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At least 109 records · Page 6Linked to original sources
PubMed2005

The Finger iridectomy technique: small incision biopsy of anterior segment tumours.

AIMS: To develop a minimally invasive, maximally effective method to biopsy anterior segment tumours. METHODS: A 25 gauge aspiration cutter (vitrector) was used to biopsy anterior segment tumours. The probe was introduced under sodium hyaluronate 1% and through a 1 mm incision. Aspiration (600 mm Hg) cutting (300 cpm) was performed to obtain specimens for cytology and histopathology. RESULTS: Diagnostic material was obtained in nine of 10 (90%) cases. Diagnoses included iris naevus, iris stroma, malignant melanoma, melanocytoma, epithelial inclusion cyst, and sarcoid granuloma. All corneal wounds were self sealing. One patient developed a transient postoperative increase in intraocular pressure. Within the follow up of this study, no patients suffered intraocular haemorrhage, infection, cataract or vision loss. CONCLUSION: The Finger iridectomy technique was a minimally invasive and very effective biopsy technique. Aspiration cutting yielded relatively large pieces of tissue (and cells) used for cytopathological and histopathological evaluation. Small incision surgery allowed for rapid rehabilitation and no significant complications.

Adult↗
PubMed1975

Peripheral iridectomy with scleral cautery for glaucoma.

Peripheral iridectomy with cautery (Scheie operation) was carried out on 113 eyes with glaucoma. The results were so favorable and the complications so few that we believe this operation still has an important place in the surgical management of the glaucomas and is noteworthy in the light of the trend to more precise surgery of the canal of Schlemm and the trabeculae.

Anesthesia, Local↗
PubMed1979

Provocation and mechanism of angle-closure glaucoma after iridectomy.

Dark room tests and prone-position tests in a lighted room and in a dark room were carried out on 64 eyes in 32 normal patients and 37 eyes of 30 patients that had undergone complicated iridectomy. Among the iridectomized eyes, the dark room tests and the prone-position test in lighted room caused elevation of intraocular pressure of more than 8 mm Hg in only 2.7% and 16.2%, respectively. Nearly 60% of the eyes showed positive results when the prone-position test was performed in a dark room. Our findings may provide experimental support for the theory of direct lens block as an angle-closure mechanism.

Darkness↗
PubMed1982

Iridectomy in the surgical management of eight-ball hyphema.

The complete absorption of blood in patients with eight-ball hyphema and medically uncontrollable intraocular pressure occurred after iridectomy. No intra-operative complications were noted. Six of the seven patients maintained normal IOPs without medical therapy for at least six months postoperatively. Pupillary block by the clotted blood and the tamponade effect exerted by the total hyphema on the outflow pathway are possible mechanisms of the secondary glaucoma.

Adolescent↗
PubMed1985

Laser iridotomy vs surgical iridectomy. Have the indications changed?

The number of laser iridotomies in 1982 was more than four times the annual rate of surgical iridectomies performed before the laser was in common use at the Bascom Palmer Eye Institute, Miami. No single reason accounts for the increase. Only a minority of the increase is due to a 32% increase in our outpatient volume, a backlog of individuals with borderline indications who had not undergone surgery, or the number of iridotomies performed prophylactically for asymptomatic narrow angles. The proportion of eyes treated for each of several classic indications (acute attacks, chronic angle closure with pressure elevation or synechiae, aphakic pupillary block, etc) remained the same. However, eyes with acute attacks and their fellow eyes had iridotomy more promptly and more often with the availability of laser. In addition, the laser was applied earlier in the course of chronic angle closure. We believe that the increased use of an easy, low-risk procedure represents an improvement in the quality of care.

Adult↗
PubMed1997

Isolation and culture of iris pigment epithelium from iridectomy specimens of eyes with and without exfoliation syndrome.

