Legionnaires' disease as a Union visitor was at least 17 times greater than that for Bloomington residents 20 years or older. Employees who had worked at the Union 5 years or longer were more likely to be seropositive than workers in other Bloomington hotels. Legionnaires' disease bacterium was isolated from five environmental sites in Bloomington. A cooling tower may have been involved in disease spread, but it was not the only source. Hypochlorite solution was added to cooling tower water as a precautionary measure; however, one case was confirmed in a man with Union exposure 9 days after hypochlorite treatment had begun.

Adult↗
PubMed1997

A small-scale survey of hantavirus in mammals from Indiana.

In order to determine if hantaviruses were present in mice and other small mammals in Indiana (USA), small mammals were trapped in Brown, LaPorte, Tippecanoe and Whitley counties. Sixty-seven small mammals were trapped during August and September 1994. Sixty-three Peromyscus leucopus, one Microtus pennsylvanicus, one Zapus hudsonius and two Blarina brevicauda were captured and tested for hantaviruses. Six P. leucopus were found to have antibody to Sin Nombre virus (SN) by IgG ELISA, and a 139 bp fragment of SN-like hantavirus was amplified from five of them. All six of the positive P. leucopus were from LaPorte County. No other small mammals had evidence of infection with SN virus. This study presents the first report of Sin Nombre-like hantavirus in P. leucopus from Indiana.

Animals↗
PubMed1983

Operational characteristics of hospital pharmacies in Indiana--1976 vs. 1981.

The operating characteristics and services provided by hospital pharmacies in Indiana were determined. Survey questionnaires were mailed to the pharmacy director for each of the 120 licensed hospitals in Indiana; 62 responded. Pharmacy departments were open an average of 106.3 hours weekly, 51 pharmacies maintained patient profiles, and 29 pharmacies used unit-dose for all beds. Involvement in preparing I.V. solutions was reported by 67.7% of the pharmacies. The mean number of total pharmacy staff (FTEs) reported was 17.1. The ratio of staff FTEs per patient day was larger for pharmacies using a unit-dose distribution system. The most commonly provided clinical services were drug consultation with nursing, drug utilization review, and inservice education. Ratios of average dollar drug inventory and operating expenses per patient day indicated that larger hospitals were more effective with inventory control, but had higher expenses per patient day.

Analysis of Variance↗
PubMed1999

Dental assistants of Indiana: comments from the front lines.

During the summer of 1996, a random sample survey of 1500 Indiana dental assistants licensed in radiology by the Indiana State Board of Health was conducted. Surveys were mailed to participants, and follow-up postcard reminders were sent out a few weeks later. There were 569 surveys returned, representing a 38 percent return rate. Numerical data were coded and entered in an SPSS program, and written comments were analyzed independently by the co-authors. Major demographic data and many categories of open-ended comments are summarized and analyzed in this paper. Results from this survey underscore the necessity for wages being improved in the dental assisting field. Comments underscore the fact that many dental assistants are not satisfied with their jobs and therefore may not be committed to either their careers or their employers. Office climate and relationships with the dentist are also described as being very important.

Adolescent↗
PubMedDate not supplied

The prescription of transdermal nicotine patches for tobacco-using dental patients: current status in Indiana.

As Indiana dentists become involved in office-based smoking cessation efforts, they can prescribe the recently-developed Federal Drug Administration (FDA)-approved nicotine transdermal patch delivery systems for their smoking patients who wish to overcome nicotine addiction. This article reviews the evolutionary and scientific development of transdermal nicotine patch systems within an oral health setting. It discusses dental office-based cessation programs which have been designed by faculty members at the Indiana University School of Dentistry and by dentists who work with the National Cancer Institute. Finally, it presents the rationale for patch usage and specific techniques which are utilized in prescribing and monitoring this medication.

Administration, Cutaneous↗
PubMedDate not supplied

A manpower study of orthodontic specialists for the State of Indiana: a preliminary report.

To develop current manpower data and project the future need for orthodontic specialists, a survey questionnaire was mailed to Indiana orthodontists (90 percent response). In addition, a telephone survey of orthodontic receptionists was conducted during the same time period (95 percent response). In general, orthodontists perceived a lower state of business than did their staffs. About 77 orthodontists are expected to retire by the year 2010. Based on maintaining the adjusted potential patient-to-orthodontist ratio (increasing adult and declining children in the population), it was projected that only about 66 (86 percent) of the retirees require replacement. To maintain manpower at eight percent fewer orthodontists than are currently in practice, three to four new orthodontists per year will be needed in Indiana over the next two decades.

Chi-Square Distribution↗