SYNTHETIC MECHANISMS IN THE AXON. I. LOCAL AXONAL SYNTHESIS OF ACETYLCHOLINESTERASE.
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Equations based on the assumption of a reversible first step in the reaction between organophosphate inhibitors and esterases are proposed for the bimolecular rate constant which now includes an affinity constant and a phosphorylation constant. The treatment applies when the inhibition reaction follows first-order kinetics.
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