OBJECTIVE: To culture iris pigment epithelium (IPE) from surgical iridectomy specimens of eyes with and without exfoliation syndrome. METHODS: The IPE was treated to obtain a single cell suspension. Cells were cultured in Ham F12 nutrient mixture, which was supplemented with 30% fetal bovine serum, 50-micrograms/mL [corrected] gentamicin, and 2-mmol/L glutamine. After confluence, the cells were detached using a 0.125% trypsin-0.01% edetic acid solution, resuspended, diluted, and subcultured. The IPE from primary cultures and subcultures was studied by transmission electron microscopy. Immunocytochemical staining was performed. RESULTS: In the primary cultures of IPE from patients with exfoliation syndrome, curved, cross-banded, fine fibrils (diameter, 10-15 nm; periodicity, 10-14 nm) were found on the cell surface. Thicker fibrils (diameter, 24-48 nm; periodicity, 24-36 nm) were found external to the fine fibrils. Subcultures contained mainly fine fibrils. The IPE cells stained positively with anticytokeratin, S100 protein, and vimentin antibodies. CONCLUSION: Iris pigment epithelium can be successfully cultured from eyes with exfoliation syndrome. Studying the production of exfoliation material in vitro should provide information about the pathogenesis of exfoliation syndrome and about the nature of the exfoliation material. The cultivation of normal IPE from surgical specimens provides a source for the study of the growth regulation and pharmacophysiology of IPE in vitro.

Adolescent↗
PubMed1976

Experimental iridectomy with bipolar microcautery.

Peripheral iridectomy was performed in pigmented rabbits after the application of bipolar microcautery to the iris surface. At low doses of cautery, no increase in postoperative inflammation or complications was noted clinically or pathologically in control eyes. High doses of cautery resulted in an increased incidence of postoperative inflammation, corneal opacity, hyphema, iris prolapse, lens changes, and poor wound healing.

Animals↗
PubMed1980

Central anterior chamber depth after laser iridectomy.

We found the true anterior chamber depth to be unaffected by successful laser iridectomy in ten eyes treated by this modality for chronic angle-closure glaucoma. The apparent general deepening seemed to be the result of peripheral chamber deepening combined with the common use of strong cycloplegic agents, reversing the shallowing effect of preoperative miotic medications.

Anterior Chamber↗
PubMed1989

Thermoelastic analysis of laser iridectomies.

We have attempted to derive the stress-strain-temperature relationships of the iris stroma subject to a restrictive thermal burn from a laser. The corresponding displacement equation embodies the mechanical impulses due to this thermal insult. This thermoelastic analysis of laser iridectomy attempts to describe the mechanism involved in the surgical procedure. It is clear from this study that the flexural behaviour of the iris is principally due to thermal insult and not due to vapour bubbles or redistribution of the aqueous.

Glaucoma, Open-Angle↗
PubMed1986

Total iridectomy does not alter outflow facility responses to cyclic AMP in cynomolgus monkeys.

Total outflow facility was measured by two-level constant pressure anterior chamber perfusion in surgically untouched and totally iridectomized cynomolgus monkey eyes receiving bolus intracameral infusions of cyclic AMP, dibutyryl cyclic AMP, or 5'AMP. Cyclic AMP doses of 50 and 100 micrograms (corresponding to initial intracameral concentrations of 1.5- and 3 mM) increased facility by approximately 20 and 40% respectively in both surgically untouched and aniridic eyes. Higher doses produced no greater effect, and lower doses were ineffective. Dibutyryl cyclic AMP and 5'AMP were ineffective in doses up to 100 micrograms (2- and 3 mM respectively). These findings indicate that the iris plays no mechanical role in mediating the facility response to cyclic AMP, and that the iridectomy procedure per se does not compromise the ability of the outflow pathways to respond to cyclic AMP. Since untouched and aniridic eyes exhibit similar facility responses to epinephrine and norepinephrine, the present findings also suggest that the iris is not the source of cyclic AMP mediating facility responses to catecholamines.

Adenosine Monophosphate↗
PubMed1996

Tissue plasminogen activator for preserving inferior peripheral iridectomy patency in eyes with silicone oil.

PURPOSE: An inferior peripheral iridectomy (IPI) was used to prevent forward migration of silicone oil in vitrectomized eyes; however, in approximately one third of eyes, the IPI closed spontaneously. Occlusion of the IPI by fibrin is believed to be an early event in permanent IPI closure by scar tissue. The authors determined whether intraocular tissue plasminogen activator (tPA) would restore and maintain IPI patency in eyes that had early occlusion of the IPI by fibrin. METHODS: Between November 1993 and January 1995, 12 patients who underwent vitrectomy with silicone tamponade and IPI for complicated retinal detachment received an anterior chamber injection of tPA (6.25 or 12.5 microgram) for occlusion of the IPI by fibrin. RESULTS: All 12 patients had lysis of fibrin and maintained a patent IPI at the last follow-up (124+/-95 days). One patient required multiple tPA injections for recurrent fibrin formation. In another patient, a small hyphema developed after the tPA injection, which did not occlude the IPI. When compared with the natural course in a very similar group of patients previously reported, tPA had a statistically significant beneficial effect in the maintenance of IPI patency (P = 0.040). CONCLUSIONS: Intraocular tPA can be safely used to lyse postoperative fibrin occluding the IPI in eyes with silicone oil tamponade. Early lysis of this fibrin maintains IPI patency.

Adult↗
PubMed1987

Prolapse of a rigid anterior chamber lens through an iridectomy: report of ten cases.

I have observed ten cases in which a rigid anterior chamber lens prolapsed through the iridectomy. The lens dislocation was associated with cystoid macular edema in four cases and threatened the cornea in two cases. Vitrectomy and replacement with a flexible lens resulted in good vision. Removing the prolapsed lens haptic proved to be easy. Visual prognosis is good.

Aged↗
PubMed1990

[Biometry of the anterior chamber of the eye in Nd:YAG laser iridectomy].

In a prospective clinical study covering 41 eyes (28 patients) with narrow-angle glaucoma the central and peripheral anterior chamber depths were determined biomicroscopically before and after Nd:YAG laser iridectomy. In 29 eyes the central anterior chamber depth was also measured by ultrasonography. In contrast to the increase in central anterior chamber depth, which was only slight, the increase in the peripheral anterior chamber depth was statistically significant (P less than 0.01).

Anterior Chamber↗
PubMed1982

[Laser Iridectomy (author's transl)].

During the period mentioned 150 laser iridectomies were performed using the pulsed argon laser (BRITT Corp). With the help of a specially developed three mirror glass, (Stiegler) it is possible, without exception, to penetrate the iris in one session, regardless of its color or the depth of the anterior chamber. The technique used, and the tonographic and histologic investigations and results are discussed. The findings provide a new insight into the mechanism of out flow in glaucoma.

Humans↗
PubMed1982

[Argon laser iridectomy and gonioplasty in the treatment of angle-closure glaucoma].

Treatment of the narrow angle in angle-closure glaucoma depends on iridectomy and mechanical opening of the angle if an argon laser is used for photocoagulation. The effect of the heat is to shrink the iris tissue (gonioplasty) and to free the angle. Maximum power and safety of the laser beam are achieved by utilizing convex contact lenses on the cornea.

Glaucoma↗
PubMed1980

[Differential diagnosis of postoperative glaucoma following iridectomy and filtering procedures (author's transl)].

The various causes of elevated intraocular pressure following glaucoma surgery are described. One has to differentiate between failures after peripheral iridectomy (Table 1) and those following filtering interventions. The clinical picture of a postoperative narrow-angle glaucoma must be analyzed carefully; it may be due to pupillary block, plateau-iris syndrome or even to a ciliary block (malignant glaucoma). The failure of filtering procedures may be due to mechanisms blocking the trephination opening, cicatrization of the conjunctiva or a ciliary block. The diagnosis criteria of the different conditions and the respective therapeutic measures are outlined.

Diagnosis, Differential↗